Abstract: Method and apparatuses for diffuse optical tomography (DOT) are disclosed herein. A DOT device includes a substrate, one or more radiation sources, a plurality of detectors, and structures disposed over the second surface of the plurality of detectors. The one or more radiation sources are disposed over or under a surface of the substrate. Each detector of the plurality of detectors has a first surface and a second surface. The first surface is opposite the second surface. The first surface of the plurality of detectors disposed over or under the surface of the substrate. The method of DOT method of includes emitting and scattering radiation from one or more sources of a DOT device; detecting scattered radiation with a plurality of detectors of the DOT device; and translating the scattered radiation that is detected into data.

Abstract: Aspects of the present disclosure relate to connection blocks and pump manifold systems, and related methods, for pumping operations (such as frac operations). In one implementation, a connection block for disposition along a pump manifold of a pump system includes a first end hub having a first tube and a first outer shoulder extending outwardly relative to the first tube. The connection block includes a second end hub opposing the first end hub. The second end hub has a second tube and a second outer shoulder extending outwardly relative to the second tube. The connection block includes one or more faces between the first end hub and the second end hub.

Abstract: Aspects of the present disclosure relate to crane systems and pump manifold systems, and related methods, for pumping operations (such as frac operations). In one or more embodiments, a pump manifold system includes a plurality of connection blocks, a plurality of conduits coupled between the plurality of connection blocks, and a crane system. The crane system includes a base, and a first crane coupled to the base and configured to extend relative to a first side of the at least one conduit. The first crane is pivotable relative to the at least one conduit.

Abstract: A method for synthesising speech from text includes receiving text and encoding, by way of an encoder module, the received text. The method further includes determining, by way of an attention module, a context vector from the encoding of the received text, wherein determining the context vector comprises at least one of: applying a threshold function to an attention vector and accumulating the thresholded attention vector, or applying an activation function to the attention vector and accumulating the activated attention vector. The method further includes determining speech data from the context vector.

Abstract: A toy figure assembly can be interconnected to construct a toy figure. The mating parts of the toy figure assembly are structured for friction fit attachment and include an upper body part including a neck portion and a trunk portion; a lower body part including a rod portion, a stud portion, a legs portion, and a feet portion; and arm parts having a hand portion, a forearm portion, an elbow portion, an upper arm portion, and a shoulder portion.

Abstract: A computer system monitors a financial transaction system that contains a plurality of remote transaction machines, e.g., automated teller machines (ATMs). The computer system detects and analyzes whether any of the automated teller machines has an outage, whereby customers may be experiencing failed financial transactions. When an outage occurs, a severity level is selected by processing outage data. For example, the computer system determines a measure of the number of failed transactions and then selects a severity level of the outage from which the appropriate recovery procedure can then be initiated. When the transaction system comprises a plurality of networks, the severity level of an outage may be determined by aggregating or separately processing outage data for the networks. Outage ATMs may be prioritized from the number of corresponding failed transactions, so that the prioritization can be included in an indicator that initiates resolution of the outage.

Abstract: A toy figure assembly can be interconnected to construct a toy figure. The mating parts of the toy figure assembly are structured for friction fit attachment and include an upper body part including a neck portion and a trunk portion; a lower body part including a rod portion, a stud portion, a legs portion, and a feet portion; and arm parts having a hand portion, a forearm portion, an elbow portion, an upper arm portion, and a shoulder portion.

Abstract: A computer system monitors a financial transaction system that contains a plurality of remote transaction machines, e.g., automated teller machines (ATMs). The computer system detects and analyzes whether any of the automated teller machines has an outage, whereby customers may be experiencing failed financial transactions. When an outage occurs, a severity level is selected by processing outage data. For example, the computer system determines a measure of the number of failed transactions and then selects a severity level of the outage from which the appropriate recovery procedure can then be initiated. When the transaction system comprises a plurality of networks, the severity level of an outage may be determined by aggregating or separately processing outage data for the networks. Outage ATMs may be prioritized from the number of corresponding failed transactions, so that the prioritization can be included in an indicator that initiates resolution of the outage.

Abstract: The present invention makes available methods and reagents for modulating proliferation or differentiation in a cell or tissue comprising contacting the cell with a hedgehog agonist, such as the compounds depicted in FIGS. 32 and 33. In certain embodiments, the methods and reagents may be employed to correct or inhibit an aberrant or unwanted growth state, e.g., by antagonizing a normal ptc pathway or agonizing smoothened or hedgehog activity.

Abstract: The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting the cell with a hedgehog antagonist of formula (I) in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize smoothened or hedgehog activity.

Abstract: A computer system monitors a financial transaction system that contains a plurality of remote transaction machines, e.g., automated teller machines (ATMs). The computer system detects and analyzes whether any of the automated teller machines has an outage, whereby customers may be experiencing failed financial transactions. When an outage occurs, a severity level is selected by processing outage data. For example, the computer system determines a measure of the number of failed transactions and then selects a severity level of the outage from which the appropriate recovery procedure can then be initiated. When the transaction system comprises a plurality of networks, the severity level of an outage may be determined by aggregating or separately processing outage data for the networks. Outage ATMs may be prioritized from the number of corresponding failed transactions, so that the prioritization can be included in an indicator that initiates resolution of the outage.

Abstract: Described is a method for operating an internal combustion engine (1), in which method at least one parameter of the exhaust gas flowing in an exhaust-gas duct (10) is detected by at least one exhaust-gas probe (30; 32), wherein the internal combustion engine (1) is at least temporarily turned over by a starting device (3), during which an injection and combustion of fuel does not take place, and during and/or after which the exhaust-gas probe (30; 32) is adjusted.

Abstract: The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting the cell with a hedgehog antagonist of formula (I) in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize smoothened or hedgehog activity.

Abstract: The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting the cell with a hedgehog antagonist of formula (I) in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize smoothened or hedgehog activity.

Abstract: The present invention makes available methods and reagents for modulating proliferation or differentiation in a cell or tissue comprising contacting the cell with a hedgehog agonist, such as the compounds depicted in FIGS. 32 and 33. In certain embodiments, the methods and reagents may be employed to correct or inhibit an aberrant or unwanted growth state, e.g., by antagonizing a normal ptc pathway or agonizing smoothened or hedgehog activity.

Abstract: Described is a method for operating an internal combustion engine (1), in which method at least one parameter of the exhaust gas flowing in an exhaust-gas duct (10) is detected by at least one exhaust-gas probe (30; 32), wherein the internal combustion engine (1) is at least temporarily turned over by a starting device (3), during which an injection and combustion of fuel does not take place, and during and/or after which the exhaust-gas probe (30; 32) is adjusted.

Abstract: The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting the cell with a hedgehog antagonist of formula (I) in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize smoothened or hedgehog activity.

Abstract: The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize smoothened or hedgehog activity.

Abstract: The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize smoothened or hedgehog activity.