Abstract: A biodegradable nanocomposite and a method of forming a biodegradable nanocomposite are provided. In one aspect, the biodegradable nanocomposite includes a biodegradable polymer and a reinforcing agent substantially dispersed throughout the biodegradable polymer by rapid depressurization of a supercritical fluid. The biodegradable nanocomposite further includes a plurality of pores formed in the nanocomposite, the plurality of pores having an average pore size greater than about 100 ?m.

Abstract: A biodegradable film and a method of forming a biodegradable film are provided. In one aspect, the biodegradable film includes a reinforced biodegradable polymer including a biodegradable polymer and a reinforcing agent substantially dispersed throughout the biodegradable polymer by rapid depressurization of a supercritical fluid wherein the reinforced biodegradable polymer is formed into the film.

Abstract: A biodegradable nanocomposite and a method of forming a biodegradable nanocomposite are provided. In one aspect, the biodegradable nanocomposite includes a biodegradable polymer and a reinforcing agent substantially dispersed throughout the biodegradable polymer by rapid depressurization of a supercritical fluid. The biodegradable nanocomposite further includes a plurality of pores formed in the nanocomposite, the plurality of pores having an average pore size greater than about 100 ?m.

Abstract: The present invention is directed to a system for anterior fixation of the spine that utilizes an elongated fixation plate. The plating system stabilizes the spine and promotes fusion and incorporation of a graft or implant in a portion of the spinal column. In one aspect of the invention, the fixation plate has a first end with a pair of holes. Bone screws extend through the holes to rigidly secure the plate to a first vertebra. The second end of the plate is provided with a pair of slots through which bone screws extend for engagement with a second vertebra. The screws extending through the slots are translatable in the slot to maintain compression of the spinal column portion. The plating system includes a retainer assembly that prevents screw back out. Methods and instruments relating to the plating system are also described.