Abstract: A nasal insufflator for powdered medicaments comprises a tubular body having a longitudinal air passageway. One end of the body has an end suitable for insertion into a nostril, the other end is provided with a squeeze bulb by which a stream of air is driven through the passageway and into the nostril of a user. Wholly within the body and intermediate its ends is a chamber into which can be placed a capsule of powdered medicament. The device is characterised by having a piercing means, eg a needle, which is reciprocable along the axis of the passageway by having its non-operative end mounted upon the inner wall of the bulb. Longitudinal depression of the bulb drives the piercing end of the piercing means through the end walls of a capsule mounted in the chamber. Release of the bulb draws the piercing end back to its non-operative position, thus leaving the capsule pierced and ready to be emptied by transverse depression of the bulb.