Abstract: Disclosed are a bionic tissue stent, a preparation method therefor and an application thereof. The preparation method of the present invention is a 3D printing demolding method, and the preparation method can achieve the high-precision 3D engineering fabrication of a hydrogel material. The bionic tissue stent obtained by using said preparation method has a microscopic fine mesh structure, pores communicate, porosity is high, and the specific surface area is large, especially for bionic cartilage stents and osteochondral stents; moreover, the present invention has great application value in the treatment of articular cartilage diseases.