Patents by Inventor Harry L. Walton, Jr.

Harry L. Walton, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilization of active plasminogen activator inhibitor-1
    Patent number: 5290764
    Abstract: Processes for stabilizing active PAI-1 protein comprising combining active PAI-1 protein with an aqueous buffer having an ionic strength of at least about 5 millisiemens and a sugar selected from the group consisting of monosaccharides and disaccharides, and/or subjecting the active PAI-1 protein to lyophilization, are disclosed. Also described are compositions, including pharmaceutical compositions and kits, which include the stabilized active PAI-1 protein, and therapeutic processes employing the same in the treatment of fibrinolysis.
    Type: Grant
    Filed: January 14, 1992
    Date of Patent: March 1, 1994
    Assignee: The Dupont Merck Pharmaceutical Company
    Inventors: Jodie L. Duke, Jr., Harry L. Walton, Jr., Thomas M. Reilly