Patents by Inventor Harry Leighton

Harry Leighton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cardiotonic compounds with inhibitory activity against beta-adrenergic receptors and phosphodiesterase
    Publication number: 20070117978
    Abstract: The present invention provides compounds possessing inhibitory activity against (3-adrenergic receptors and phosphodiesterase (PDE), including type 3 phosphodiesterase (PDE-3). The present invention further provides pharmaceutical compositions comprising such compounds, methods of preparing such compounds, and methods of using such compounds for regulating calcium homeostasis, for treating a disease, disorder or condition in which disregulation of calcium homeostasis is implicated and for treating cardiovascular disease, stroke, epilepsy, an ophthalmic disorder or migraine.
    Type: Application
    Filed: December 23, 2003
    Publication date: May 24, 2007
    Applicant: ARTESIAN THERAPECUTICS, INC
    Inventors: Gregory Hamilton, Harry Leighton
  • Compounds having simultaneous ability to block L-type calcium channels and to inhibit phosphodiesterase type 3 activity
    Publication number: 20070066619
    Abstract: The present invention provides compounds that possess inhibitory activity against PDE-3 and L-type calcium channels. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating cardiovascular disease, stroke, epilepsy, ophthalmic disorder or migraine.
    Type: Application
    Filed: August 4, 2006
    Publication date: March 22, 2007
    Applicant: Artesian Therapeutics, Inc.
    Inventors: Gregory Hamilton, Harry Leighton, Jeff Bechard, Beth Allison, John Gibson
  • Treatment of sleep disorders using sleep target modulators
    Publication number: 20060009465
    Abstract: The invention is directed to compositions used for treating sleep disorders. In addition, the invention provides convenient methods of treatment of a sleep disorder. Furthermore, the invention provides methods of treating sleep disorders using compositions that remain active for a discrete period of time to reduce side effects. More specifically, the invention is directed to the compositions and use of ester derivatized trazodone compounds for the treatment of sleep disorders.
    Type: Application
    Filed: January 21, 2003
    Publication date: January 12, 2006
    Inventors: Dale Edgar, David Hangauer, Harry Leighton
  • Treatment of CNS disorders using CNS target modulators
    Publication number: 20050080265
    Abstract: The invention is directed to compositions and methods useful for treating Central Nervous System (CNS) disorders. Furthermore, the invention provides compositions and methods of treating sleep disorders. More specifically, the invention is directed to the compositions and use of derivatized, histamine antagonists for the treatment of sleep disorders.
    Type: Application
    Filed: April 23, 2004
    Publication date: April 14, 2005
    Inventors: Dale Edgar, David Hangauer, Harry Leighton, Emmanuel Mignot, James White, Michael Solomon, Kazumi Shiosaki
  • Treatment of cns disorders using cns target modulators
    Publication number: 20050009730
    Abstract: The invention is directed to compositions used for treating Central Nervous System (CNS) disorders. In addition, the invention provides convenient methods of treatment of a CNS disorder. Furthermore, the invention provides methods of treating sleep disorders using compositions that remain active for a discrete period of time to reduce side effects. More specifically, the invention is directed to the compositions and use of derivatized, e.g., ester or carboxylic acid derivatized, antihistamine antagonists for the treatment of sleep disorders.
    Type: Application
    Filed: October 16, 2002
    Publication date: January 13, 2005
    Inventors: Dale Edgar, David Hangauer, Harry Leighton, Emmanuel Mignot