Patents by Inventor Harry O. Spiwek

Harry O. Spiwek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymorph of a pharmaceutical
    Patent number: 9255092
    Abstract: A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed.
    Type: Grant
    Filed: October 14, 2013
    Date of Patent: February 9, 2016
    Assignee: AbbVie Inc.
    Inventors: John F. Bauer, Azita Saleki-Gerhardt, Bikshandarkoil A. Narayanan, Sanjay R. Chemburkar, Ketan M. Patel, Harry O. Spiwek, Philip E. Bauer, Kimberly A. Allen
  • POLYMORPH OF A PHARMACEUTICAL
    Publication number: 20150031731
    Abstract: A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed.
    Type: Application
    Filed: October 14, 2013
    Publication date: January 29, 2015
    Applicant: AbbVie Inc.
    Inventors: John F. Bauer, Azita Saleki-Gerhardt, Bikshandarkoil A. Narayanan, Sanjay R. Chemburkar, Ketan M. Patel, Harry O. Spiwek, Philip E. Bauer, Kimberly A. Allen
  • Polymorph of a pharmaceutical
    Patent number: 8674112
    Abstract: A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: March 18, 2014
    Assignee: AbbVie Inc.
    Inventors: John F. Bauer, Azita Saleki-Gerhardt, Bikshandarkoil A. Narayanan, Sanjay R. Chemburkar, Ketan M. Patel, Harry O. Spiwek, Philip E. Bauer, Kimberly A. Allen
  • Polymorph of a Pharmaceutical
    Publication number: 20120232284
    Abstract: A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed.
    Type: Application
    Filed: May 25, 2012
    Publication date: September 13, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: John F. Bauer, Azita Saleki-Gerhardt, Bikshandarkoil A. Narayanan, Sanjay R. Chemburkar, Ketan M. Patel, Harry O. Spiwek, Philip E. Bauer, Kimberly A. Allen
  • Polymorph of a pharmaceutical
    Patent number: 8193367
    Abstract: A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: June 5, 2012
    Assignee: Abbott Laboratories
    Inventors: John F. Bauer, Azita Saleki-Gerhardt, Bikshandarkoil A. Narayanan, Sanjay R. Chemburkar, Ketan M. Patel, Harry O. Spiwek, Philip E. Bauer, Kimberly A. Allen
  • Polymorph of a Pharmaceutical
    Publication number: 20100144804
    Abstract: A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed.
    Type: Application
    Filed: December 22, 2009
    Publication date: June 10, 2010
    Applicant: Abbott Laboratories
    Inventors: John F. Bauer, Azita Saleki-Gerhardt, Bikshandarkoil A. Narayanan, Sanjay R. Chemburkar, Ketan M. Patel, Harry O. Spiwek, Philip E. Bauer, Kimberly A. Allen
  • Polymorph of a pharmaceutical
    Patent number: 7659405
    Abstract: A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed.
    Type: Grant
    Filed: September 21, 2006
    Date of Patent: February 9, 2010
    Assignee: Abbott Laboratories
    Inventors: John F. Bauer, Azita Saleki-Gerhardt, Bikshandarkoil A. Narayanan, Sanjay R. Chemburkar, Ketan M. Patel, Harry O. Spiwek, Philip E. Bauer, Kimberly A. Allen
  • Polymorph of a pharmaceutical
    Patent number: 7183416
    Abstract: A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed.
    Type: Grant
    Filed: July 29, 2004
    Date of Patent: February 27, 2007
    Assignee: Abbott Laboratories
    Inventors: Sanjay R. Chemburkar, Ketan Patel, Harry O. Spiwek
  • Processes and intermediates for preparing retroviral protease inhibitors
    Patent number: 6372905
    Abstract: The instant invention provides processes and intermediates employed in the synthesis of ((2S,3S,5S)-2-(2,6-dimethylphenoxyacetyl)-amino-3-hydroxy-5-(2S-(1-tetrahydropyrimid-2-onyl)-3-methyl-butanoyl)amino-1,6-diphenylhexane and analogs thereof.
    Type: Grant
    Filed: August 29, 2001
    Date of Patent: April 16, 2002
    Assignee: Abbott Laboratories
    Inventors: Sanjay R. Chemburkar, Ketan M. Patel, Harry O. Spiwek
  • Processes and intermediates for preparing retroviral protease inhibitors
    Publication number: 20020035254
    Abstract: The instant invention provides processes and intermediates employed in the synthesis of ((2S,3S,5S)-2-(2,6-dimethylphenoxyacetyl)-amino-3-hydroxy-5-(2S-(1-tetrahydropyrimid-2-onyl)-3-methyl-butanoyl)amino-1,6-diphenylhexane and analogs thereof.
    Type: Application
    Filed: August 29, 2001
    Publication date: March 21, 2002
    Inventors: Sanjay R. Chemburkar, Ketan M. Patel, Harry O. Spiwek
  • Process for the preparation of N-4-[(substituted phenyl)alkylheterocyclic]- N
    Patent number: 5580989
    Abstract: A process for preparing a compound of the structure I ##STR1## where A is oxygen and sulfur and R.sup.1 is selected from the group consisting of hydrogen, halogen, alkyl of one to six carbon atoms, alkoxy of one to six carbon atoms, and trifluoromethyl, and R.sup.2 is alkyl of one to four carbon atoms, comprising coupling a compound of formula II: ##STR2## where X is bromine or iodine, with an N-hydroxyurea compound of formula III: ##STR3## in the presence of a palladium catalyst followed by reaction of the product thus formed with an alkali metal isocyante.The compounds of formula I are inhibitors of the enzyme 5-lipoxygenase and are thus useful as therapeutic agents for the treatment of allergic and inflammatory disease conditions.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 3, 1996
    Assignee: Abbott Laboratories
    Inventors: James D. Ratajczyk, Juliette K. Busse, Sanjay R. Chemburkar, Daniel A. Dickman, Yi-Yin Ku, Hemantkumar H. Patel, Ramesh R. Patel, David P. Sawick, John N. Starr, Bhadra Shelat, Harry O. Spiwek