Patents by Inventor Harry P. Schane, Jr.

Harry P. Schane, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4.alpha.,5.alpha.-Epoxy-3,20-dioxopregnan e-2.alpha.,16.alpha.-dicarbonitrile and intermediates and process for preparation, method of use and compositions thereof
    Patent number: 4331663
    Abstract: 4.alpha.,5.alpha.-Epoxy-3,20-dioxopregnane-2.alpha.,16.alpha.-dicarbonitril e is prepared by decyclizing 4.alpha.,5.alpha.-epoxy-20-oxopregn-2-eno-[2,3-d]isoxazole-16.alpha.-carbo nitrile with strong base and is useful as an inhibitor of mineralocorticoid production and/or action without concomitant glucocorticoid inhibition in primates.
    Type: Grant
    Filed: June 19, 1981
    Date of Patent: May 25, 1982
    Assignee: Sterling Drug Inc.
    Inventors: Robert G. Christiansen, Malcolm R. Bell, Harry P. Schane, Jr.
  • Pituitary-adrenal inhibiting method
    Patent number: 4213977
    Abstract: The method of suppressing pituitary-adrenal function without producing peripheral glucocorticoid effects in a primate comprising administering to the primate an amount of (17.alpha.)-2'-(4-fluorophenyl)-2'H-pregna-2,4-dien-20-yno[3,2-c]-pyrazol- 17-ol effective in reducing the concentration of circulating hydrocortisone is disclosed.
    Type: Grant
    Filed: November 20, 1978
    Date of Patent: July 22, 1980
    Assignee: Sterling Drug Inc.
    Inventors: Harry P. Schane, Jr., Homer R. Harding, John E. Creange