Patents by Inventor Harry SOKOL

Harry SOKOL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10918678
    Abstract: The invention relates to a bacterial strain of species Faecalibacterium prausnitzii deposited at the CNCM under access number CNCM I-4573, for use in the treatment and/or prevention of an inflammatory gastrointestinal illness in an individual.
    Type: Grant
    Filed: January 23, 2017
    Date of Patent: February 16, 2021
    Assignees: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA), SORBONNE UNIVERSITE, ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
    Inventors: Philippe Langella, Rebeca Martin Rosique, Luis Bermudez Humaran, Florian Chain, Harry Sokol
  • Publication number: 20210000889
    Abstract: The present invention relates to methods for prognosing and treating metabolic diseases. The inventors demonstrated the association of obesity with the increase of intestinal IDO activity, which shifts tryptophan (Trp) metabolism from indole derivative but also IL-22 production towards kynurenine (Kyn) production. The inventors showed that the rewiring of Tip metabolism is possible towards a microbiota-dependent production of IL-22.
    Type: Application
    Filed: February 28, 2019
    Publication date: January 7, 2021
    Inventors: Fatima-Soraya TALEB, Harry SOKOL, Ludivine LAURANS
  • Publication number: 20200316138
    Abstract: The present invention relates to a bacterial strain of the Faecalibacterium prausnitzii species selected from a bacterial strain belonging to one of the phylogroups I, II and III, for use in the treatment and/or prevention of visceral abdominal pain in an individual. The present invention also concerns compositions comprising said bacterial strains as well as specific strains as such.
    Type: Application
    Filed: June 22, 2020
    Publication date: October 8, 2020
    Inventors: Philippe LANGELLA, Sylvie MIQUEL, Rebeca MARTIN ROSIQUE, Luis BERMUDEZ HUMARAN, Muriel THOMAS, Harry SOKOL, Frédéric CARVALHO, Vassilia THEODOROU
  • Patent number: 10736927
    Abstract: The present invention relates to methods and pharmaceutical compositions for preventing or treating inflammatory bowel diseases.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: August 11, 2020
    Assignees: INSERM (INSTITUTE NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MEDICALE), UNIVERSITÉ PIERRE ET MARIE CURIE (PARIS 6), INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP)
    Inventors: Harry Sokol, Mathias Lavie-Richard, Marie-Laure Michel, Bruno Michel Lamas, Philippe Langella
  • Publication number: 20200188450
    Abstract: The invention relates to a fecal microbiota sample for use in the prevention and/or treatment of infectious or non-infectious complications resulting from allogeneic hematopoietic stem cell (HSC) transplantation, or for the treatment of cancer in a recipient patient, said fecal microbiota sample and said hematopoietic stem cells originating from the same donor subject, or said fecal microbiota sample being administered prior to HSC transplantation.
    Type: Application
    Filed: January 26, 2018
    Publication date: June 18, 2020
    Inventors: Mohamad MOHTY, Harry SOKOL
  • Publication number: 20200155622
    Abstract: The present invention relates to the use of at least one Lactobacillus bacterium, or a composition comprising thereof or conditioned thereby, for decreasing a population of Bilophila wadsworthia or inhibiting the growth thereof
    Type: Application
    Filed: May 22, 2017
    Publication date: May 21, 2020
    Inventors: Harry SOKOL, Philippe LANGELLA, Jane NATIVIDAD, Patrick VEIGA, Johan VAN HYLCKAMA VLIEG
  • Publication number: 20190381115
    Abstract: The present invention relates to a bacterial strain of the Faecalibacterium prausnitzii species selected from a bacterial strain belonging to one of the phylogroups I, II and III, for use in the treatment and/or prevention of visceral abdominal pain in an individual. The present invention also concerns compositions comprising said bacterial strains as well as specific strains as such.
    Type: Application
    Filed: November 13, 2015
    Publication date: December 19, 2019
    Applicants: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (APHP), ECOLE D'INGENIEURS DE PURPAN
    Inventors: Philippe LANGELLA, Sylvie MIQUEL, Rebeca MARTIN ROSIQUE, Luis BERMUDEZ HUMARAN, Muriel THOMAS, Harry SOKOL, Frédéric CARVALHO, Vassilia THEODOROU
  • Publication number: 20190282638
    Abstract: The present invention relates to the preventive or curative treatment of metabolic syndrome and the associated disorders with AhR agonist or microorganism producing AhR agonist.
    Type: Application
    Filed: July 11, 2017
    Publication date: September 19, 2019
    Inventors: HARRY SOKOL, JANE MEA NATIVIDAD, BRUNO LAMAS, HENRI DUBOC, MATHIAS LAVIE-RICHARD, MARIE-LAURE MICHEL, PHILIPPE LANGELLA
  • Publication number: 20190030089
    Abstract: The invention relates to a bacterial strain of species Faecalibacterium prausnitzii deposited at the CNCM under access number CNCM I-4573, for use in the treatment and/or prevention of an inflammatory gastrointestinal illness in an individual.
    Type: Application
    Filed: January 23, 2017
    Publication date: January 31, 2019
    Applicants: Institut National De La Recherche Agronomique (INRA), Sorbonne Universite, Assistance Publique - Hopitaux de Paris
    Inventors: Philippe Langella, Rebeca Martin Rosique, Luis Bermudez Humaran, Florian Chain, Harry Sokol
  • Publication number: 20180250350
    Abstract: The present invention relates to methods and pharmaceutical compositions for preventing or treating inflammatory bowel diseases.
    Type: Application
    Filed: August 22, 2016
    Publication date: September 6, 2018
    Inventors: HARRY SOKOL, MATHIAS LAVIE-RICHARD, MARIE-LAURE MICHEL, BRUNO MICHEL LAMAS, PHILIPPE LANGELLA
  • Publication number: 20180092949
    Abstract: The present invention relates to a composition comprising a therapeutically effective amount of Bacteroides thetaiotaomicron or an extract thereof for use in the prevention or treatment of an infection in a subject who is immunodepressed, who is immunosuppressed, who has an immature immune system, and/or who has a weakness, and in which the composition comprises at most six species of bacteria and/or extracts thereof. The infections concerned are mainly intestinal infections, in particular those which affect non-human mammals and/or humans.
    Type: Application
    Filed: April 22, 2016
    Publication date: April 5, 2018
    Inventors: HARRY SOKOL, PHILIPPE LANGELLA, THOMAS WALTER HOFFMANN, CHANTAL BRIDONNEAU, HANG PHUONG PHAM, MATHIAS LAVIE-RICHARD
  • Publication number: 20180085429
    Abstract: A method for preventing or treating an inflammatory disease, such as inflammatory bowel disease and Crohn disease, is presented. The method includes administering to a patient a polypeptide having the amino acid sequence of SEQ ID NO: 1, a conservative derivative or a fragment thereof, a nucleic acid sequence encoding said polypeptide, a vector comprising said nucleic acid sequence or a host cell that has been transfected, infected or transformed by said nucleic acid sequence and/or by said vector.
    Type: Application
    Filed: November 3, 2017
    Publication date: March 29, 2018
    Inventors: Philippe LANGELLA, Benedicte PIGNEUR-ARNAUD, Jean-Marc CHATEL, Elodie QUEVRAIN, Philippe SEKSIK, Germain TRUGNAN, Florian CHAIN, Luis G BERMUDEZ-HUMARAN, Marie-Anne MAUBERT, Christophe MICHON, Harry SOKOL
  • Publication number: 20150335705
    Abstract: A polypeptide including or consisting of the amino acid sequence SEQ ID NO: 1, for use in the treatment or prevention of an inflammatory disease. A nucleic acid sequence encoding the polypeptide, a vector including the nucleic acid and a host cell including the nucleic acid sequence and/or a vector, for use in the treatment or prevention of an inflammatory disease are also described. A pharmaceutical composition including the polypeptide, the nucleic acid sequence, the vector or the host cell and a pharmaceutically acceptable carrier, for the treatment of inflammatory disease are also disclosed.
    Type: Application
    Filed: December 26, 2013
    Publication date: November 26, 2015
    Inventors: Philippe LANGELLA, Benedicte PIGNEUR-ARNAUD, Jean-Marc CHATEL, Elodie QUEVRAIN, Philippe SEKSIK, Germain TRUGNAN, Florian CHAIN, Luis G BERMUDEZ-HUMARAN, Marie-Anne MAUBERT, Christophe MICHON, Harry SOKOL