Patents by Inventor Harry W. Read

Harry W. Read has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bioassay for toxic substances activated by metabolic enzyme system
    Patent number: 5843696
    Abstract: A method for bioassaying for metabolic activation of toxicants from a xenobiotic compound by a metabolic enzyme system includes incubating the xenobiotic compound with a metabolic enzyme system known to produce toxicants during normal metabolic degradation processes and with a mitochondrial membrane preparation competent for enzymatic electron transfer. The production of a toxicant has a detrimental effect upon the electron transfer activity of the mitochondrial membrane preparation which can readily be assayed by observing changes in concentration of a selected redox indicator.
    Type: Grant
    Filed: November 1, 1995
    Date of Patent: December 1, 1998
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Harry W. Read, Karl Gustavson, George A. Blondin