Patents by Inventor Harsh Mahendra Trivedi

Harsh Mahendra Trivedi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220146512
    Abstract: Methods of determining one or more ratios of chemokines in gingival crevicular fluid of an individual selected from the group consisting of: MIF:MIP1a, M1F:CXCL1; MIF:CXCL5; MIF:CXCL8; M1F:CXCL2; and MIF:CXCL6 and methods of identifying an individual as having gingivitis comprising determining one or more ratios of the chemokines in gingival crevicular fluid are disclosed. Methods of treating individuals who are identified as having gingivitis by determining one or more ratios of the chemokines in gingival crevicular fluid are disclosed. Also disclosed are methods of monitoring the treatment individuals who have gingivitis.
    Type: Application
    Filed: December 17, 2019
    Publication date: May 12, 2022
    Applicant: Colgate-Palmolive Company
    Inventors: Camille ZENOBIA, Harsh Mahendra TRIVEDI, Ying YANG
  • Patent number: 11318003
    Abstract: A computer-implemented method including deriving a health profile of a user from a sample taken from the user and displaying a representation of the health profile on a display, wherein the representation of the health profile includes a list of undesirable oral health characteristics that are detectable from the sample. The representation of the health profile may also include a list of desirable oral health characteristics that are detectable from the sample. Furthermore, a user may select one of the undesirable health characteristics, and in response an indication of historical values associated within he selected one of the undesirable health characteristics may be displayed on the display.
    Type: Grant
    Filed: July 24, 2019
    Date of Patent: May 3, 2022
    Assignee: Colgate-Palmolive Company
    Inventors: Elizabeth Kelly Gittins, Harsh Mahendra Trivedi, John Gatzemeyer, Eduardo Jimenez, Sharon Kennedy
  • Publication number: 20220071868
    Abstract: Methods of increasing proteins that reduce signals associated with neutrophil recruitment and reducing proteins that induce neutrophil recruitment within an individuals gingival crevice are disclosed. The methods comprise applying to the individual's oral cavity in an amount effective to increase proteins that reduce signals associated with neutrophil recruitment and reduce proteins that induce neutrophil recruitment within an individuals gingival crevice, an oral care composition comprising: zinc oxide, zinc citrate, stannous fluoride, and optionally arginine and/or zingerone.
    Type: Application
    Filed: December 17, 2019
    Publication date: March 10, 2022
    Applicant: Colgate-Palmolive Company
    Inventors: Camille ZENOBIA, Carlo DAEP, Dandan CHEN, Harsh Mahendra TRIVEDI, James MASTERS
  • Publication number: 20220071867
    Abstract: Methods of increasing proteins that reduce signals associated with neutrophil recruitment and reducing proteins that induce neutrophil recruitment within an individuals gingival crevice are disclosed. The methods comprise applying to the individuals oral cavity in an amount effective to increase proteins that reduce signals associated with neutrophil recruitment and reduce proteins that induce neutrophil recruitment within an individuals gingival crevice, an oral care composition comprising: zinc phosphate, stannous fluoride and optionally, an organic acid buffer system.
    Type: Application
    Filed: December 17, 2019
    Publication date: March 10, 2022
    Applicant: Colgate-Palmolive Company
    Inventors: Camille ZENOBIA, Carlo DAEP, Dandan CHEN, Harsh Mahendra TRIVEDI, James MASTERS
  • Publication number: 20220071877
    Abstract: Methods of shifting biofilm composition in an individuals oral cavity are disclosed. The methods comprise applying to the individuals oral cavity an oral care composition in an amount effective to shift biofilm composition to increase the amount from healthy bacteria in biofilm relative to pathogenic bacteria in biofilm. The oral care composition comprising: zinc oxide, zinc citrate, and arginine. The shift in biofilm composition provides a balance having a greater amount of healthy bacteria in biofilm compared to pathogenic bacteria.
    Type: Application
    Filed: December 17, 2019
    Publication date: March 10, 2022
    Applicant: Colgate-Palmolive Company
    Inventors: Camille Zenobia, Carlo DAEP, Dandan CHEN, Harsh Mahendra TRIVEDI, James MASTERS
  • Publication number: 20210404006
    Abstract: Described herein are methods used for the detection of gingivitis and the monitoring of gingivitis in a subject.
    Type: Application
    Filed: September 10, 2021
    Publication date: December 30, 2021
    Applicants: Colgate-Palmolive Company, The Regents of the University of California
    Inventors: David T.W. WONG, Karolina Elzbieta KACZOR-URBANOWICZ, Harsh Mahendra TRIVEDI, James MASTERS
  • Publication number: 20210404005
    Abstract: Described herein are methods used for the detection of gingivitis and the monitoring of gingivitis in a subject.
    Type: Application
    Filed: September 10, 2021
    Publication date: December 30, 2021
    Applicants: Colgate-Palmolive Company, The Regents of the University of California
    Inventors: David T.W. WONG, Karolina Elzbieta KACZOR-URBANOWICZ, Harsh Mahendra TRIVEDI, James MASTERS
  • Publication number: 20210318306
    Abstract: Methods for identifying a composition that neutralizes toxicity of a lipopolysaccharide are disclosed. The methods comprise comparing the amount of cytokine and/or prostaglandin E2 secreted by cells that have Toll-like receptors activated by a lipopolysaccharide in the presence or absence of a test composition. Methods of neutralizing toxicity of a lipopolysaccharide in an individual's oral cavity using compositions identified neutralizing toxicity of a lipopolysaccharide are also disclosed. Method of neutralizing toxicity of a lipopolysaccharide in an individual's oral cavity using oral care compositions that comprise combinations of zinc oxide and zinc citrate are also disclosed.
    Type: Application
    Filed: April 2, 2021
    Publication date: October 14, 2021
    Applicant: Colgate-Palmolive Company
    Inventors: Dandan Chen, Harsh Mahendra Trivedi, James Masters
  • Publication number: 20210308028
    Abstract: Method of improving tissue integrity of tissue that functions as a barrier are provided. Method of protecting and maintaining tissue integrity of tissue that functions as a barrier are provided. Method of repairing damage to tissue that functions as a barrier, and to restoring and improving function of such damaged tissue are provided. Methods of improving, maintaining, protecting, repairing and/or restoring the integrity of tissue which functions as a barrier and repair of damage to and healing of wounds to such tissue improves, maintains, protects, repairs and restores immunity. The methods comprising contacting the tissue with an effective amount of a composition comprising one or more sources of zinc ions such as zinc oxide, zinc citrate, or combination thereof zinc oxide and zinc citrate, and optionally further comprising arginine and/or one or more neutral amino acids.
    Type: Application
    Filed: March 30, 2021
    Publication date: October 7, 2021
    Applicant: Colgate-Palmolive Company
    Inventors: Ying Yang, James Masters, Harsh Mahendra Trivedi, Tulika Sarma
  • Publication number: 20210299018
    Abstract: This invention relates to oral care compositions comprising guanidine, zinc citrate and zinc oxide, and a fluoride source, as well as to methods of using and of making these compositions.
    Type: Application
    Filed: March 26, 2021
    Publication date: September 30, 2021
    Inventors: Carlo DAEP, Harsh Mahendra TRIVEDI, Paul THOMSON
  • Patent number: 11124833
    Abstract: Described herein are methods used for the detection of gingivitis and the monitoring of gingivitis in a subject.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: September 21, 2021
    Assignee: Colgate-Palmolive Company
    Inventors: David T. W. Wong, Karolina Elzbieta Kaczor-Urbanowicz, Harsh Mahendra Trivedi, James Masters
  • Patent number: 11116708
    Abstract: Personal care compositions including a naringin:zinc complex and methods for preparing and using the same are provided. The personal care compositions may include a carrier and a naringin:zinc complex having a 2:1 naringin to zinc molar ratio.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: September 14, 2021
    Assignee: Colgate-Palmolive Company
    Inventors: Shujiang Cheng, Zeenat Nabi, Laurence Du-Thumm, Qiang Wu, Jane Ong, Halyna Siomyk, Harsh Mahendra Trivedi, James Masters, Chi-Yuan Cheng, Donghui Wu
  • Publication number: 20210196598
    Abstract: Methods of selectively inhibiting co-aggregation of commensal and pathogenic bacteria in a population of bacteria that comprises commensal and pathogenic bacteria, such as in an individual's oral cavity are disclosed. Methods of reducing biofilm in an individual's oral cavity are disclosed. Methods of inhibiting biofilm formation in a population of bacteria that comprises commensal and pathogenic bacteria are disclosed. Methods of identifying a compound or composition that enhances the selective inhibition of coaggregation of commensal and pathogenic bacteria by arginine or an arginine oligomer are also disclosed. Methods of identifying a compound or composition that enhances the selective inhibition of biofilm formation of commensal and pathogenic bacteria by arginine or an arginine oligomer are disclosed.
    Type: Application
    Filed: December 19, 2019
    Publication date: July 1, 2021
    Applicant: Colgate-Palmolive Company
    Inventors: Carlo DAEP, Harsh Mahendra TRIVEDI
  • Publication number: 20210177724
    Abstract: Described herein are oral care compositions comprising—in relevant part—an effective amount of inulin. Methods of making and using these compositions are also described.
    Type: Application
    Filed: November 30, 2020
    Publication date: June 17, 2021
    Applicant: Colgate-Palmolive Company
    Inventors: Salima Hammadi, Harsh Mahendra TRIVEDI, Melissa MARTINETTI, David SURIANO, Michael FITZGERALD, Yun XU, Shashank POTNIS, Karthik SAMBANTHAMOORTHY
  • Patent number: 10980424
    Abstract: An oral care evaluation process may include: illuminating soft oral tissue within an oral cavity with a light source emitting a spectrum of light which induces fluorescence in an organic compound; generating image data for an image of the soft oral tissue while illuminating the soft oral tissue, the image comprising a plurality of pixels; and evaluating oral hygiene using a programmable processor programmed to assess an attribute of each pixel of the image.
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: April 20, 2021
    Assignee: Colgate-Palmolive Company
    Inventors: Michael Pacelli, Hrebesh Molly Subhash, Michael Fitzgerald, Harsh Mahendra Trivedi
  • Publication number: 20210000725
    Abstract: An oral care composition including rottlerin in an amount sufficient to reduce a growth of gram-positive bacteria in a mouth treated with the oral care composition.
    Type: Application
    Filed: November 27, 2017
    Publication date: January 7, 2021
    Applicant: Colgate-Palmolive Company
    Inventors: Karthik SAMBANTHAMOORTHY, Harsh Mahendra TRIVEDI
  • Patent number: 10773105
    Abstract: This invention relates to oral care compositions comprising zingerone, bisabolol, a stannous ion source, zinc oxide, and zinc citrate, as well as to methods of using and of making these compositions.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: September 15, 2020
    Assignee: Colgate-Palmolive Company
    Inventors: Ying Yang, Dandan Chen, Robert D'Ambrogio, Paul Thomson, Harsh Mahendra Trivedi, Michael Prencipe, James Masters, Stanislav Jaracz
  • Publication number: 20200269036
    Abstract: An oral care implement having conductive protrusions. In one embodiment, the oral care implement includes a handle and a head coupled to the handle. Furthermore, the oral care implement includes a power source. A plurality of conductive protrusions may be electrically coupled to the power source. The plurality of conductive protrusions may include a base proximate the head and a distal end spaced from the head. Furthermore, at least one of the conductive protrusions may taper from the base to the distal end.
    Type: Application
    Filed: May 1, 2020
    Publication date: August 27, 2020
    Applicant: Colgate-Palmolive Company
    Inventors: Patrik JOHANSSON, Harsh Mahendra TRIVEDI, Douglas HOHLBEIN
  • Patent number: 10736831
    Abstract: An oral care composition comprising a surfactant having formula [R(OC2H4)xOSO3]2M wherein R is a saturated or unsaturated alkyl group with an alkyl chain length of 8 to 30 carbon atoms; x is from 0 to 10; and M is a divalent metal cation selected from zinc cations, copper cations and stannous cations is provided.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: August 11, 2020
    Assignee: Colgate-Palmolive Company
    Inventors: Kevin Mark Kinscherf, Lyndsay Schaeffer-Korbylo, Gregory Szewczyk, Carl Myers, Harsh Mahendra Trivedi
  • Publication number: 20200246242
    Abstract: Personal care compositions including a naringin:zinc complex and methods for preparing and using the same are provided. The personal care compositions may include a carrier and a naringin:zinc complex having a 2:1 naringin to zinc molar ratio.
    Type: Application
    Filed: December 19, 2017
    Publication date: August 6, 2020
    Applicant: Colgate-Palmolive Company
    Inventors: Shujiang CHENG, Zeenat NABI, Laurence DU-THUMM, Qiang WU, Jane ONG, Halyna SIOMYK, Harsh Mahendra TRIVEDI, James MASTERS, Chi-Yuan CHENG, Donghui WU