Abstract: Various embodiments include techniques for processing transactions via a computer system interconnect with a distributed firewall. The distributed firewall includes separate firewalls for various initiators of transactions and separate firewalls for various targets of those transactions. As a result, transactions proceed, for example, along the shortest path from the initiator to the target, rather than being routed through a centralized firewall. In addition, firewall transactions, for example, may be remapped such that initiators address the initiator firewalls and target firewalls via a unified address space, without having to maintain separate base addresses for each initiator firewall and target firewall. As a result, application programs, for example, can execute transactions with increased performance on a computer system as compared to prior approaches.