Abstract: The present invention refers to conjugates of erythropoietin with poly(ethylene glycol) comprising an erythropoietin glycoprotein having an N-terminal ?-amino group and having the in vivo biological activity of causing bone marrow cells to increase production of reticulocytes and red blood cells and selected from the group consisting of human erythropoietin and analogs thereof which have the sequence of human erythropoietin modified by the addition of from 1 to 6 glycosylation sites or a rearrangement of at least one glycosylation site; said glycoprotein being covalently linked to one poly(ethylene glycol) group of the formula —CO—(CH2)x—(OCH2CH2)m—OR wherein the —CO of the poly(ethylene glycol) group forms an amide bond with said N-terminal ?-amino group; and wherein R is lower alkyl; x is 2 or 3; and m is from about 450 to about 1350.

Abstract: Apparatus for separating fluid mixtures includes plural tubular membranes parallel to each other. Each of the membranes has an inner lumen and the flow direction is from the exterior of the membrane to the inner lumen. Each tube is surrounded by a larger diameter feed tube and a gap is formed between the outside service of the tubular membrane and the inside service of the feed tube. This annulus provides a feed flow channel for the fluid mixture along the outer surface of the tubular membrane. The annulus has first and second ends connected to entrance and discharge ports respectively of the feed flow. The inner lumen of the tubular membranes are sealed from the annular gap and provided with a connection for the discharge of the permeate flow.

Abstract: A device is provided for separating images captured by data acquisition into multiple partial images in a separator stage and/or for recombining partial images in a combiner stage. Partial-data buffers (e.g., FIFOs) are provided for the partial images in the separator stage and/or in the combiner stage. The partial-image data buffered in the partial-data buffers also includes redundantly buffered information about at least one adjacent partial image so that, when recombining the partial images, the artifacts produced by filtering the corresponding partial images, which is needed for recombination, lie outside the partial-image data areas needed for recombining the partial images into an overall image.

Abstract: Apparatus for separating of fluid mixtures. A number of tubular membranes are arranged parallel to each other. Each of the membranes has an inner lumen and the flow direction is from the exterior of the membrane to the inner lumen. Each tube is surrounded by a larger diameter feed tube and a gap is formed between the outside service of the tubular membrane and the inside service of the feed tube. This annulus provides a feed flow channel for the fluid mixture along the outer surface of the tubular membrane. The annulus has a first and second end each being connecting with means for entrance and discharge respectively of the feed flow and with means to direct the feed flow through the channels. The inner lumen of the tubular membranes are sealed from the annular gap and provided with a connection for the discharge of the permeate flow.

Abstract: The present invention refers to conjugates of erythropoietin with poly(ethylene glycol) comprising an erythropoietin glycoprotein having an N-terminal &agr;-amino group and having the in vivo biological activity of causing bone marrow cells to increase production of reticulocytes and red blood cells and selected from the group consisting of human erythropoietin and analogs thereof which have the sequence of human erythropoietin modified by the addition of from 1 to 6 glycosylation sites or a rearrangement of at least one glycosylation site; said glycoprotein being covalently linked to one poly(ethylene glycol) group of the formula

Abstract: Disclosed is a mounting structure for mounting a horizontal insertion loading data storage drive in a data storage library having downwardly inclined shelves. A bracket mounts the data storage drive, and support bars are mounted in parallel in the data storage library and support the bracket on each side at a downwardly inclined angle. Thus, the horizontal insertion loading data storage drive is mounted at the downwardly inclined angle to receive data storage media from a robot accessor at the angle of the downwardly inclined shelves. The mounting structure support bars are parallel slides which slidably support the bracket at the downwardly inclined angle. A ratchet bar is mounted in the library at the downwardly inclined angle, and has a plurality of ratchet holes in the downwardly inclined direction. A latch is mounted on the bracket for engaging the ratchet holes of the ratchet bar to support the bracket and data storage drive against sliding on the support bar slides.

Abstract: The present invention provides an Input/Output station of an automated storage and retrieval system, or library, which uses an elevator mechanism to vertically translate a cartridge or a magazine containing a plurality of cartridges from a maximum vertical position above the top surface of the library to a minimum vertical position beneath the top surface and internal to the library. The Input/Output station is aligned with the other components of the library such that the vertical path of the elevator mechanism does not interfere with the path of the accessor. The operation of the Input/Output station does not pause the accessor and thus, does not interfere with the operation of the other automated processes within the library. Cartridges can be added to or removed from the library using the Input/Output station while the accessor is moving a different cartridge from a storage cell in the storage array to a drive.

Abstract: The present invention provides an Input/Output station of an automated storage and retrieval system, or library, which uses an elevator mechanism to vertically translate a cartridge or a magazine containing a plurality of cartridges from a maximum vertical position above the top surface of the library to a minimum vertical position beneath the top surface and internal to the library. The Input/Output station is aligned with the other components of the library such that the vertical path of the elevator mechanism does not interfere with the path of the accessor. The operation of the Input/Output station does not pause the accessor and thus, does not interfere with the operation of the other automated processes within the library. Cartridges can be added to or removed from the library using the Input/Output station while the accessor is moving a different cartridge from a storage cell in the storage array to a drive.