Patents by Inventor Hartmut Merdes

Hartmut Merdes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6287867
    Abstract: The invention concerns the use of an asymmetric porous membrane for the evenly distributed concentration of a substance which is not or not substantially adsorbed to the membrane and which is brought into contact with the membrane in the form of a membrane-wetting solution on the fine-pored side of the membrane.
    Type: Grant
    Filed: August 26, 1994
    Date of Patent: September 11, 2001
    Assignee: Roche Diagnostics GmbH
    Inventors: Herbert Harttig, Hartmut Merdes, Hans Lange, Manfred Zeiler
  • Patent number: 6214570
    Abstract: The subject matter of the application is a method for the separation of non-HDL lipoproteins from biological fluids in a carrier through which liquids can flow. The carrier contains a precipitating agent for non-high density lipoproteins (non-HDLs).
    Type: Grant
    Filed: July 14, 1998
    Date of Patent: April 10, 2001
    Assignee: Roche Diagnostics GmbH
    Inventors: Walter Rittersdorf, Ulfert Deneke, Gerhard Hiller, Hartmut Merdes, Klaus Buecker, Uwe Goebbert
  • Patent number: 6171849
    Abstract: An apparatus comprising a first porous carrier and a second porous carrier for evaluating biological fluid samples is disclosed. The apparatus is used for separating non high density lipoprotein (non-HDL) from a lipoprotein in a body sample and for determining high density lipoprotein (HDL) cholesterol in a HDL and non high density lipoprotein (non-HDL) in a body sample.
    Type: Grant
    Filed: January 12, 2000
    Date of Patent: January 9, 2001
    Assignee: Roche Diagnostics GmbH
    Inventors: Walter Rittersdorf, Ulfert Deneke, Gerhard Hiller, Hartmut Merdes, Klaus Buecker, Uwe Goebbert
  • Patent number: 6057120
    Abstract: The invention concerns the use of redox-active compounds for the production of detection reagents for a method for the determination of an analyte as well as reagent kits that contain these redox-active compounds. In addition new redox-active compounds are disclosed.
    Type: Grant
    Filed: September 22, 1997
    Date of Patent: May 2, 2000
    Assignee: Roche Diagnostics GmbH
    Inventors: Dieter Heindl, Rupert Herrmann, Joachim Hones, Hans-Peter Josel, Martina Junius-Comer, Hartmut Merdes, Axel Schmidt, Ernst Selbertinger
  • Patent number: 6036919
    Abstract: The present invention concerns a diagnostic test carrier for the determination of an analyte from whole blood with the aid of a reagent system contained in the carrier which includes a colour forming reagent with a test field which has a sample application side onto which the blood sample is applied and a detection side on which an optically detectable change takes place as a result of the reaction of analyte with the reagent system and which is constructed in such a way that erythrocytes present in the sample do not reach the detection side, which is characterized in that the test field comprises a transparent foil onto which a first and a second film layer are applied on top of one another and wherein the first layer located on the transparent foil scatters light considerably less in a wet state than the overlying second layer and wherein the side of the foil on which the first layer is applied which is opposite to the foil side is the detection side and the side of the second layer which is opposite to the
    Type: Grant
    Filed: July 21, 1997
    Date of Patent: March 14, 2000
    Assignee: Roche Diagnostic GmbH
    Inventors: Detlef Thym, Wofgang-Reinhold Knappe, Rudolf Pachl, Hartmut Merdes, Robert Lorenz
  • Patent number: 5786164
    Abstract: The invention relates to a method useful in separating non-high density lipoproteins, referred to as "non-HDLs", from biological fluids containing them. A porous carrier is provided which contains a non-HDL precipitating agent. One need only contact the sample of interest to the carrier for one minute or less, after which the precipitated non-HDL-s are no longer present in the sample being tested. The applications of the method include the ability to determine high density lipoproteins in the sample without interference from non-HDLs.
    Type: Grant
    Filed: June 11, 1996
    Date of Patent: July 28, 1998
    Assignee: Boehringer Mannheim GmbH
    Inventors: Walter Rittersdorf, Ulfert Deneke, Gerhard Hiller, Hartmut Merdes, Klaus Buecker, Uwe Goebbert
  • Patent number: 5580743
    Abstract: The invention relates to a method useful in separating non-high density lipoproteins, referred to as "non-HDLs", from biological fluids containing them. A porous carrier is provided which contains a non-HDL precipitating agent. One need only contact the sample of interest to the carrier for one minute or less, after which the precipitated non-HDLs are no longer present in the sample being tested. The applications of the method include the ability to determine high density lipoproteins in the sample without interference from non-HDLs.
    Type: Grant
    Filed: February 6, 1995
    Date of Patent: December 3, 1996
    Assignee: Boehringer Mannheim GmbH
    Inventors: Walter Rittersdorf, Ulfert Deneke, Gerhard Hiller, Hartmut Merdes, Klaus Buecker, Uwe Goebbert
  • Patent number: 5426030
    Abstract: The invention relates to an apparatus and a method useful in separating non-high density lipoproteins, referred to as "non-HDLs", from biological fluids containing them. A porous carrier is provided which contains a non-HDL precipitating agent. One need only contact the sample of interest to the carrier for one minute or less, after which the precipitated non-HDLs are no longer present in the sample being tested. The applications of the method include the ability to determine high density lipoproteins in the sample without interference from non-HDLs.
    Type: Grant
    Filed: August 24, 1990
    Date of Patent: June 20, 1995
    Assignee: Boehringer Mannheim GmbH
    Inventors: Walter Rittersdorf, Ulfert Deneke, Gerhard Hiller, Hartmut Merdes, Klaus Buecker, Uwe Goebbert
  • Patent number: 4985414
    Abstract: New 1-naphtholphthalein monophosphates of the formula ##STR1## wherein each of R.sup.1 and R.sup.2 is hydrogen or halogen, and each of M.sup.1 and M.sup.2 is a proton or an alkali metal, alkaline earth metal, ammonium, dicyclohexylammonium, tetraalkylammonium or alkanolammonium cation, and the tautomeric transformation products thereof, are useful as substrates for detection and photometric determination of alkaline phosphotase.
    Type: Grant
    Filed: November 18, 1988
    Date of Patent: January 15, 1991
    Assignee: Boehringer Mannheim GmbH
    Inventors: Werner Guethlein, Hartmut Merdes
  • Patent number: 4665023
    Abstract: The present invention provides imidazole derivatives of the general formula: ##STR1## wherein R, R.sub.1 and R.sub.2 are defined hereinbelow. The present invention is also concerned with processes for the preparation of these imidazole derivatives and with the use thereof as redox indicators.
    Type: Grant
    Filed: March 29, 1985
    Date of Patent: May 12, 1987
    Assignee: Boehringer Mannheim GmbH
    Inventors: Ulfert Deneke, Werner Guthlein, Manfred Kuhr, Hartmut Merdes, Hans-Rudiger Murawski, Hans Wielinger
  • Patent number: 3957766
    Abstract: Certain novel nitrofuran compounds of the formula: ##SPC1##WhereinHet is an aromatic heterocylic linkage;B is a bond or vinylene;Y is O or S;m is 0 or 1;X is hydrogen, lower alkyl or alkanoyl; andThe R's are variously defined;Are outstandingly effective bacteriostats and bactericides.
    Type: Grant
    Filed: September 20, 1972
    Date of Patent: May 18, 1976
    Assignee: Boehringer Mannheim G.m.b.H.
    Inventors: Herbert Berger, Rudi Gall, Hartmut Merdes, Kurt Stach, Winfriede Sauer, Wolfgang Vomel
  • Patent number: RE39915
    Abstract: An apparatus comprising a first porous carrier and a second porous carrier for evaluating biological fluid samples is disclosed. The apparatus is used for separating non high density lipoprotein (non-HDL) from a lipoprotein in a body sample and for determining high density lipoprotein (HDL) cholesterol in a HDL and non high density lipoprotein (non-HDL) in a body sample.
    Type: Grant
    Filed: August 20, 2003
    Date of Patent: November 6, 2007
    Assignee: Roche Diagnostics GmbH
    Inventors: Walter Rittersdorf, Ulfert Deneke, Gerhard Hiller, Hartmut Merdes, Klaus Buecker, Uwe Goebbert