Patents by Inventor Hartmut Voelskow

Hartmut Voelskow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5158888
    Abstract: Streptomyces parvullus, DSM 3816, produces on aerobic fermentation new antibiotics which are distinguished by antimicrobial activity even after derivatization.
    Type: Grant
    Filed: February 19, 1992
    Date of Patent: October 27, 1992
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Peter Hammann, Susanne Grabley, Hartmut Voelskow, Burkhard Sachse, Wolfgang Raether, Carlo Giani, Gerhard Seibert
  • Patent number: 5011827
    Abstract: The invention relates to elaiophyline derivatives of the formula I ##STR1## in which R.sup.1 and R.sup.1' are identical or different and represent a radical of the formula II/or III ##STR2## in which R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.7 have the meanings given. The invention furthermore relates to a process for the preparation of these elaiophyline derivatives and also the use of the lattere as medicaments, in particular as anthelmintically acting medicaments.
    Type: Grant
    Filed: October 28, 1988
    Date of Patent: April 30, 1991
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Gerhard Kretzschmar, Dieter Duwel, Susanne Grabley, Peter Hammann, Gerhard Seibert, Hartmut Voelskow, Carlo Giani
  • Patent number: 4914216
    Abstract: Streptomyces parvullus, DSM 3816, produces on aerobic fermentation new antibiotics which are distinguished by antimicrobial activity even after derivatization.
    Type: Grant
    Filed: December 22, 1987
    Date of Patent: April 3, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Peter Hammann, Susanne Grabley, Hartmut Voelskow, Burkhard Sachse, Wolfgang Raether, Carlo Giani, Gerhard Seibert
  • Patent number: 4861775
    Abstract: Streptomyces spec. DSM 3813 produces novel compounds with a basic phenoxazinone structure, which have an antifungal and antiviral action and can be used as lipoxygenase inhibitors.
    Type: Grant
    Filed: August 25, 1987
    Date of Patent: August 29, 1989
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Axel Zeeck, Sabine Breiding-Mack, Susanne Grabley, Hartmut Voelskow, Gerhard Seibert
  • Patent number: 4861796
    Abstract: 2-Acetylaminogentisic acid has been isolated from the culture broth after cultivation of a bacterium of the genus Streptomyces. This compound has antibacterial actions against Gram-positive and Gram-negative bacteria.
    Type: Grant
    Filed: December 19, 1988
    Date of Patent: August 29, 1989
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Axel Zeeck, Sabine Breiding-Mack, Susanne Grabley, Hartmut Voelskow, Gerhard Seibert
  • Patent number: 4849409
    Abstract: Streptazoline is reacted with naphthoquinones in a Diels-Alder reaction, and the adduct is then oxidized. The resulting compounds have cytotoxic activity, in particular against leukemia cells, and have an antimicrobial action and act against protozoa.
    Type: Grant
    Filed: May 12, 1987
    Date of Patent: July 18, 1989
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Ullrich Hoppe, Susanne Grabley, Hartmut Voelskow, Merten Schlingmann, Hans P. Kraemer, Matthias Wiesner, Joachim Thiem
  • Patent number: 4828998
    Abstract: The strain Streptomyces coelicolor DSM 3030 excretes into the fermentation medium high yields of a bacteriolytic enzyme product which is very active against Gram-positive and Gram-negative bacteria. Preferred fermentation media contain sugar beet molasses and/or calcium ions.
    Type: Grant
    Filed: November 6, 1985
    Date of Patent: May 9, 1989
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Gerhard Wohner, Hartmut Voelskow, Paul Prave, Erich Luck, Gert-Wolfhard von Rymon Lipinski
  • Patent number: 4746615
    Abstract: It is possible by use of a sterilizable fluidized bed fermenter to carry out low-moisture fermentations. Fluidizable granulated microorganisms are used for this fermentation under sterile conditions in the fluidized bed fermenter which is initially operated as a bubble column.
    Type: Grant
    Filed: July 28, 1987
    Date of Patent: May 24, 1988
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Rainer Buchholz, Hans-Matthias Deger, Hartmut Voelskow, Rolf Woernle
  • Patent number: 4745059
    Abstract: L-Phenylalanine can be prepared using microorganisms belonging to the series comprising E. coli, Paracoccus denitrificans, Torula, Rhodotorula or Streptomyces after adaptation to phenylpyruvic acid, by amination with suitable sources of nitrogen. It is advantageous to employ the microorganism in the form of fixed cells.
    Type: Grant
    Filed: June 27, 1985
    Date of Patent: May 17, 1988
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hartmut Voelskow, Reinhold Keller, Merten Schlingmann, Martin Platen, Johann Then, Gerhard Wohner
  • Patent number: 4591639
    Abstract: Microbial polysaccharides can be quantitatively precipitated from their aqueous solutions, in particular directly from the fermentation solutions, in an acidic medium in the form of an adduct with a tertiary amine which has a long-chain alkyl radical. It is advantageous to add the amine to the polysaccharide solution and then to carry out the precipitation, in particular by adding the dispersion obtained to an acidic coagulation bath. The adducts are suitable for use as thickeners and for preparing the free polysaccharides.
    Type: Grant
    Filed: August 12, 1983
    Date of Patent: May 27, 1986
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Edgar Fischer, Hartmut Voelskow
  • Patent number: 4567140
    Abstract: Polysaccharides are obtained by fermentation using a mixed culture of several microorganisms, of which at least one also produces a polysaccharide in pure culture, which polysaccharides are suitable as viscosity regulators. A mixed culture of the strains Pseudomonas maltophilia DSM 2130 and Agrobacterium tumefaciens DSM 2128 is particularly suitable.
    Type: Grant
    Filed: April 21, 1983
    Date of Patent: January 28, 1986
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hartmut Voelskow, Merten Schlingmann
  • Patent number: 4467034
    Abstract: D-lactic acid is obtained by fermentation of a nutritive medium containing glucose and/or lactose and other usual additives by means of Lactobacillus bulgaricus DSM 2129.
    Type: Grant
    Filed: August 9, 1982
    Date of Patent: August 21, 1984
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hartmut Voelskow, Dieter Sukatsch