Abstract: A number of analytes are divided into groups based on at least either the elution position determined by silica gel column chromatography under the same condition or the partition ratio in a hexane-acetonitrile partition method. To each group, a compound obtained by labeling one of the compounds in the group by deuterium and/or carbon is assigned as the surrogate. After those surrogates are added as internal standard substances to a standard sample for the creation of calibration curves, a GC/MS analysis for the sample is performed and a calibration curve is created for each analyte. In the measurement of an unknown sample, the same set of surrogates are added to the sample and the GC/MS analysis is performed. A quantitative determination processor determines the quantity of each analyte by comparing a peak area ratio calculated from the analysis result with a calibration curve read from the database.

Abstract: A number of analytes are divided into groups based on at least either the elution position determined by silica gel column chromatography under the same condition or the partition ratio in a hexane-acetonitrile partition method. To each group, a compound obtained by labeling one of the compounds in the group by deuterium and/or carbon is assigned as the surrogate. After those surrogates are added as internal standard substances to a standard sample for the creation of calibration curves, a GC/MS analysis for the sample is performed and a calibration curve is created for each analyte. In the measurement of an unknown sample, the same set of surrogates are added to the sample and the GC/MS analysis is performed. A quantitative determination processor determines the quantity of each analyte by comparing a peak area ratio calculated from the analysis result with a calibration curve read from the database.

Abstract: For the detection and structural analysis of cathinone-based compounds subject to comprehensive regulation, three MS/MS measurements are repeated for a target sample: an MRM measurement; a product-ion scan measurement; and a product-ion scan measurement. Based on the positional coincidence of a peak on chromatograms obtained by the three measurements, non-cathinone-based compounds are excluded. From the MRM transition and the product-ion spectrum pattern, the kinds of functional groups are estimated and the structure of the cathinone-based compound is estimated.

Abstract: A method for quantitating a substance to be measured including: storing a database with which a relative calibration curve is registered; measuring an internal standard substance having a known concentration; calculating the peak area or the height of an internal standard substance by preparing a chromatogram on the basis of a mass spectrum of the internal standard substance; gaining a mass spectrum of the substance to be measured by measuring the substance; calculating the peak area or the height of the substance by preparing a chromatogram on the basis of the mass spectrum of the substance to be measured; and of calculating the concentration of the substance on the basis of the relative calibration curve, the peak area or the height of the internal standard substance and the peak area or the height of the substance.

Abstract: A chromatographic mass spectrometer 100, 150 is provided with a measuring portion 21 for measuring n-alkane of a number of different carbon numbers, and characterized by further having: a mass number storing portion 31 for storing the mass number for each n-alkane; and a mass chromatogram preparing portion 22 for preparing a mass chromatogram for each mass number by focusing on the mass number on the basis of the mass spectrum.

Abstract: A chromatographic mass spectrometer 100, 150 is provided with a measuring portion 21 for measuring n-alkane of a number of different carbon numbers, and characterized by further having: a mass number storing portion 31 for storing the mass number for each n-alkane; and a mass chromatogram preparing portion 22 for preparing a mass chromatogram for each mass number by focusing on the mass number on the basis of the mass spectrum.

Abstract: A method for quantitating a substance to be measured according to which a substance to be measured is quantitated is characterized by including: a database storing step of storing a database with which a relative calibration curve is registered; an internal standard substance measuring step of measuring an internal standard substance having a known concentration so that a mass spectrum of the internal standard substance is gained; an absolute value calculating step of calculating the peak area or the height of an internal standard substance by preparing a chromatogram on the basis of the mass spectrum of the internal standard substance; a substance to be measured measuring step of gaining a mass spectrum of the substance to be measured by measuring the substance to be measured; a measured value calculating step of calculating the peak area or the height of the substance to be measured by preparing a chromatogram on the basis of the mass spectrum of the substance to be measured; and a concentration of a substa

Abstract: When a standard specimen including a given reference component is analyzed after a separation condition is changed, a data processing section (31) acquires an actual measurement value of a peak of a reference component that appears in a chromatogram obtained by the analysis, and estimates a deviation of the retention time of a peak of an intended component on the basis of the actual measurement value and information on the retention time of the reference component before the separation condition stored in an analysis condition information storing section (34) is changed, to correct a measurement time range of the respective ion sets of an SIM measurement parameter which is stored in an analysis condition information storing section (34). An SIM measurement is conducted according to the parameter that is corrected when analyzing the intended specimen, to thereby make it possible to conduct a desired measurement by an operator.

Abstract: When a standard specimen including a given reference component is analyzed after a separation condition is changed, a data processing section (31) acquires an actual measurement value of a peak of a reference component that appears in a chromatogram obtained by the analysis, and estimates a deviation of the retention time of a peak of an intended component on the basis of the actual measurement value and information on the retention time of the reference component before the separation condition stored in an analysis condition information storing section (34) is changed, to correct a measurement time range of the respective ion sets of an SIM measurement parameter which is stored in an analysis condition information storing section (34). An SIM measurement is conducted according to the parameter that is corrected when analyzing the intended specimen, to thereby make it possible to conduct a desired measurement by an operator.

Abstract: A gas chromatography/mass spectrometry system includes two sample introduction parts, a gas chromatography part having two columns, a column oven for housing the two columns in a parallel configuration, an interface part through which an outlet end of each of the two columns is inserted, and a mass spectrometry part. The mass spectrometry part has an ionization chamber to which the outlet ends of the columns inserted through the interface part are connected, a mass separation part, an ion detector, and a vacuum chamber for housing the ionization chamber, the mass separation part, and the detector. Because the outlet ends of the parallel columns are both connected to the ionization chamber, the carrier gas flow and line velocity are the same as though there is one column, thereby avoiding line stagnation. Since analyses can be performed selectively with a single system, results having high reliability and precision can be obtained.

Abstract: Two sides of a single metal plate are bent to form the structure of a spring terminal having two spring portions. In the spring terminal having such a structure, the two spring portions are different from each other in a natural frequency. For this reason, when external vibrations are applied to a pressure sensor, even if one of the two spring portions of the spring terminal resonates with the external vibrations, the other spring portion can keep the electric connection between a circuit in a substrate and a terminal.

Abstract: A gas chromatography/mass spectrometry system includes two sample introduction parts, a gas chromatography part having two columns, a column oven for housing the two columns in a parallel configuration, an interface part through which an outlet end of each of the two columns is inserted, and a mass spectrometry part. The mass spectrometry part has an ionization chamber to which the outlet ends of the columns inserted through the interface part are connected, a mass separation part, an ion detector, and a vacuum chamber for housing the ionization chamber, the mass separation part, and the detector. Because the outlet ends of the parallel columns are both connected to the ionization chamber, the carrier gas flow and line velocity are the same as though there is one column, thereby avoiding line stagnation. Since analyses can be performed selectively with a single system, results having high reliability and precision can be obtained.

Abstract: In a maintenance system for an analyzing instrument, a maintenance department remotely operates a first computer by a second computer to execute an initial inspection and a basic function inspection of the instrument. Then, an abnormality contained in the result information for every executed inspection is specified, and optimum maintenance information for solving the specified abnormality is searched in a server and extracted. Thereafter, the extracted maintenance information is sent to the first computer in the user side. Namely, an operator at the user side is only required to deal with the maintenance of the instrument in accordance with the maintenance information sent from the maintenance department.

Abstract: In a pressure sensor, a sensor element is mounted on a side of a first surface of a first case, and a second case having a cylindrical hollow portion is bonded to the first case to cover a part of a second surface of the first case, opposite to the first surface. Terminals are embedded in the first case to protrude from the second surface, and branch portions are branched from the terminals from an embedded portion in the first case to have exposed portions exposed to the second surface. A chip capacitor is mounted on the exposed portions on the second surface to be electrically connected to the exposed portions. In the pressure sensor, a diameter (D1) of the second surface of the first case is larger than an inner diameter (D2) of the hollow portion at a position where protrusion top ends of the terminals are positioned.

Abstract: In a pressure sensor, a sensor element is mounted on a side of a first surface of a first case, and a second case having a cylindrical hollow portion is bonded to the first case to cover a part of a second surface of the first case, opposite to the first surface. Terminals are embedded in the first case to protrude from the second surface, and branch portions are branched from the terminals from an embedded portion in the first case to have exposed portions exposed to the second surface. A chip capacitor is mounted on the exposed portions on the second surface to be electrically connected to the exposed portions. In the pressure sensor, a diameter (D1) of the second surface of the first case is larger than an inner diameter (D2) of the hollow portion at a position where protrusion top ends of the terminals are positioned.

Abstract: A tubular insert with a small internal volume is disposed inside the vaporization chamber at the inlet of a capillary column of a gas chromatograph such that the sample with a solvent injected into the vaporization chamber is carried by a carrier gas through the insert into the column. The internal volume of the insert is such that the retention time of the carrier gas through the insert is less than 4 seconds. A heater is controlled to maintain the temperature inside the vaporization chamber within a specified range above the boiling point of the solvent as the sample is injected into the vaporization chamber, and this temperature is subsequently raised to a final temperature above the boiling points of the components to be analyzed. The carrier gas pressure is temporarily increased for better efficiency as the sample is injected.