Patents by Inventor Haruhiko Toda

Haruhiko Toda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7232904
    Abstract: Novel crystals of a potassium salt of (E)-N-[6-methoxy-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl]-2-phenylethenesulfonamide, a preparation process thereof, and novel solvates of (E)-N-[6-methoxy-5-(2-ethoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl]-2-phenylethenesulfonamide.
    Type: Grant
    Filed: July 25, 2002
    Date of Patent: June 19, 2007
    Assignee: Astellas Pharma Inc.
    Inventors: Yoshinori Kato, Hironori Harada, Masahiro Kurotani, Haruhiko Toda, Kenichirou Sakamoto
  • Publication number: 20040162302
    Abstract: Novel crystals of a potassium salt of (E)-N-[6-methoxy-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl]-2-phenylethenesulfonamide, a preparation process thereof, and novel solvates of (E)-N-[6-methoxy-5-(2-ethoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl]-2-phenylethenesulfonamide.
    Type: Application
    Filed: January 26, 2004
    Publication date: August 19, 2004
    Inventors: Yoshinori Kato, Hironori Harada, Masahiro Kurotani, Haruhiko Toda, Kenichirou Sakamoto
  • Patent number: 5849679
    Abstract: A non-ionic surfactant represented by the general formula (1) or (2) shown below, an emulsified composition and a dispersion containing same are disclosed. Also disclosed is a method of preparing glycoside compound having nonionic surface active properties. The nonionic surfactant has good safety to human bodies and is excellent in producing foam with good feeling in touch.General formula ?1!:?Z(OH).sub.q-1 !--O?C.sub.3 H.sub.5 (OH)O!--R.sup.1 ?1!wherein ?Z(OH).sub.q-1 ! stands for a saccharide residue excluding the hydroxyl group connected to the carbon atom in anomeric position among q hydroxyl groups connected to the saccharide compound of the formula ?Z(OH).sub.q !, --O?C.sub.3 H.sub.5 (OH)O!-- for a glycerol residue excluding 2 hydrogen atoms from glycerol HO?C.sub.3 H.sub.5 (OH)O!--H, and R.sup.1 for an aliphatic group having 1-12 carbon atoms,General formula ?2!:?Z(OH).sub.q-1 !--O?C.sub.3 H.sub.5 (OH)O!.sub.x --R.sup.2 ?2!wherein ?Z(OH)!.sub.
    Type: Grant
    Filed: June 13, 1996
    Date of Patent: December 15, 1998
    Assignee: Lion Corporation
    Inventors: Haruhiko Toda, Hiroshi Miyake, Kazuhiko Matsuda, Masahiro Sato
  • Patent number: 5154855
    Abstract: An emulsified composition comprises an oily substance and an emulsifying agent which emulsifies said oily substance in water, characterized in that at least one selected from glucose fatty acid monoesters and alkyl glucoside fatty acid monoesters having 1 to 4 carbon atoms in the alkyl group is used as the emulsifying agent.
    Type: Grant
    Filed: November 13, 1990
    Date of Patent: October 13, 1992
    Assignee: Lion Corporation
    Inventors: Shizuo Sekiguchi, Hiroshi Miyake, Haruhiko Toda
  • Patent number: 5032523
    Abstract: A process for separating an optically active substanbce comprising the steps of:(a) effecting a transesterification reaction between an ester of a linear or branched aliphatic racemic alcohol and an alcohol in an organic solvent containing an enzyme suspended therein; and(b) separating an optically active compound from the resultant reaction mixture.
    Type: Grant
    Filed: January 12, 1988
    Date of Patent: July 16, 1991
    Assignee: Lion Corporation
    Inventors: Masaki Amano, Haruhiko Toda, Minako Yasu, Toshiyuki Koyagi
  • Patent number: 4996158
    Abstract: A racemic alcohol is subjected to the optical resolution by irreversibly esterifying one of the two antipodes of the racemic alcohol with an acid anhydride or enol ester of a carboxylic acid in a organic solvent in the presence of a hydrolase. This optical resolution uses a non-aqueous organic solvent in which the hydrolase is insoluble and involves an irreversible esterification, thus permitting an efficient optical resolution and improving recovery and re-usability of the hydrolase.
    Type: Grant
    Filed: December 21, 1988
    Date of Patent: February 26, 1991
    Inventors: Junichi Oda, Masaki Amano, Haruhiko Toda, Toshiyuki Koyagi
  • Patent number: 4885159
    Abstract: A hair cosmetic composition comprising a polymer vesicle obtained from the polymerization of a surfactant monomer vesicle haing quaternary ammonium as a cation moiety and a polymerizable anion as a counter ion.
    Type: Grant
    Filed: January 28, 1988
    Date of Patent: December 5, 1989
    Assignee: Lion Corporation
    Inventors: Miyuki Miyake, Haruhiko Toda, Minako Yasu
  • Patent number: 4388421
    Abstract: Novel compounds used as polymerizable monomers in a dental adhesive composition, and having a general formula (1): ##STR1## wherein R.sup.2 is a carboxyl group and R.sup.3 is a hydrogen atom when R.sup.1 is a methyl group, and R.sup.2 is a hydroxyl group and R.sup.3 is a carboxyl group when R.sup.1 is a hydrogen atom, that is, N-methyl-N-(2-hydroxy-3-methacryloyloxypropyl)-m-aminobenzoic acid and 2-hydroxy-4-[(2-hydroxy-3-methacryloyloxypropyl)amino]benzoic acid are disclosed.
    Type: Grant
    Filed: December 14, 1981
    Date of Patent: June 14, 1983
    Assignee: Lion Corporation
    Inventors: Shin-ichi Suzuki, Shinya Kitoh, Haruhiko Toda, Moriaki Higo
  • Patent number: 4383052
    Abstract: A novel compound, 1-methacryloxyethane-1,1-diphosphonic acid and its salts provide improved adhesion to tooth substances when used as a polymerizable monomer in a dental adhesive composition.
    Type: Grant
    Filed: December 14, 1981
    Date of Patent: May 10, 1983
    Assignee: Lion Corporation
    Inventors: Moriaki Higo, Yasuo Kikuchi, Shinya Kitoh, Shin-ichi Suzuki, Haruhiko Toda
  • Patent number: 4374292
    Abstract: .alpha.-Thujene is prepared in high yields by isomerizing 1 mole of sabinene with 0.2 to 0.5 moles of an alkali metal, preferably lithium and 0.3 to 0.8 moles of a primary or secondary amine, preferably ethylenediamine. Formation of by-products such as p-cymene is minimized.
    Type: Grant
    Filed: February 3, 1982
    Date of Patent: February 15, 1983
    Assignee: Lion Corporation
    Inventors: Haruhiko Toda, Moriaki Higo, Hitoshi Saga, Masafu Shinbo
  • Patent number: 4162258
    Abstract: Novel compounds trans- and/or cis-spiro[5-isopropylbicyclo[3.1.0]hexane-2,2'-oxiranes], process for the production of the novel compounds comprising reacting 3-isopropyl-2-cyclopenten-1-one with sulfoxonium methylide to form the novel compounds, process for the production of novel compounds comprising reacting 5-isopropylbicyclo[3.1.0]hexan-2-one with sulfonium methylide or sulfoxonium methylide to form the novel compounds, and process for the production of novel compounds comprising the steps of reacting 3-isopropyl-2-cyclopenten-1-one with sulfoxonium methylide to form 5-isopropylbicyclo[3.1.0]hexan-2-one and then reacting the 5-isopropylbicyclo[3.1.0]hexan-2-one with sulfonium methylide or sulfoxonium methylide to form the novel compounds. Trans- and/or cis-sabinene hydrates can readily be prepared from the novel compounds trans- and/or cis-spiro[5-isopropylbicyclo[3.1.0]hexane-2,2'-oxiranes].
    Type: Grant
    Filed: March 27, 1978
    Date of Patent: July 24, 1979
    Assignee: The Lion Dentifrice Co., Ltd.
    Inventors: Moriaki Higo, Haruhiko Toda, Kunitomo Suzuki, Yasukuni Nishida