Abstract: A microcomputer of a light source control device specifies an LED belonging to LEDs and subjected to a short-circuit failure based on a result of determination by a short-circuit failure detecting circuit and current amounts sensed by current sensing circuits respectively. The microcomputer makes corresponding one of switching elements interrupt supply of a current to the specified LED. The microcomputer makes a constant current circuit supply an LED not specified with a current not exceeding a current responsive to the number of such LEDs not specified.

Abstract: The present invention provides a method for screening a therapeutic and/or prophylactic agent for Alzheimer's disease using at least one index selected from the group consisting of the levels of A? oligomers, BiP, cleaved caspase 4, PRDX4 and ROS in nerve cells or the like whose differentiation has been induced from iPS cells derived from somatic cells of a patient with Alzheimer's disease.

Abstract: The present invention provides a prophylactic and/or therapeutic agent for amyotrophic lateral sclerosis, which contains an anacardic acid derivative, and a method of screening for a prophylactic and/or therapeutic drug for amyotrophic lateral sclerosis, utilizing an induced pluripotent stem cell derived from a patient with amyotrophic lateral sclerosis.

Abstract: This invention relates to a vaccine for preventing or treating tautopathy, comprising a vector, as an active ingredient, comprising a nucleic acid encoding a mutant tau protein linked to a secretion signal sequence, wherein the vaccine is capable of inducing an antibody against an (optionally phosphorylated) tau protein in a subject in a more sustained manner compared with a case where the mutant tau protein is administered directly.

Abstract: This invention relates to a vaccine for preventing or treating tautopathy, comprising a vector, as an active ingredient, comprising a nucleic acid encoding a mutant tau protein linked to a secretion signal sequence, wherein the vaccine is capable of inducing an antibody against an (optionally phosphorylated) tau protein in a subject in a more sustained manner compared with a case where the mutant tau protein is administered directly.

Abstract: Provided are a prophylactic and therapeutic agent for amyotrophic lateral sclerosis containing an HMG-CoA reductase inhibitor and a method of screening for a prophylactic and therapeutic drug for amyotrophic lateral sclerosis using an induced pluripotent stem cell derived from a patient with amyotrophic lateral sclerosis.

Abstract: A normal video data acquisition section acquires, as normal video data, a plurality of pieces of video data respectively assigned to a plurality of light sources in normal display from an input video signal A computing section performs a predetermined computation on the plurality of pieces of video data included in the normal video data to generate auxiliary video data used in place of the normal video data in auxiliary display. A selection section performs, in accordance with an instruction from a control section, a selection process for providing any one of the normal video data and the auxiliary video data to a modulation driving section.

Abstract: The present invention provides a method for detecting onset of, or the risk of development of, a protein misfolding disease, and a method for predicting the age of onset of a protein misfolding disease using nerve cells derived from iPS cells. The present invention also provides a kit to be used in these methods.

Abstract: It is intended to provide an agent for regulating axon extension during neuranagenesis by regulating ephrin-Eph receptor signaling mechanisms and to provide a mouse having abnormal ephrin-Eph receptor signaling mechanisms. The present invention relates to a regulator of axon extension, comprising an agent for promoting or suppressing the function of ?-chimerin, and to a miffy (mfy) mouse derived from a B6 strain, which displays autosomal recessive inheritance of an abnormal walking trait exhibiting a hopping gait with left-right synchronized movement of limbs and has mutation in an ?-chimerin gene.

Abstract: It is intended to provide an agent for regulating axon extension during neuranagenesis by regulating ephrin-Eph receptor signaling mechanisms and to provide a mouse having abnormal ephrin-Eph receptor signaling mechanisms. The present invention relates to a regulator of axon extension, comprising an agent for promoting or suppressing the function of ?-chimerin, and to a miffy (mfy) mouse derived from a B6 strain, which displays autosomal recessive inheritance of an abnormal walking trait exhibiting a hopping gait with left-right synchronized movement of limbs and has mutation in an ?-chimerin gene.

Abstract: An object of the present invention is to provide a substrate of Parkin, a system for elucidating the cause of Parkinson's disease using the substrate and a method of screening for a remedy for Parkinson's disease. An animal cell having a DNA encoding a human Pael receptor or a DNA having a variant of the DNA incorporated therein; a non-human mammal having a DNA carrying the aforementioned DNA incorporated therein; a probe comprising the whole or a part of DNA encoding the human Pael receptor; and an antibody specifically recognizing Pael receptor.

Abstract: A low-bed type seismic isolator for a display case, which includes: at least two lines of arcuate X-rails (3) fixed to a lower plate (1) on a foundation and having lower central portions and higher end portions; at least two lines of arcuate Y-rails (4) fixed to a lower surface of an upper plate (2) above the X-rails (3) and having higher central portions and lower end portions in a direction perpendicularly to the X-rails; connection blocks (5) having lower portions clamping the X-rails, upper portions clamping the Y-rails, and a disk spring provided at the central portions thereof; absorbers (8) disposed on the ends of the X-rails and Y-rails and recesses which fixedly accommodates support legs (7) fixed to the lower surface of the upper plate and protruded downwardly from a seismic isolation object.

Abstract: In a magnetic recording/playback apparatus for recording and playing back a digital video signal on a helical track of a magnetic tape using two or more rotary heads, the playback image at the time of high-speed playback is improved by setting the tape travel speed at the time of high-speed playback at an even multiple of a normal playback speed. Further, a tracking phase is offset by one half the track pitch with respect to the tracking during normal speed playback. Alternatively, essential information of the information having been high-efficiency coded is recorded in the central part, and near the ends of the tracks, while high-precision information is recorded in intermediate parts intermediate between the central part and the parts near the ends. Still alternatively, the video data of one of the consecutive fields is recorded in the central part of the tracks and the video data of the other of the consecutive fields is recorded near the ends of the tracks.

Abstract: A digital video signal recording and reproducing apparatus which obtains a favorable reproduced picture even when the data overwritten by edited data is interpolated with the data of the preceding field or preceding frame by recording the video data of the visually inconspicuous peripheral area on a track that is possibly overwritten by the editing data at a cut-in point or cut-out point in assemble editing or insert editing. The apparatus further obtains a natural picture without any fixed error even in speed search mode by exchanging the recording order of the video data of one field on plural tracks according to the head scanning trace in the speed search.

Abstract: In a magnetic recording/playback apparatus for recording and playing back a digital video signal on a helical track of a magnetic tape using two or more rotary heads, the playback image at the time of high-speed playback is improved by setting the tape travel speed at the time of high-speed playback at an even multiple of a normal playback speed. Further a tracking phase is offset by one half the track pitch with respect to the tracking during normal speed playback. Alternatively, essential information of the information having been high-efficiency coded is recorded in the central part, and near the ends of the tracks, while high-precision information is recorded in intermediate parts intermediate between the central part and the parts near the ends. Still alternatively, the video data of one of the consecutive fields is recorded in the central part of the tracks and the video data of the other of the consecutive fields is recorded near the ends of the tracks.