Abstract: A centrifugal separation type FFF device where a rotor can be rotated at a high speed safely so that particles of a smaller size in a sample liquid can be classified. A field flow fractionation device is provided with: a channel that is attached to the inner circumferential surface of the peripheral portion of a rotor and where a classification flow path is created; flow paths for feeding a sample liquid into and out from the classification flow path; and a rotational drive mechanism for rotating the rotational axis, wherein a channel installation portion is formed on one side of the peripheral portion, and a mass balancer portion for adjusting the mass distribution of the rotor is formed on the other side with the rotor base in between.

Abstract: For an easy calibration using calibration particles, provided is a measuring device to capture images of target objects. An image analyzer acquires multiple images obtained at a predetermined time interval, (a) specifies the mean-square displacement of a bright point of a calibration particle based on the displacement of the bright point of the calibration particle in the multiple images in a calibration mode, and (b) specifies the mean-square displacement of a bright point of the target particle based on the displacement of the bright point of the target particle in the multiple images in a measurement mode. A particle size analyzer (c) derives the particle size of the target particle from the mean-square displacement of the bright point of the target particle based on the mean-square displacement of the bright point of the calibration particle and the particle size of the calibration particle in an analysis mode.

Abstract: A wet atomization apparatus includes: a process-target fluid storing container for storing the process-target fluid; a syringe including a gasket configured to be slid on an inner peripheral wall of the syringe by a plunger; a thin tube having one end inserted in the process-target fluid storing container and another end connected to the syringe; and a control section that performs control of the plunger to move forward and backward. Under the control by the control section, an atomization process is performed at least once in which the plunger is moved backward to allow the process-target fluid in the process-target fluid storing container to flow into the syringe via the thin tube so as to be stored in the syringe and the plunger is moved forward to return the process-target fluid stored in the syringe into the process-target fluid storing container via the thin tube.

Abstract: A decoding-side first generation unit generating, for a target unit, a first component prediction sample. A decoding-side linear prediction unit using the first component sample and a prediction coefficient to generate a linear prediction sample of a second component. A decoding-side second generation unit using the second component linear prediction sample to generate, for the target unit, a second component prediction sample. The decoding-side linear prediction unit uses a first coefficient as the prediction coefficient when the first component sample is equal to or below a threshold value, and uses a second coefficient, different from the first, as the prediction coefficient when the first component sample is greater than the threshold value. The threshold value is set on a parameter representing a distribution or change in a reference sample of the first component and/or the second component contained in a reference unit referenced for the target unit.

Abstract: The purpose of the present invention is to provide a particulate observation device using light scattering, which includes a means for determining the three-dimensional position of a particle, and can measure an accurate particle size or impart various properties of same. The present invention is characterized by including a position determination means which captures, with an optical microscope, an image of light scattered from particles in a dispersion medium to which laser light is emitted, and determines a three-dimensional position of each particle from the obtained two dimensional image, wherein the position determination obtains two-dimensional coordinates along the two-dimensional image from luminescent point positions of the particles, and determines the depth position along a coordinate axis vertical to the two-dimensional image from the diameters of diffraction fringes of the luminescent points.

Abstract: Provided is a centrifugal field-flow fractionation device in which a liquid sample is less likely to leak from a channel and attachment and detachment work of a channel member is facilitated. By integrally forming an outer peripheral surface 162 and an inner peripheral surface 163 of a channel member 16, the channel member 16 is configured as one hollow member having a channel 161 formed inside. Thus, pressure resistance performance of the channel member 16 is improved, formation of a gap in the channel 161 can be prevented, and deterioration in sealing performance due to secular change is not generated. Accordingly, a liquid sample is less likely to leak from the channel 161. Further, since the channel member 16 can be handled as one member, attachment and detachment work of the channel member 16 is facilitated.

Abstract: A measuring method enabling simple and accurate measurement of a flow velocity distribution in a flow field inside a flow passage of an optical cell and a particle size-measuring method using the measuring method are provided. Providing a tracer particle of a smaller size than wavelength ? of laser light into the flow passage and capturing a bright spot attributed to light scattering from tracer particles by camera, and obtaining the flow velocity distribution by the analysis unit by obtaining an amount of movement of each tracer particle from movement of the bright spot and correcting a Brownian motion component from a correlation between an average value of variations of the amount of movement and Brownian motion are performed.

Abstract: A centrifugal field-flow fractionation device capable of improving analysis performance and shortening analysis time is provided. A first channel 111 communicating with a channel member is formed on a rotational shaft 11 that rotates together with a rotor. A second channel 644 communicating with the first channel 111 is formed on a fixing portion 60 fixed in a state of facing the rotational shaft 11 along a rotational axis L. A mechanical seal 66 having a pair of seal rings 661 and 662 that come into contact with each other and a biasing member 663 is provided to attach one seal ring 661 to the rotational shaft 11 and the other seal ring 662 to the fixing portion 60. The biasing member 663 biases the pair of seal rings 661 and 662 in a direction in which the pair of seal rings come in contact with each other. Since the rotational shaft 11 can be rotated at a high speed and the liquid sample can be fed at a high pressure, the analysis performance can be improved and the analysis time can be shortened.

Abstract: For an easy calibration using calibration particles, provided is a measuring device to capture images of target objects. An image analyzer acquires multiple images obtained at a predetermined time interval, (a) specifies the mean-square displacement of a bright point of a calibration particle based on the displacement of the bright point of the calibration particle in the multiple images in a calibration mode, and (b) specifies the mean-square displacement of a bright point of the target particle based on the displacement of the bright point of the target particle in the multiple images in a measurement mode. A particle size analyzer (c) derives the particle size of the target particle from the mean-square displacement of the bright point of the target particle based on the mean-square displacement of the bright point of the calibration particle and the particle size of the calibration particle in an analysis mode.

Abstract: Data relating to a particle classified by a centrifugal field flow fractionation device in a preset analysis condition is processed by a data processing apparatus. Inputs of an arbitrary particle diameter and an arbitrary analysis condition are received (Step S101). An elution time of a particle having the particle diameter is calculated based on the input particle diameter and analysis condition (Step S102). The calculated elution time is displayed on a display unit (Step S103).

Abstract: An image decoding device includes a circuit that generates a prediction signal included in a prediction block based on a reference signal included in a reference block. The circuit includes an interpolation filter that generates an interpolation signal of a decimal reference pixel included in the reference block from a reference signal of an integer reference pixel included in the reference block. The circuit selects a type of the interpolation filter based on a block size of the prediction block and a quantization parameter of the prediction block.

Abstract: A decoding-side first generation unit generating, for a target unit, a first component prediction sample. A decoding-side linear prediction unit using the first component sample and a prediction coefficient to generate a linear prediction sample of a second component. A decoding-side second generation unit using the second component linear prediction sample to generate, for the target unit, a second component prediction sample. The decoding-side linear prediction unit uses a first coefficient as the prediction coefficient when the first component sample is equal to or below a threshold value, and uses a second coefficient, different from the first, as the prediction coefficient when the first component sample is greater than the threshold value. The threshold value is set on a parameter representing a distribution or change in a reference sample of the first component and/or the second component contained in a reference unit referenced for the target unit.

Abstract: The purpose of the present invention is to provide a particulate observation device using light scattering, which includes a means for determining the three-dimensional position of a particle, and can measure an accurate particle size or impart various properties of same. The present invention is characterized by including a position determination means which captures, with an optical microscope, an image of light scattered from particles in a dispersion medium to which laser light is emitted, and determines a three-dimensional position of each particle from the obtained two dimensional image, wherein the position determination obtains two-dimensional coordinates along the two-dimensional image from luminescent point positions of the particles, and determines the depth position along a coordinate axis vertical to the two-dimensional image from the diameters of diffraction fringes of the luminescent points.

Abstract: Provided is a particle measuring device and a particle measuring method for measuring a particle size with favorable accuracy. A flow cell (1) includes a flow passage (1a) of sample fluid. An irradiation optical system (3) irradiates, with light from a light source (2), the sample fluid in the flow passage (1a). An imaging unit (4) captures, from an extension direction of the flow passage (1a), an image of scattered light from the particle in a detection region in the flow passage (1a), the light passing through the detection region. A particle size specifying unit specifies a movement amount of the particle in a two-dimensional direction by Brownian motion based on multiple still images of a particle image captured at a predetermined frame rate by the imaging unit (4), thereby specifying the particle size of the particle from the movement amount in the two-dimensional direction.

Abstract: Provided is a centrifugal field-flow fractionation device in which a liquid sample is less likely to leak from a channel and attachment and detachment work of a channel member is facilitated. By integrally forming an outer peripheral surface 162 and an inner peripheral surface 163 of a channel member 16, the channel member 16 is configured as one hollow member having a channel 161 formed inside. Thus, pressure resistance performance of the channel member 16 is improved, formation of a gap in the channel 161 can be prevented, and deterioration in sealing performance due to secular change is not generated. Accordingly, a liquid sample is less likely to leak from the channel 161. Further, since the channel member 16 can be handled as one member, attachment and detachment work of the channel member 16 is facilitated.

Abstract: Provided is a particle measuring device and a particle measuring method for measuring a particle size with favorable accuracy. A flow cell (1) includes a flow passage (1a) of sample fluid. An irradiation optical system (3) irradiates, with light from a light source (2), the sample fluid in the flow passage (1a). An imaging unit (4) captures, from an extension direction of the flow passage (1a), an image of scattered light from the particle in a detection region in the flow passage (1a), the light passing through the detection region. A particle size specifying unit specifies a movement amount of the particle in a two-dimensional direction by Brownian motion based on multiple still images of a particle image captured at a predetermined frame rate by the imaging unit (4), thereby specifying the particle size of the particle from the movement amount in the two-dimensional direction.

Abstract: A measuring method enabling simple and accurate measurement of a flow velocity distribution in a flow field inside a flow passage of an optical cell and a particle size-measuring method using the measuring method are provided.

Abstract: A flow cell for optical measurement capable of accurately measuring light emitted from particles, which is caused by a laser light provided into the flow path. A flow path block having a substantially cuboid shape and made of a transparent material is detachably interposed between a pair of a fluid medium inlet block and a fluid medium outlet block, and a light absorbing surface of the fluid medium inlet block and a light absorbing surface of the fluid medium outlet block are pressed against both end surfaces of the flow path block, respectively. The flow path is provided along a central axis of the flow path block to penetrate through the flow path block between the both end surfaces, and optical windows are detachably provided in outer end opening portions of extended flow paths along the central axis, to seal the outer end opening portions. Inlet and outlet paths for the fluid medium are provided along an introduction axis which intersects the central axis in the vicinity of the outer end opening portions.

Abstract: A centrifugal field-flow fractionation device capable of improving analysis performance and shortening analysis time is provided. A first channel 111 communicating with a channel member is formed on a rotational shaft 11 that rotates together with a rotor. A second channel 644 communicating with the first channel 111 is formed on a fixing portion 60 fixed in a state of facing the rotational shaft 11 along a rotational axis L. A mechanical seal 66 having a pair of seal rings 661 and 662 that come into contact with each other and a biasing member 663 is provided to attach one seal ring 661 to the rotational shaft 11 and the other seal ring 662 to the fixing portion 60. The biasing member 663 biases the pair of seal rings 661 and 662 in a direction in which the pair of seal rings come in contact with each other. Since the rotational shaft 11 can be rotated at a high speed and the liquid sample can be fed at a high pressure, the analysis performance can be improved and the analysis time can be shortened.

Abstract: The invention provides a centrifugal separation type FFF device where a rotor can be rotated at a high speed safely so that particles of a smaller size in a sample liquid can be classified. A field flow fractionation device 11 is provided with: a channel 26 that is attached to the inner circumferential surface 53a of the peripheral portion 53 of a rotor 51 and where a classification flow path 38 is created; flow paths 31, 33, 41, 42, 34, 32 for feeding a sample liquid into and out from the classification flow path 38; and a rotational drive mechanism 28 for rotating the rotational axis 24, wherein a channel installation portion 55 is formed on one side of the peripheral portion 53, and a mass balancer portion 56 for adjusting the mass distribution of the rotor 51 is formed on the other side with the rotor base in between.