Patents by Inventor Haruka SASANO

Haruka SASANO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MUTANT L-PIPECOLIC ACID HYDROXYLASE AND CIS-5-HYDROXY-L-PIPECOLIC ACID PRODUCTION METHOD UTILIZING SAME
    Publication number: 20240043887
    Abstract: The present invention aims to provide a mutant L-pipecolic acid hydroxylase for highly productive and highly selective production of cis-5-hydroxy-L-pipecolic acid by hydroxylation of L-pipecolic acid, and to provide a novel method for industrially producing cis-5-hydroxy-L-pipecolic acid from L-pipecolic acid with high productivity at low cost. The present invention provides a mutant L-pipecolic acid hydroxylase having an amino acid sequence that a particular amino acid mutation(s) is/are introduced in the amino acid sequence of SEQ ID NO:2.
    Type: Application
    Filed: December 24, 2021
    Publication date: February 8, 2024
    Applicant: API CORPORATION
    Inventors: Yasuhisa ASANO, Suguru SHINODA, Junichi ENOKI, Ryoma MIYAKE, Haruka SASANO
  • Method for producing (1R,3R)-3-(trifluoromethyl)cyclohexan-1-ol and intermediate thereof
    Patent number: 11396666
    Abstract: A method for producing a compound represented by formula (3) including bringing a carbon-carbon double bond reductase, a microorganism or cell having an ability to produce the enzyme, a processed product of the microorganism or cell, and/or a culture solution containing the enzyme which is obtained by culturing the microorganism or cell, and a carbonyl reductase, a microorganism or cell having an ability to produce the enzyme, a processed product of the microorganism or cell, and/or a culture solution containing the enzyme which is obtained by culturing the microorganism or cell into contact with a compound represented by formula (1) to obtain a compound represented by formula (3):
    Type: Grant
    Filed: April 17, 2020
    Date of Patent: July 26, 2022
    Assignee: API CORPORATION
    Inventors: Haruka Sasano, Takanobu Iura, Kenji Oki
  • METHOD FOR PRODUCING (1R,3R)-3-(TRIFLUOROMETHYL)CYCLOHEXAN-1-OL AND INTERMEDIATE THEREOF
    Publication number: 20220098623
    Abstract: A method for producing a compound represented by formula (3) including bringing a carbon-carbon double bond reductase, a microorganism or cell having an ability to produce the enzyme, a processed product of the microorganism or cell, and/or a culture solution containing the enzyme which is obtained by culturing the microorganism or cell, and a carbonyl reductase, a microorganism or cell having an ability to produce the enzyme, a processed product of the microorganism or cell, and/or a culture solution containing the enzyme which is obtained by culturing the microorganism or cell into contact with a compound represented by formula (1) to obtain a compound represented by formula (3):
    Type: Application
    Filed: April 17, 2020
    Publication date: March 31, 2022
    Applicant: API CORPORATION
    Inventors: Haruka SASANO, Takanobu IURA, Kenji OKI