Patents by Inventor Haruki Koide

Haruki Koide has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8883462
    Abstract: A triprenyl phenol compound represented by the following formula (II) and (III) and having a thrombolysis-enhancing activity, and an efficient method for producing the triprenyl phenol compound. In formula (II) and (III), R1 represents an aromatic group having as a substituent or as a part of a substituent at least one member selected from the group consisting of a carboxyl group, a hydroxyl group, a sulfonic acid group and a secondary amino group, or an aromatic group which comprises a secondary amino group and may comprise nitrogen; R4 in the general formula (III) represents an aromatic amino acid residue represented by the general formula (III-1) below; X represents —CHY—(CH3)2Z; and Y and Z are respectively —H or —OH or together form a single bond: (III-1) wherein R5 represents a hydroxyl group which may be present or absent; and n represents an integer of 0 or 1.
    Type: Grant
    Filed: January 4, 2012
    Date of Patent: November 11, 2014
    Assignee: Tokyo University of Agriculture and Technology TLO Co., Ltd.
    Inventors: Keiji Hasumi, Yoshikazu Kitano, Hideo Ohishi, Haruki Koide, Keiko Hasegawa, Ritsuko Narasaki
  • Publication number: 20120100579
    Abstract: A triprenyl phenol compound represented by the following formula (II) and (III) and having a thrombolysis-enhancing activity, and an efficient method for producing the triprenyl phenol compound. In formula (II) and (III), R1 represents an aromatic group having as a substituent or as a part of a substituent at least one member selected from the group consisting of a carboxyl group, a hydroxyl group, a sulfonic acid group and a secondary amino group, or an aromatic group which comprises a secondary amino group and may comprise nitrogen; R4 in the general formula (III) represents an aromatic amino acid residue represented by the general formula (III-1) below; X represents —CHY—(CH3)2Z; and Y and Z are respectively —H or —OH or together form a single bond: (III-1) wherein R5 represents a hydroxyl group which may be present or absent; and n represents an integer of 0 or 1.
    Type: Application
    Filed: January 4, 2012
    Publication date: April 26, 2012
    Applicant: TOKYO UNIVERSITY OF AGRICLATURE AND TECHNOLOGY TLO CO., LTD.
    Inventors: Keiji HASUMI, Yoshikazu KITANO, Hideo OHISHI, Haruki KOIDE, Keiko HASEGAWA, Ritsuko NARASAKI
  • Patent number: 8110596
    Abstract: The present invention provides a triprenyl phenol compound represented by the following formula (II) and (III) and having a thrombolysis-enhancing activity, and an efficient method for producing the triprenyl phenol compound. In formula (II) and (III), R1 represents an aromatic group having as a substituent or as a part of a substituent at least one member selected from the group consisting of a carboxyl group, a hydroxyl group, a sulfonic acid group and a secondary amino group, or an aromatic group which comprises a secondary amino group and may comprise nitrogen; R4 in the general formula (III) represents an aromatic amino acid residue represented by the general formula (III-1) below; X represents —CHY—(CH3)2Z; and Y and Z are respectively —H or —OH or together form a single bond: (III-1) wherein R5 represents a hydroxyl group which may be present or absent; and n represents an integer of 0 or 1.
    Type: Grant
    Filed: March 20, 2007
    Date of Patent: February 7, 2012
    Assignee: Tokyo University of Agriculture and Technology TLO Co., Ltd.
    Inventors: Keiji Hasumi, Yoshikazu Kitano, Hideo Ohishi, Haruki Koide, Keiko Hasegawa, Ritsuko Narasaki
  • Publication number: 20090216028
    Abstract: The present invention provides a triprenyl phenol compound represented by the following formula (II) and (III) and having a thrombolysis-enhancing activity, and an efficient method for producing the triprenyl phenol compound. In formula (II) and (III), R1 represents an aromatic group having as a substituent or as a part of a substituent at least one member selected from the group consisting of a carboxyl group, a hydroxyl group, a sulfonic acid group and a secondary amino group, or an aromatic group which comprises a secondary amino group and may comprise nitrogen; R4 in the general formula (III) represents an aromatic amino acid residue represented by the general formula (III-1) below; X represents —CHY—(CH3)2Z; and Y and Z are respectively —H or —OH or together form a single bond: (III-1) wherein R5 represents a hydroxyl group which may be present or absent; and n represents an integer of 0 or 1.
    Type: Application
    Filed: March 20, 2007
    Publication date: August 27, 2009
    Applicant: Tokyo University of Agriculture and Technology TLO Co., LTD.
    Inventors: Keiji Hasumi, Yoshikazu Kitano, Hideo Ohishi, Haruki Koide, Keiko Hasegawa, Ritsuko Narasaki