Patents by Inventor Haruki Shimodaira

Haruki Shimodaira has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isotope-labeled pyrylium compound
    Patent number: 9347949
    Abstract: The present invention provides a compound represented by the formula (I): or a salt thereof; and a method of quantitatively analyzing an amino group-containing target substance, including labeling a target substance in samples by using, as a labeling compound, two or more of such compounds having a mutually different mass due to isotope labeling, to confer a mass difference to the target substance between two or more samples, and the like.
    Type: Grant
    Filed: March 28, 2013
    Date of Patent: May 24, 2016
    Assignees: National University Corporation University of Fukui, Hokuriku University, Taiyo Nippon Sanso Corporation
    Inventors: Shigeru Matsukawa, Kazumi Narita, Yasushi Arakawa, Haruki Shimodaira
  • ISOTOPE-LABELED PYRYLIUM COMPOUND
    Publication number: 20150094233
    Abstract: The present invention provides a compound represented by the formula (I): or a salt thereof; and a method of quantitatively analyzing an amino group-containing target substance, including labeling a target substance in samples by using, as a labeling compound, two or more of such compounds having a mutually different mass due to isotope labeling, to confer a mass difference to the target substance between two or more samples, and the like.
    Type: Application
    Filed: March 28, 2013
    Publication date: April 2, 2015
    Inventors: Shigeru Matsukawa, Kazumi Narita, Yasushi Arakawa, Haruki Shimodaira
  • METHOD FOR MULTIPLE QUANTIFICATION OF AMINO GROUP-CONTAINING NON-PEPTIDIC COMPOUND WITH HIGH EFFICIENCY AND HIGH SENSITIVITY AND KIT THEREFOR
    Publication number: 20120252052
    Abstract: A method of quantifying a target non-peptidic compound having an amino group contained in one or more biological samples, which comprises a step of producing a difference in the mass of the target non-peptidic compound between samples, by using a combination of two or more kinds of stable isotopes of a compound represented by the formula (I): wherein R1, R2 and R3 are the same or different and each is hydrogen, halogen or alkyl, or a salt thereof, as a labeling compound; and a kit and the like usable for such method.
    Type: Application
    Filed: March 30, 2012
    Publication date: October 4, 2012
    Applicants: Taiyo Nippon Sanso Corporation, National University Corporation University of Fukui
    Inventors: Shigeru MATSUKAWA, Kazumi NARITA, Haruki SHIMODAIRA
  • METHOD FOR PRODUCING COMPOUND HAVING DEUTERATED AROMATIC RING OR HETEROCYCLIC RING
    Publication number: 20100331540
    Abstract: A method for producing a compound having a deuterated aromatic ring or heterocyclic ring according to the invention includes heating a compound having an aromatic ring or heterocyclic ring in the presence of heavy water, a transition metal and a metal which generates deuterium. As the metal which generates deuterium, at least one metal selected from the group consisting of aluminum, magnesium, zinc, iron, lead and tin is preferred. As the transition metal, at least one metal selected from the group consisting of platinum, palladium, ruthenium and rhodium is preferred. The heating is preferably carried out by microwave irradiation.
    Type: Application
    Filed: January 30, 2009
    Publication date: December 30, 2010
    Inventors: Haruki Shimodaira, Toshifumi Abe, Akira Miyazawa, Yuji Kawanishi, Taichi Abe