Abstract: A tetrahydronaphthalene derivative of the formula: ##STR1## wherein R.sup.1 is a substituted or unsubstituted phenyl group, naphthyl group, a sulfur- or nitrogen-containing heterocyclic group, a lower alkyl group or cycloalkyl group, and R.sup.2 is hydroxymethyl group, carboxyl group, a lower alkoxycarbonyl group or a group of the formula: ##STR2## wherein R.sup.3 is hydrogen atom or a lower alkyl group, R.sup.

Abstract: The invention relates to aminotetrahydronaphthalene derivatives which are intermediates for the preparation of sulfonylaminotetrahydronaphthalenes.

Abstract: Method for the treatment or prophylaxis of thromboses or asthma in warm-blooded animal which comprises administering an effective amount of a compound having the formula: ##STR1## wherein R.sup.1 is phenyl group or phenyl group substituted by a member selected from the group consisting of C.sub.1 -C.sub.5 alkyl, C.sub.1 -C.sub.5 alkoxy, halogen atom, trifluoromethyl, and nitro, or naphthyl group, and R.sup.2 is hydroxymethyl or a group of the formula: ##STR2## wherein R.sup.3 is hydrogen atom or C.sub.1 -C.sub.5 alkyl and R.sup.4 is C.sub.3 -C.sub.6 cycloalkyl, C.sub.2 -C.sub.6 alkoxycarbonyl-phenyl, carboxy-phenyl, C.sub.1 -C.sub.5 alkyl, or C.sub.1 -C.sub.5 alkyl having a substituent selected from C.sub.1 -C.sub.5 alkoxycarbonyl, carboxy, C.sub.2 -C.sub.6 alkoxycarbonyl-phenyl, carboxy-phenyl, C.sub.2 -C.sub.6 alkoxycarbonyl-(C.sub.3 -C.sub.6) cycloalkyl and carboxy-(C.sub.3 -C.sub.6) cycloalkyl, or a pharmaceutically acceptable salt thereof to said warm blooded animal.

Abstract: Indan derivatives of the formula: ##STR1## wherein R.sup.1 is substituted or unsubstituted phenyl, naphthyl or sulfur-containing heterocyclic group, and R.sup.2 is hydroxy-methyl or a group of the formula: ##STR2## wherein R.sup.3 is hydrogen atom or lower alkyl and R.sup.4 is cycloalkyl, lower alkoxycarbonyl-phenyl, carboxy-phenyl, nitrogen-containing heterocyclic group, lower alkyl, or lower alkyl having a substituent selected from lower alkoxycarbonyl, carboxy, lower alkoxycarbonyl-phenyl, carboxy-phenyl, lower alkoxycarbonyl-cycloalkyl and carboxy-cycloalkyl, or a pharmaceutically acceptable salt thereof, which are useful as a platelet aggregation-inhibiting agent and as an agent for the treatment, amelioration and/or prophylaxis of a variety of thrombosis or embolism, coronary and cerebral vascular smooth muscle vellication, asthma, and the like, processes for the preparation thereof, and pharmaceutical composition containing said compound as an active ingredient.

Abstract: Novel indanoxyacetic acid derivatives of the formula: ##STR1## wherein R.sup.1 is a lower alkyl group, a substituted or unsubstituted phenyl group, naphtyl group or a sulfur-containing heterocyclic group, R.sup.2 is hydroxy group or a protected hydroxy group, p is an integer of 2 or 3, and q is an integer of 0 or 1, and a salt thereof are disclosed.Said derivative (I) and a salt thereof are useful as a platelet aggregation-inhibiting agent and an agent for the treatment, amelioration and/or prophylaxis of a variety of thrombosis, embolism, coronary and cerebral vascular smooth muscl vellication, asthma, and the like.