Abstract: The present invention aims to develop and provide a method for identifying a disease associated with the abundance of TDP-43 in cells and a method for producing a TDP-43 binding inhibitor. By measuring the abundance of a measurement substance, the amount of binding between a measurement substance and TDP-43, etc. in cells obtained from a subject, it is identified whether or not the subject is suffering from a disease associated with the abundance of TDP-43 in cells. Also, a drug which can significantly reduce the binding between a measurement substance and TDP-43 is produced by adding a drug candidate substance.

Abstract: A modem is disclosed having a data transmission protocol involving lower-speed, full-duplex operation during the connect sequence with a remote modem and an automatic switch to higher-speed, half-duplex operation for data transfer. Further, the modem data transmission involves transparently changing between lower-speed, interactive operation and higher-speed operation based upon data transmission demands. The operation is controlled by a processor monitoring the contents of a transmit data buffer and providing a mode control command to the modem transmitter. The modem also adapts its speed to the quality of the telephone line by fallback or fallforward to a different speed based upon predetermined data frame retransmission criteria.

Abstract: A modem is disclosed having a data transmission protocol involving lower-speed, full-duplex operation during the connect sequence with a remote modem and an automatic switch to higher-speed, half-duplex operation for data transfer. Further, the modem data transmission involves transparently changing between lower-speed, interactive operation and higher-speed operation based upon transmission demands. The operation is controlled by a processor monitoring the contents of a transmit data buffer and providing a mode control command to the modem transmitter. The modem also adapts its speed to the quality of the telephone line by fallback or fallforward to a different speed based upon predetermined data frame retransmission criteria.

Abstract: A serial printer comprises a carriage, a print member rotatably mounted to the carriage and including a plurality of character elements, a drive coupled to the print member for rotating the print member to a desired rotational position, a device coupled to the print member for generating a plurality of periodic position signals each indicative of the rotational movement of the print member, and a device for storing a count indicative of the actual rotational position of the print member, the device for storing including a device responsive to an increment pulse for incrementing the count by one and a device responsive to a decrement pulse for decrementing the count by one.