Abstract: A process for producing water-insoluble substances derived from fishes and shellfishes, includes the treating of the waste of fishes and shellfishes containing the substances with proteolytic enzymes under stirring to obtain an oil-in-water (O/W) type emulsified composition. This composition contains water-soluble amino-acids, oligoproteins having a molecular weight of not greater than 30,000, water-soluble minerals, water-insoluble highly unsaturated fatty acids and proteins (solid matter) having a molecular weight of 20,000 to 100,000, with 50% or more of all the proteins in said emulsified composition having a molecular weight of 20,000 to 100,000. Thereafter the emulsified composition is separated into solid and liquid phases, and the obtained solid composition containing proteins with a molecular weight of 20,000 to 100,000 and fats and oils is extracted with an organic solvent.

Abstract: The present invention is to provide feed which is taken well by animals and marine animals, promotes the growth of the body and bone, relieves symptoms of a chicken coccidium disease, and has the effect of substituting low-priced soybean oil meal for fish meal, and if feed containing a precipitated fraction itself or after concentrated and dried, which was prepared by subjecting one or more bodies selected from marine animals, treated materials thereof or separated materials therefrom to enzymatic treatment with a proteolytic enzyme, is used, then the intake of the feed by domestic animals and raised marine animals is increased to promote the growth of bone, thus accelerating their growth and promoting an increase in their body weight, and preventing or relieving the chicken coccidium disease.