Abstract: A novel compound, a novel ?1 adrenergic receptor antagonistic agent, and a novel composition are provided which are capable of exerting a therapeutic effect on treatment of hypertension as well as treatment of prostatic hypertrophy and the like.

Abstract: A muscle-strengthening, anti-inflammatory, antiasthmatic, antidiarrheal or an antidepressant method, or a method for the treatment of diminution of vision, hepatitis, inflammatory intestinal syndrome, functional enteropathy, functional hepatopathy, functional nephropathy, dementia, climacteric symptoms, senile dementia and/or Alzheimer disease, said method comprising: administering to skin a composition comprising (a) at least one member selected from the group consisting of isoflavones and isoflavone glycosides, (b) curcumin, and (c) cholic acid or at least one member selected from the group consisting of scymnol and scymnol esters.

Abstract: A novel compound, a novel ?1 adrenergic receptor antagonistic agent, and a novel composition are provided which are capable of exerting a therapeutic effect on treatment of hypertension as well as treatment of prostatic hypertrophy and the like.

Abstract: The present invention relates to novel flavone C-glycoside derivatives or salts thereof, especially those showing an anti-allergic effect, and compositions containing them. Recently, cases of allergic diseases, especially pollenosis and atopic dermatitis have increased to such a degree that they have become a social problem. Flavones and their glycosides have been reported to have the effect of inhibiting histamine release from mast cells or an immunosuppressive effect and expected for application as allergy therapies. However, most flavones exhibit their effects only at high doses, so that effective compounds at lower doses are highly desired. The present invention provides novel components capable of treating allergic diseases at low doses and compositions containing them.

Abstract: It is intended to provide a process for efficiently producing a flavone C glycoside derivative represented by the formula (1) which is an antiallergic substance or its salt, or a flavone C glycoside derivative represented by the formula (4) or its salt. According to this process, the flavone C glycoside derivative represented by the formula (1) or its salt and the flavone C glycoside derivative represented by the formula (4) can be easily and efficiently synthesized by using isovitexine and vitexine contained in herbs and so on as the starting materials.

Abstract: A muscle-strengthening, anti-inflammatory, antiasthmatic, antidiarrheal or an antidepressant method, or a method for the treatment of diminution of vision, hepatitis, inflammatory intestinal syndrome, functional enteropathy, functional hepatopathy, functional nephropathy, dementia, climacteric symptoms, senile dementia and/or Alzheimer disease, said method comprising: administering to skin a composition comprising (a) at least one member selected from the group consisting of isoflavones and isoflavone glycosides, (b) curcumin, and (c) cholic acid or at least one member selected from the group consisting of scymnol and scymnol esters.

Abstract: The present invention relates to novel flavone C-glycoside derivatives or salts thereof, especially those showing an anti-allergic effect, and compositions containing them. Recently, cases of allergic diseases, especially pollenosis and atopic dermatitis have increased to such a degree that they have become a social problem. Flavones and their glycosides have been reported to have the effect of inhibiting histamine release from mast cells or an immunosuppressive effect and expected for application as allergy therapies. However, most flavones exhibit their effects only at high doses, so that effective compounds at lower doses are highly desired. The present invention provides novel components capable of treating allergic diseases at low doses and compositions containing them.

Abstract: A substance capable of stimulating the movement of digestive tract, comprising a compound of the formula: (I) (active substance ? and active substance ? being stereoisomers), which substance is derived from natural products and hence cause no side effects, is highly safe even when continuously used for a prolonged period of time and can be widely employed as additives to refreshments, etc.; and a refreshment containing an additive comprising the stimulating substance. In particular, a digestive tract movement stimulating substance capable of acting on muscarine M3 receptor, obtained from beer through isolation and purification, which substance is one having drinkability stimulating effect; and a composition from natural products or natural processed products, comprising the above substance. The thus provided substance or composition is used as an additive to refreshment, thereby providing a refreshment capable of stimulating the movement of digestive tract.

Abstract: An object of the present invention is to provide a pharmaceutical agent or composition useful as a muscle-strengthening drug, an anti-inflammatory drug, an antiasthmatic, an antidiarrheal, an antidepressant, or a drug for the treatment of secondary diseases following cerebral infarction, motor paralysis, diminution of vision, hepatitis, inflammatory intestinal syndrome, functional enteropathy, functional cardiopathy, functional hepatopathy, functional nephropathy, dementia, climacteric symptoms, senile dementia and/or Alzheimer disease, and a dermatological agent or composition suitable for skin applications, which can treat or prevent muscle weakening and inflammation, in particular arthritis, by its muscle-strengthening and/or anti-inflammatory actions, said agent or composition comprising isoflavone and/or isoflavone glycoside in combination with a pungent substance, a bitter substance or a sour substance, and cholic acid, and/or scymnol and/or a scymnol ester.

Abstract: A crystallized, stable histidine-hydrogen peroxide adduct intermolecular-bonded at 1:1 ratio is provided.