Patents by Inventor Harutami Yamada

Harutami Yamada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of Parkinson's disease and enhancement of dopamine signal using PDE 10 inhibitor
    Patent number: 8338420
    Abstract: The present invention relates to a therapeutic or prophylactic method for treating Parkinson's disease by administering an effective amount of a compound having a phosphodiesterase 10 inhibitory activity; and also relates to a pharmaceutical composition for treatment or prophylaxis of Parkinson's disease comprising as an active ingredient a compound having a phosphodiesterase 10 inhibitory activity. Moreover, the present invention relates to a method for enhancing dopamine signal in the brain, which comprises administering an effective amount of a compound having a phosphodiesterase 10 inhibitory activity; and also relates to pharmaceutical composition for enhancing dopamine signal in brain comprising as an active ingredient a compound having a phosphodiesterase 10 inhibitory activity.
    Type: Grant
    Filed: December 28, 2009
    Date of Patent: December 25, 2012
    Assignee: Mitsubishi Tanabe Pharma Corporation
    Inventors: Jun Kotera, Takashi Sasaki, Takeo Kitazawa, Taketoshi Ishii, Hiroshi Morimoto, Harutami Yamada
  • Pyridazinone derivatives and processes for preparing the same
    Patent number: 5808065
    Abstract: Disclosed is a pyridazinone compound represented by the formula (I): ##STR1## wherein X represents hydrogen atom or the like; Y represents a single bonding arm, oxygen atom or sulfur atom; A represents a straight or branched alkylene group which may have a double bond;B represents carbonyl group or thiocarbonyl group; and R.sup.2 represents an alkyl group having 1 to 10 carbon atoms which may be substituted or the like; orB represents sulfonyl group; and R.sup.2 represents a lower alkenyl group or the like;R.sup.1 represents hydrogen atom or the like; R.sup.3 represents hydrogen atom or the like; R.sup.4 represents hydrogen atom or the like; and R.sup.5 represents hydrogen atom or the like,or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: August 25, 1997
    Date of Patent: September 15, 1998
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Akihiko Ishida, Harutami Yamada, Michihisa Yato, Shinsuke Nishiyama, Fumikazu Okumura
  • Pyridazinone derivatives and processes for preparing the same
    Patent number: 5698554
    Abstract: Disclosed is a pyridazinone compound represented by the formula (I): ##STR1## wherein X represents hydrogen atom or the like; Y represents a single bonding arm, oxygen atom or sulfur atom; A represents a straight or branched alkylene group which may have a double bond;B represents carbonyl group or thiocarbonyl group; and R.sup.2 represents an alkyl group having 1 to 10 carbon atoms which may be substituted or the like; orB represents sulfonyl group; and R.sup.2 represents a lower alkenyl group or the like;R.sup.1 represents hydrogen atom or the like; R.sup.3 represents hydrogen atom or the like; R.sup.4 represents hydrogen atom or the like; and R.sup.5 represents hydrogen atom or the like,or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: June 27, 1996
    Date of Patent: December 16, 1997
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Akihiko Ishida, Harutami Yamada, Michihisa Yato, Shinsuke Nishiyama, Fumikazu Okumura