Patents by Inventor Haruyoshi Arai

Haruyoshi Arai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • &bgr;,&ggr;-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound
    Patent number: 6288128
    Abstract: A &bgr;,&ggr;-dihydropolyprenyl alcohol derivative having the formula: wherein n is an integer of 5 to 7 and R is hydrogen, a lower alkyl group or an aliphatic or aromatic acyl group, is new and useful as a prophylactic therapeutic agent for human and animal immuno-deficiency deseases and phylactic agent against human and animal infectious deseases. Another disclosed polyprenyl compound is also useful as the same agent.
    Type: Grant
    Filed: February 14, 1996
    Date of Patent: September 11, 2001
    Assignee: Eisai Co., Ltd.
    Inventors: Masaichi Yamamoto, Seiichi Araki, Hiroshi Yamamoto, Isao Yamatsu, Takeshi Suzuki, Akiharu Kajiwara, Yoshikazu Suzuki, Haruyoshi Arai
  • Beta, gamma-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound
    Patent number: 6111131
    Abstract: A .beta.,.gamma.-dihydropolyprenyl alcohol derivative having the formula: ##STR1## wherein n is an integer of 5 to 7 and R is hydrogen, a lower alkyl group or an aliphatic or aromatic acyl group, is new and useful as a prophylactic therapeutic agent for human and animal immuno-deficiency deseases and phylactic agent against human and animal infectious deseases. Another disclosed polyprenyl compound is also useful as the same agent.
    Type: Grant
    Filed: January 11, 1996
    Date of Patent: August 29, 2000
    Assignee: Eisai Co., Ltd.
    Inventors: Masaichi Yamamoto, Seiichi Araki, Hiroshi Yamamoto, Isao Yamatsu, Takeshi Suzuki, Akiharu Kajiwara, Yoshikazu Suzuki, Haruyoshi Arai
  • .beta., .gamma.-dihydropolyprenyl alcohol derivatives effective at mitigating stress in animals
    Patent number: 5658958
    Abstract: Various .beta.,.gamma.-dihydropolyprenyl alcohol derivatives having the formula: ##STR1## wherein n is an integer of 5 to 7 and R is hydrogen, a lower alkyl group or an aliphatic or aromatic acyl group are effective at pritigating stress in animals.
    Type: Grant
    Filed: February 14, 1996
    Date of Patent: August 19, 1997
    Assignee: Eisai Co., Ltd.
    Inventors: Masaichi Yamamoto, Seiichi Araki, Hiroshi Yamamoto, Isao Yamatsu, Takeshi Suzuki, Akiharu Kajiwara, Yoshikazu Suzuki, Haruyoshi Arai
  • .beta.,.gamma.-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound
    Patent number: 5280048
    Abstract: A .beta.,.gamma.-dihydropolyprenyl alcohol derivative having the formula: ##STR1## wherein n is an integer of 5 to 7 and R is hydrogen, a lower alkyl group or an aliphatic or aromatic acyl group, is new and usrful as a prophylactic therapeutic agent for human and animal immuno-deficiency deseases and phylactic agent against human and animal infectious deseases. Another disclosed polyprenyl compound is also useful as the same agent.
    Type: Grant
    Filed: January 29, 1993
    Date of Patent: January 18, 1994
    Assignee: Eisai Co., Ltd.
    Inventors: Masaichi Yamamoto, Seiichi Araki, Hiroshi Yamamoto, Isao Yamatsu, Takeshi Suzuki, Akiharu Kajiwara, Yoshikazu Suzuki, Haruyoshi Arai
  • .beta.,.gamma.-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound
    Patent number: 4624966
    Abstract: A .beta.,.gamma.-dihydropolyprenyl alcohol derivative having the formula: ##STR1## wherein n is an integer of 5 to 7 and R is hydrogen, a lower alkyl group or an aliphatic or aromatic acyl group, is new and useful as a phylactic agent against human and animal infectious diseases. Other disclosed polyprenyl compounds are also useful as such agents.
    Type: Grant
    Filed: July 29, 1985
    Date of Patent: November 25, 1986
    Assignee: Eisai Co., Ltd.
    Inventors: Masaichi Yamamoto, Seiichi Araki, Hiroshi Yamamoto, Isao Yamatsu, Takeshi Suzuki, Akiharu Kajiwara, Yoshikazu Suzuki, Haruyoshi Arai
  • Immunopotentiator containing recin
    Patent number: 4459287
    Abstract: An immunopotentiator comprising ricin as an active ingredient. Ricin is a glucoprotein having a molecular weight of about 65,000 and can be used in the form of an aqueous solution. It is useful for prevention and treatment of bacterial and viral infections and cancer.
    Type: Grant
    Filed: June 17, 1982
    Date of Patent: July 10, 1984
    Assignee: Eisai Co., Ltd.
    Inventors: Hiroshi Shionoya, Haruyoshi Arai, Nozomu Koyanagi, Hitoshi Takeuchi
  • Immunopotentiator containing abrin
    Patent number: 4414201
    Abstract: An immunopotentiator comprising abrin as an active ingredient. Abrin is a glucoprotein having a molecular weight of about 65,000 and can be used in the form of an aqueous solution. It is useful for prevention and treatment of bacterial and viral infections.
    Type: Grant
    Filed: June 1, 1982
    Date of Patent: November 8, 1983
    Assignee: Eisai Co., Ltd.
    Inventors: Hiroshi Shionoya, Haruyoshi Arai, Nozomu Koyanagi, Hitoshi Takeuchi
  • 5-Fluorouracil derivatives and antitumor preparations containing the same
    Patent number: 4130648
    Abstract: Novel 5-fluorouracil derivatives of the general formula: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 each represent hydrogen atom or methyl group, and R.sub.4 represents a straight or branched alkyl or alkenyl group, which has low toxicity and improved antitumor activity, and novel antitumor preparations containing the said 5-fluorouracil derivative.
    Type: Grant
    Filed: December 14, 1977
    Date of Patent: December 19, 1978
    Assignee: Eisai Co., Ltd.
    Inventors: Shizumasa Kijima, Hiroshi Shionoya, Kimio Hamamura, Haruyoshi Arai, Nozomu Koyanagi