Patents by Inventor Harvey D. Benson

Harvey D. Benson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4317818
    Abstract: Compounds of the following general formula are useful in treating prostatic carcinoma: ##STR1## wherein R is --CHO or --CH.sub.2 OR.sub.1 ; each of R.sub.1 and R.sub.2 is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 20 carbon atoms and is straight or branched, benzoyl, phenylalkylcarbonyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched or cycloalkylcarbonyl wherein the cycloalkyl moiety has from 5 to 10 carbon atoms; R.sub.3 is hydrogen; or R.sub.2 and R.sub.3 together form a double bond between the 17-position carbon atom and the oxygen atom.
    Type: Grant
    Filed: May 28, 1980
    Date of Patent: March 2, 1982
    Assignee: Richardson-Merrell Inc.
    Inventors: Harvey D. Benson, Joyce F. Grunwell, John O. Johnston, Vladimir Petrow
  • Patent number: 4096254
    Abstract: Compounds of the following general formula are useful in treating the symptoms of menopause and osteoporosis: ##STR1## wherein R is --CHO or --CH.sub.2 OR.sub.1 ; each of R.sub.1 and R.sub.2 is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 20 carbon atoms and is straight or branched, benzoyl, phenylalkylcarbonyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched or cycloalkylcarbonyl wherein the cycloalkyl moiety has from 5 to 10 carbon atoms; R.sub.3 is hydrogen; or R.sub.2 and R.sub.3 together form a double bond between the 17-position carbon atom and the oxygen atom.
    Type: Grant
    Filed: February 22, 1977
    Date of Patent: June 20, 1978
    Assignee: Richardson-Merrell Inc.
    Inventors: Harvey D. Benson, Joyce Francis Grunwell, John O'Neal Johnston, Vladimir Petrow
  • Patent number: 4088760
    Abstract: Compounds of the following general formula are testosterone 5.alpha.-reductase inhibitors rendering said compounds useful in the treatment of acne and oily skin: ##STR1## wherein n is an integer of from 0 to 4; R.sub.1 is --COOR.sub.2, --CONR.sub.3 R.sub.4, --CHO or --CH.sub.2 OR.sub.5 ; R.sub.2 is hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, or benzyl; each of R.sub.3 and R.sub.4 is hydrogen or a straight or branched lower alkyl group of from 1 to 4 carbon atoms; and R.sub.5 is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 20 carbon atoms and is straight or branched, benzoyl, phenylalkylcarbonyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched, or cycloalkylcarbonyl wherein the cycloalkyl moiety has from 5 to 10 carbon atoms.
    Type: Grant
    Filed: June 23, 1976
    Date of Patent: May 9, 1978
    Assignee: Richardson-Merrell Inc.
    Inventors: Harvey D. Benson, Thomas R. Blohm
  • Patent number: 4078061
    Abstract: Compounds of the following general formula are useful in treating acne: ##STR1## wherein R is --CHO or --CH.sub.2 OR.sub.1 ; each of R.sub.1 and R.sub.2 is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 20 carbon atoms and is straight or branched, benzoyl, phenylalkylcarbonyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched or cycloalkylcarbonyl wherein the cycloalkyl moiety has from 5 to 10 carbon atoms; R.sub.3 is hydrogen; or R.sub.2 and R.sub.3 together form a double bond between the 17- position carbon atom and the oxygen atom.
    Type: Grant
    Filed: May 10, 1976
    Date of Patent: March 7, 1978
    Assignee: Richardson-Merrell Inc.
    Inventors: Harvey D. Benson, Joyce Francis Grunwell, John O'Neal Johnston, Vladimir Petrow
  • Patent number: 4078060
    Abstract: Compounds of the following general formula are useful in inducing an estrogenic response in a patient in need thereof: ##STR1## wherein R is --CHO or --CH.sub.2 OR.sub.1 ; each of R.sub.1 and R.sub.2 is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 20 carbon atoms and is straight or branched, benzoyl, phenylalkylcarbonyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched or cycloalkylcarbonyl wherein the cycloalkyl moiety has from 5 to 10 carbon atoms; R.sub.3 is hydrogen; or R.sub.2 and R.sub.3 together form a double bond between the 17-position carbon atom and the oxygen atom.
    Type: Grant
    Filed: May 10, 1976
    Date of Patent: March 7, 1978
    Assignee: Richardson-Merrell Inc.
    Inventors: Harvey D. Benson, Joyce Francis Grunwell, John O'Neal Johnston, Vladimir Petrow
  • Patent number: 4055641
    Abstract: Compounds of the following general formula are useful in treating benign prostatic hypertrophy: ##STR1## wherein R is --CHO or --CH.sub.2 OR.sub.1 ; each of R.sub.1 and R.sub.2 is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 20 carbon atoms and is straight or branched, benzoyl, phenylalkylcarbonyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched or cycloalkylcarbonyl wherein the cycloalkyl moiety has from 5 to 10 carbon atoms; R.sub.3 is hydrogen; or R.sub.2 and R.sub.3 together form a double bond between the 17-position carbon atom and the oxygen atom.
    Type: Grant
    Filed: May 10, 1976
    Date of Patent: October 25, 1977
    Assignee: Richardson-Merrell Inc.
    Inventors: Harvey D. Benson, Joyce Francis Grunwell, John O'Neal Johnston, Vladimir Petrow
  • Patent number: 4054651
    Abstract: A method of contraception which comprises administering a compound of the following general formula: ##STR1## wherein R is --CHO or --CH.sub.2 OR.sub.1 ; each of R.sub.1 and R.sub.2 is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 20 carbon atoms and is straight or branched, benzoyl, phenylalkylcarbonyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched or cycloalkylcarbonyl wherein the cycloalkyl moiety has from 5 to 10 carbon atoms; R.sub.3 is hydrogen; or R.sub.2 and R.sub.3 together form a double bond between the 17-position carbon atom and the oxygen atom either alone or in combination with a progestogen.
    Type: Grant
    Filed: May 10, 1976
    Date of Patent: October 18, 1977
    Assignee: Richardson-Merrell Inc.
    Inventors: Harvey D. Benson, Joyce Francis Grunwell, John O'Neal Johnston, Vladimir Petrow
  • Patent number: 4013762
    Abstract: A method of promoting the growth of ruminants and poultry without concommitant adrogenizing effects using the following compound: ##STR1## wherein R is --CHO or --CH.sub.2 OR.sub.1 ; each of R.sub.1 and R.sub.2 is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 20 carbon atoms and is straight or branched, benzoyl, phenylalkylcarbonyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched or cycloalkylcarbonyl wherein the cycloalkyl moiety has from 5 to 10 carbon atoms; R.sub.3 is hydrogen; or R.sub.2 and R.sub.3 together form a double bond between the 17- position carbon atom and the oxygen atom.
    Type: Grant
    Filed: May 10, 1976
    Date of Patent: March 22, 1977
    Assignee: Richardson-Merrell Inc.
    Inventors: Harvey D. Benson, Joyce Francis Grunwell, John O'Neal Johnston, Vladimir Petrow
  • Patent number: 4000273
    Abstract: 7.alpha.-Methylestr-4-ene-3.alpha.,17.beta.-diol and derivatives thereof useful as antifertility agents.
    Type: Grant
    Filed: October 9, 1975
    Date of Patent: December 28, 1976
    Assignee: Richardson-Merrell Inc.
    Inventors: Joyce F. Grunwell, Harvey D. Benson