Patents by Inventor Harvey L. Kasdan

Harvey L. Kasdan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11946848
    Abstract: For analyzing a sample containing particles of at least two categories, such as a sample containing blood cells, a particle counter subject to a detection limit is coupled with an analyzer capable of discerning particle number ratios, such as a visual analyzer, and a processor. A first category of particles can be present beyond detection range limits while a second category of particles is present within respective detection range limits. The concentration of the second category of particles is determined by the particle counter. A ratio of counts of the first category to the second category is determined on the analyzer. The concentration of particles in the first category is calculated on the processor based on the ratio and the count or concentration of particles in the second category.
    Type: Grant
    Filed: November 9, 2022
    Date of Patent: April 2, 2024
    Assignee: Iris International, Inc.
    Inventors: Thomas H. Adams, Bart J. Wanders, John Roche, Harvey L. Kasdan
  • Publication number: 20230243731
    Abstract: For analyzing a sample containing particles of at least two categories, such as a sample containing blood cells, a particle counter subject to a detection limit is coupled with an analyzer capable of discerning particle number ratios, such as a visual analyzer, and a processor. A first category of particles can be present beyond detection range limits while a second category of particles is present within respective detection range limits. The concentration of the second category of particles is determined by the particle counter. A ratio of counts of the first category to the second category is determined on the analyzer. The concentration of particles in the first category is calculated on the processor based on the ratio and the count or concentration of particles in the second category.
    Type: Application
    Filed: April 11, 2023
    Publication date: August 3, 2023
    Inventors: Thomas H. Adams, Bart J. Wanders, John Roche, Harvey L. Kasdan
  • Publication number: 20230152203
    Abstract: For analyzing a sample containing particles of at least two categories, such as a sample containing blood cells, a particle counter subject to a detection limit is coupled with an analyzer capable of discerning particle number ratios, such as a visual analyzer, and a processor. A first category of particles can be present beyond detection range limits while a second category of particles is present within respective detection range limits. The concentration of the second category of particles is determined by the particle counter. A ratio of counts of the first category to the second category is determined on the analyzer. The concentration of particles in the first category is calculated on the processor based on the ratio and the count or concentration of particles in the second category.
    Type: Application
    Filed: November 9, 2022
    Publication date: May 18, 2023
    Inventors: Thomas H. Adams, Bart J. Wanders, John Roche, Harvey L. Kasdan
  • Patent number: 11525766
    Abstract: For analyzing a sample containing particles of at least two categories, such as a sample containing blood cells, a particle counter subject to a detection limit is coupled with an analyzer capable of discerning particle number ratios, such as a visual analyzer, and a processor. A first category of particles can be present beyond detection range limits while a second category of particles is present within respective detection range limits. The concentration of the second category of particles is determined by the particle counter. A ratio of counts of the first category to the second category is determined on the analyzer. The concentration of particles in the first category is calculated on the processor based on the ratio and the count or concentration of particles in the second category.
    Type: Grant
    Filed: August 6, 2019
    Date of Patent: December 13, 2022
    Assignee: Iris International, Inc.
    Inventors: Thomas H. Adams, Bart J. Wanders, John Roche, Harvey L. Kasdan
  • Publication number: 20200033249
    Abstract: For analyzing a sample containing particles of at least two categories, such as a sample containing blood cells, a particle counter subject to a detection limit is coupled with an analyzer capable of discerning particle number ratios, such as a visual analyzer, and a processor. A first category of particles can be present beyond detection range limits while a second category of particles is present within respective detection range limits. The concentration of the second category of particles is determined by the particle counter. A ratio of counts of the first category to the second category is determined on the analyzer. The concentration of particles in the first category is calculated on the processor based on the ratio and the count or concentration of particles in the second category.
    Type: Application
    Filed: August 6, 2019
    Publication date: January 30, 2020
    Inventors: Thomas H. Adams, Bart J. Wanders, John Roche, Harvey L. Kasdan
  • Patent number: 10429292
    Abstract: For analyzing a sample containing particles of at least two categories, such as a sample containing blood cells, a particle counter subject to a detection limit is coupled with an analyzer capable of discerning particle number ratios, such as a visual analyzer, and a processor. A first category of particles can be present beyond detection range limits while a second category of particles is present within respective detection range limits. The concentration of the second category of particles is determined by the particle counter. A ratio of counts of the first category to the second category is determined on the analyzer. The concentration of particles in the first category is calculated on the processor based on the ratio and the count or concentration of particles in the second category.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: October 1, 2019
    Assignee: Iris International, Inc.
    Inventors: Thomas H. Adams, Bart J. Wanders, John Roche, Harvey L. Kasdan
  • Patent number: 9757729
    Abstract: Described herein are particular embodiments relating to a microfluidic device that may be utilized for cell sensing, counting, and/or sorting. Particular aspects relate to a microfabricated device that is capable of differentiating single cell types from dense cell populations. One particular embodiment relates a device and methods of using the same for sensing, counting, and/or sorting leukocytes from whole, undiluted blood samples.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: September 12, 2017
    Assignee: California Institute of Technology
    Inventors: Yu-Chong Tai, Siyang Zheng, Jeffrey Chun-Hui Lin, Harvey L. Kasdan
  • Publication number: 20170136463
    Abstract: Described herein are particular embodiments relating to a microfluidic device that may be utilized for cell sensing, counting, and/or sorting. Particular aspects relate to a microfabricated device that is capable of differentiating single cell types from dense cell populations. One particular embodiment relates a device and methods of using the same for sensing, counting, and/or sorting leukocytes from whole, undiluted blood samples.
    Type: Application
    Filed: November 18, 2016
    Publication date: May 18, 2017
    Applicant: California Institute of Technology
    Inventors: Yu-Chong Tai, Siyang Zheng, Jeffrey Chun-Hui Lin, Harvey L. Kasdan
  • Patent number: 9535059
    Abstract: Described herein are particular embodiments relating to a microfluidic device that may be utilized for cell sensing, counting, and/or sorting. Particular aspects relate to a microfabricated device that is capable of differentiating single cell types from dense cell populations. One particular embodiment relates a device and methods of using the same for sensing, counting, and/or sorting leukocytes from whole, undiluted blood samples.
    Type: Grant
    Filed: November 3, 2015
    Date of Patent: January 3, 2017
    Assignee: California Institute of Technology
    Inventors: Yu-Chong Tai, Siyang Zheng, Jeffrey Chun-Hui Lin, Harvey L. Kasdan
  • Publication number: 20160131640
    Abstract: Described herein are particular embodiments relating to a microfluidic device that may be utilized for cell sensing, counting, and/or sorting. Particular aspects relate to a microfabricated device that is capable of differentiating single cell types from dense cell populations. One particular embodiment relates a device and methods of using the same for sensing, counting, and/or sorting leukocytes from whole, undiluted blood samples.
    Type: Application
    Filed: November 3, 2015
    Publication date: May 12, 2016
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Yu-Chong Tai, Siyang Zheng, Jeffrey Chun-Hui Lin, Harvey L. Kasdan
  • Patent number: 9234884
    Abstract: Described herein are particular embodiments relating to a microfluidic device that may be utilized for cell sensing, counting, and/or sorting. Particular aspects relate to a microfabricated device that is capable of differentiating single cell types from dense cell populations. One particular embodiment relates a device and methods of using the same for sensing, counting, and/or sorting leukocytes from whole, undiluted blood samples.
    Type: Grant
    Filed: April 13, 2015
    Date of Patent: January 12, 2016
    Assignee: California Institute of Technology
    Inventors: Yu-Chong Tai, Siyang Zheng, Jeffrey Chun-Hui Lin, Harvey L. Kasdan
  • Publication number: 20150309011
    Abstract: Described herein are particular embodiments relating to a microfluidic device that may be utilized for cell sensing, counting, and/or sorting. Particular aspects relate to a microfabricated device that is capable of differentiating single cell types from dense cell populations. One particular embodiment relates a device and methods of using the same for sensing, counting, and/or sorting leukocytes from whole, undiluted blood samples.
    Type: Application
    Filed: April 13, 2015
    Publication date: October 29, 2015
    Applicant: California Institute of Technology
    Inventors: Yu-Chong Tai, Siyang Zheng, Jeffrey Chun-Hui Lin, Harvey L. Kasdan
  • Publication number: 20140273076
    Abstract: For analyzing a sample containing particles of at least two categories, such as a sample containing blood cells, a particle counter subject to a detection limit is coupled with an analyzer capable of discerning particle number ratios, such as a visual analyzer, and a processor. A first category of particles can be present beyond detection range limits while a second category of particles is present within respective detection range limits. The concentration of the second category of particles is determined by the particle counter. A ratio of counts of the first category to the second category is determined on the analyzer. The concentration of particles in the first category is calculated on the processor based on the ratio and the count or concentration of particles in the second category.
    Type: Application
    Filed: March 17, 2014
    Publication date: September 18, 2014
    Applicant: IRIS International, Inc.
    Inventors: Thomas H. Adams, Bart J. Wanders, John Roche, Harvey L. Kasdan
  • Publication number: 20100176918
    Abstract: A method and apparatus for detecting and tracking an object within a defined area, and determining its position, status, movement and identity therein, includes interrogating the defined area to communicate with an information device associated with an object and transmit information received to a master controller unit, which determines the object's presence, position, status, movement and identity within the defined area. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or the meaning of the claims.
    Type: Application
    Filed: February 18, 2010
    Publication date: July 15, 2010
    Inventors: Richard H. Turner, Harvey L. Kasdan
  • Patent number: 7692530
    Abstract: A method and apparatus for detecting and tracking an object within a defined area, and determining its position, status, movement and identity therein, includes interrogating the defined area to communicate with an information device associated with an object and transmit information received to a master controller unit, which determines the object's presence, position, status, movement and identity within the defined area. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or the meaning of the claims.
    Type: Grant
    Filed: March 1, 2006
    Date of Patent: April 6, 2010
    Inventors: Richard H. Turner, Harvey L. Kasdan
  • Patent number: 7671718
    Abstract: A method and apparatus for detecting and tracking an object with a defined area, and determining its position, status movement and identity therein, includes interrogating the defined area to communicate with an information device on object and transmit received to a master controller unit, which determines the object's presence, position, movement and identity with the defined area.
    Type: Grant
    Filed: January 21, 2005
    Date of Patent: March 2, 2010
    Inventors: Richard H. Turner, Harvey L. Kasdan
  • Patent number: 7324694
    Abstract: Most automatic particle classification methods produce errors. The invention provides a method for improving the accuracy of particle classification while shortening the amount of manual review time required from the operator. The method uses class weights, which are statistically-derived correction factors that accounts for frequency of classification errors. A first class weight and a second class weight are assigned to the first class and the second class, respectively. The number of particles in each of the first and the second classes is multiplied by the first class weight and the second class weight, respectively, to generate a corrected number of particles in each of the classes. If particles are reclassified, the class weights are recalculated in response to the reclassification. The method is usable with a complete classification where all the particles in a sample are classified, or a selective classification of a subset of the particles in the sample.
    Type: Grant
    Filed: May 21, 2004
    Date of Patent: January 29, 2008
    Assignee: International Remote Imaging Systems, Inc.
    Inventors: Eric Chapoulaud, Harvey L. Kasdan
  • Patent number: 7236623
    Abstract: A method and apparatus for classifying a plurality of elements in images, where electronic images of a field of view containing elements are formed. Each of the elements has a plurality of features. A first subgroup of the plurality of features from the images of the plurality of elements are extracted and processed to segregate the plurality of elements into first and second groups. A classification class only for each of the elements in the first group is determined by selecting and processing a second subgroup of the extracted features to determine a physical characteristic of the element, and by selecting and processing a third subgroup of the extracted features in response to the determined physical characteristic to determine a classification class of the element. The second group of elements bypasses the determination of classification class.
    Type: Grant
    Filed: November 18, 2003
    Date of Patent: June 26, 2007
    Assignee: International Remote Imaging Systems, Inc.
    Inventors: Eric Chapoulaud, Harvey L. Kasdan, Kenneth R. Castlemen, Kenneth N. Good
  • Patent number: 6947586
    Abstract: A multi-neural net imaging apparatus and method for classification of image elements, such as biological particles. The multi-net structure utilizes subgroups of particle features to partition the decision space by an attribute or physical characteristic of the particle and/or by individual and group particle classification that includes an unknown category. Preprocessing and post processing enables heuristic information to be included as part of the decision making process. Preprocessing classifies particles as artifacts based on certain physical characteristics. Post processing enables the use of contextual information either available from other sources or gleaned from the actual decision making process to further process the probability factors and enhance the decisions.
    Type: Grant
    Filed: April 24, 2001
    Date of Patent: September 20, 2005
    Assignee: International Remote Imaging Systems, Inc.
    Inventors: Harvey L. Kasdan, Michael R. Ashe, Minn Chung
  • Publication number: 20040126008
    Abstract: A method and apparatus for classifying a plurality of elements in images, where electronic images of a field of view containing elements are formed. Each of the elements has a plurality of features. A first subgroup of the plurality of features from the images of the plurality of elements are extracted and processed to segregate the plurality of elements into first and second groups. A classification class only for each of the elements in the first group is determined by selecting and processing a second subgroup of the extracted features to determine a physical characteristic of the element, and by selecting and processing a third subgroup of the extracted features in response to the determined physical characteristic to determine a classification class of the element. The second group of elements bypasses the determination of classification class.
    Type: Application
    Filed: November 18, 2003
    Publication date: July 1, 2004
    Inventors: Eric Chapoulaud, Harvey L. Kasdan, Kenneth R. Castleman, Kenneth N. Good