Abstract: A centrifuge device for separating different species of particles having different masses or sizes which are contained in a fluid medium, wherein the device comprises a plurality of adjacent channels positioned in a centrifugal field. The fluid medium flows through such channels and the channels are arranged such that portions of the fluid medium are successively diverted from one channel to the next in a cascaded manner. Accordingly, for separating particles of two different species, for example, portions of the fluid containing particles of one species and a fraction of the particles of the other species are so diverted in each case from one channel to the next adjacent one, while the remaining portions containing only particles of the other species continue to flow in the one channel.