Patents by Inventor Harvey R. Herschman

Harvey R. Herschman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclooxygenase-2 selective agents useful as imaging probes and related methods
    Patent number: 7329401
    Abstract: This invention provides novel cyclooxygenase-2 selective agents that are particularly useful as imaging probes in non-invasive imaging techniques, such as PET and SPECT. Preferred cyclooxygenase-2 selective agents inhibit cyclooxygenase-2 activity with greater potency and specificity than conventional cyclooxygenase-2 inhibitors. Other aspects of the invention include pharmaceutical compositions including the cyclooxygenase-2 selective agents as well as methods for detecting and/or inhibiting cyclooxygenase-2. These methods are particularly useful for diagnosing and treating disorders, such as inflammation, which is characterized by elevated cyclooxygenase-2 levels.
    Type: Grant
    Filed: January 10, 2003
    Date of Patent: February 12, 2008
    Assignee: The Regents of the University of California
    Inventors: Tatsushi Toyokuni, Nagichettiar Satyamurthy, Harvey R. Herschman, Michael E. Phelps, Jorge R. Barrio