Abstract: The present disclosure is related to a large-scale broadband wireless network capable of providing a very high wireless data capacity, wherein one aspect of the system utilizes a periodic beam forming system. When a wireless base station cell operates a periodic beam forming system, it is necessary to locate each user served by the cell within a sub-area covered by one of the m times N RF beams generated by the system. Methods for locating users within RF beam sub-areas are disclosed herein, where a user may be scheduled for transmission or reception only when an RF beam is focused on the sub-area that covers the user location. The present disclosure pertains to the systems and methods that may be used to process transmissions of and receptions by the baseband system of an LTE wireless base station that employs a periodic beam forming RF and antenna system.

Abstract: In embodiments of the present disclosure improved capabilities are described for increasing the bandwidth in a large area broadband network, where a scheduler facility, in association with a cellular LTE base transceiver station utilizing an agile beam forming antenna system, schedules communications between the LTE base transceiver station and mobile transceiver devices, wherein the scheduler facility schedules communications with a target mobile transceiver device to take place in one of the m times N RF beams of the agile beam forming antenna system based on a location determination of the target mobile transceiver device within the cell coverage area determined through a location determination algorithm that utilizes at least one of a channel quality indicator (CQI) measurement and a sounding reference signal (SRS) measurement collected through a communicative interaction between the cellular LTE base transceiver station and the target mobile transceiver device.

Abstract: Methods and systems having improved capabilities are described for providing communications to a plurality of cellular mobile devices through generating m different sets of fixed position patterns of N RF beams across the ten contiguous one-millisecond LTE sub-frames of each LTE time-division duplexing (TDD) frame from an agile beam forming antenna system of a cellular LTE base transceiver station. The cellular LTE base transceiver station is in RF TDD communication with the plurality of cellular mobile devices within a cell coverage area of the cellular LTE base transceiver station. Each RF beam covers a sub-area of the cell coverage area where the m times N RF beam patterns cover the area of the cell coverage area. The value of m is 1?m?3 and each one of the m sets of N RF beam patterns is generated in one or more of the non-S one-millisecond sub-frames of an LTE frame. The m sets of N RF beams are generated across any ten contiguous one-millisecond sub-frames.

Abstract: In embodiments of the present disclosure, improved capabilities are described for a sensor platform in a wireless network, where optimization servers utilizing publish-subscribe broker services are provided within the wireless network to provide conferenced connectivity between sensor devices and communicating entities.

Abstract: In embodiments of the present disclosure improved capabilities are described for reducing inter-cell interference in a large area broadband LTE wireless network utilizing RF agile beam forming antennas, where the reduced inter-cell interference is realized by arranging the sets of rotating RF beams in each cell such that adjacent RF beam sub-areas in the same or in different cells are not illuminated at the same time. The reduction in inter-cell interference results in reduced interference noise for users located near the edges of cells, thereby allowing them to be assigned higher data rates. Also, the same set of sub-carriers can be assigned by adjacent cells to users located in the RF beam sub-areas at the cell boundaries, thereby allowing the complete set of LTE sub-carriers to be assigned to any user at any time, without requiring additional cell-to-cell communications.

Abstract: In embodiments of the present disclosure, improved capabilities are described for conserving back haul utilization in a wireless network, where optimization servers utilizing publish-subscribe broker services are provided within the wireless network to provide streaming data services required for applications streaming data to a plurality of mobile cellular devices, where the streaming data is not necessarily delivered to each of the plurality of mobile cellular devices at the same time.

Abstract: The present invention provides a method for implementation in a wireless communication system including a plurality of base stations, a plurality of gateways, and a plurality of mobility management entities. The method includes receiving, at a first mobility management entity and from a first base station, measurement data collected by the first base station for a first mobile unit having a connection to the wireless communication system via the first base station. The measurement data includes a temporary identifier associated with the first mobile unit for the duration of the connection. The method also includes identifying the first mobile unit using the temporary identifier and forming a first record associated with the first mobile unit. The first record includes the measurement data collected by the first base station for the first mobile unit and previously collected measurement data for the first mobile unit.

Abstract: In embodiments of the present disclosure improved capabilities are described for increasing the bandwidth in a network, where centralized optimization servers are utilized to reduce the time-latency for applications being run from a user device. Further, by associating additional local optimization servers, application functionality may be optionally transferred from the centralized optimization server to the local optimization server in instances where a number of user devices are requesting the same data via their access through the same access node, and in other instances, to the effect that associated communication network bandwidth utilization is reduced or eliminated.

Abstract: In embodiments of the present disclosure, improved capabilities are described for a sensor platform in a wireless network, where optimization servers utilizing publish-subscribe broker services are provided within the wireless network to provide conferenced connectivity between sensor devices and communicating entities.

Abstract: In embodiments of the present disclosure improved capabilities are described for increasing the bandwidth in a wireless communication network, where centralized optimization servers with publish-subscribe broker services are utilized in conjunction with a queuing service application that provides packet service continuity when a mobile device moves between different access control nodes of the wireless communication network, and wherein the queuing service application is connected to a publish/subscribe broker network to receive service packets matching the service packets directed to the mobile device, wherein the service application makes the matching service packets available to the mobile device to replace service packets that the mobile device did not receive during a time in which the mobile device is in transition between being connected to any of the access control nodes.

Abstract: In embodiments of the present disclosure improved capabilities are described for increasing the bandwidth in a large area broadband LTE wireless network, where regional optimization servers are incorporated near the wireless network in association with the public data network gateway, thus reducing the time-latency for applications being run from a mobile cellular device. Further, by associating additional optimization servers at base stations, application functionality may be optionally transferred from the regional optimization server to the local base station optimization server in instances where a number of mobile cellular devices are requesting the same data via their access through the same cell, and in other instances, to the effect that back haul network bandwidth utilization is reduced or eliminated.

Abstract: A method for directed mining of a heterogeneous dataset with a computer comprising: populating a rule base with known rules, wherein each rule has a context and a situation; populating a case base with known cases, wherein each case has a context and a situation, and wherein the case base is partitioned from the rule base; ascribing a natural language semantics to predicates of the known cases and rules; randomly transforming the known rules and the known cases to form new rules by extracting a maximum number of common predicates; segmenting the rules and the cases on the basis of shared predicates without making distinction between context and situation predicates; abducing new knowledge from the dataset by fuzzily matching the context of a new rule to a situation the new rule does not cover; and issuing a query to a user to supply missing predicates of the fuzzy match.

Abstract: Methods and systems having improved capabilities are described for providing communications to a plurality of cellular mobile devices through generating m different sets of fixed position patterns of N RF beams across four contiguous one-millisecond LTE sub-frames from an agile beam forming antenna system of a cellular LTE base transceiver station. The cellular LTE base transceiver station is in RF frequency division duplexing (FDD) communication with the plurality of cellular mobile devices within a cell coverage area of the cellular LTE base transceiver station. Each RF beam illuminates a non-contiguous sub-area of the cell coverage area. A number m sets of RF beam patterns illuminate the area of the cell coverage area, wherein 1?m?4.

Abstract: In embodiments of the present disclosure improved capabilities are described for increasing the bandwidth in a wireless communication network, where centralized optimization servers with publish-subscribe broker services are utilized in conjunction with a queuing service application that provides packet service continuity when a mobile device moves between different access control nodes of the wireless communication network, and wherein the queuing service application is connected to a publish/subscribe broker network to receive service packets matching the service packets directed to the mobile device, wherein the service application makes the matching service packets available to the mobile device to replace service packets that the mobile device did not receive during a time in which the mobile device is in transition between being connected to any of the access control nodes.

Abstract: The present invention includes a luciferase-based high-throughput screening assay that identifies compounds that are inhibitors of cellular metabolism. This assay is applicable to all bacterial and eukaryotic membranes.

Abstract: In embodiments of the present disclosure improved capabilities are described for increasing the bandwidth in a network, where centralized optimization servers are utilized to reduce the time-latency for applications being run from a user device. Further, by associating additional local optimization servers, application functionality may be optionally transferred from the centralized optimization server to the local optimization server in instances where a number of user devices are requesting the same data via their access through the same access node, and in other instances, to the effect that associated communication network bandwidth utilization is reduced or eliminated.

Abstract: In embodiments of the present disclosure improved capabilities are described for a dual-use wireless network where the network may be used concurrently by the general public and by a managing agency (e.g., government or other agencies), but limited as deemed necessary in times of access restriction as determined by the managing agency, where network access may be denied to users/entities whose priority value is lower than the minimum allowed priority value set by the managing agency, or is not one of a set of allowed high priority access values or classes set by the managing agency.

Abstract: The present invention includes a method of treating or preventing a disease or disorder such as a mycobacterial infection, a Gram-positive bacterium infection, a yeast infection, an inflammatory condition, an auto-immune disorder and/or a proliferative disorder in a subject in need thereof. The method comprises administering to the subject a therapeutically effective amount of at least one compound of the invention, which includes clofazimine derivatives.

Abstract: The present invention relates to a method of using adaptive immunity to detect drug resistance in infectious diseases. The invention provides novel antigens associated with drug resistant MTB infection.

Abstract: In embodiments of the present disclosure improved capabilities are described for providing efficient delivery of real-time synchronous services over a large area broadband LTE wireless network, where optimization servers utilizing publish-subscribe broker services are provided within the wireless network to reduce the resources required for applications streaming data to a plurality of mobile cellular devices.