Patents by Inventor Hashim A. Ahmed

Hashim A. Ahmed has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dosage formulation
    Patent number: 8852634
    Abstract: The invention relates to a process for preparing a pharmaceutical tablet composition which comprises an active pharmaceutical ingredient of formula I wherein the definitions are described in claim 1, or pharmaceutically acceptable acid addition salts thereof and a water soluble poloxamer in which the compound of formula I and the water soluble poloxamer are processed by hot melt extrusion, and then the hot melt extrudate is mixed with other ingredients to form a tablet, that is optionally coated with a composition comprising an immediate release film coating system and purified water. The invention also relates to such pharmaceutical compositions and hot melt extrudates.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: October 7, 2014
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Hashim A. Ahmed, Susanne Page, Navnit Hargovindas Shah
  • NOVEL DOSAGE FORMULATION
    Publication number: 20110070303
    Abstract: The invention relates to a process for preparing a pharmaceutical tablet composition which comprises an active pharmaceutical ingredient of formula I wherein the definitions are described in claim 1, or pharmaceutically acceptable acid addition salts thereof and a water soluble poloxamer in which the compound of formula I and the water soluble poloxamer are processed by hot melt extrusion, and then the hot melt extrudate is mixed with other ingredients to form a tablet, that is optionally coated with a composition comprising an immediate release film coating system and purified water. The invention also relates to such pharmaceutical compositions and hot melt extrudates.
    Type: Application
    Filed: November 29, 2010
    Publication date: March 24, 2011
    Inventors: Hashim A. Ahmed, Susanne Page, Navnit Hargovindas Shah
  • Pharmaceutical composition and process
    Patent number: 7795237
    Abstract: The present invention relates to a pharmaceutical composition comprising a solid suspension prepared by hot melt extrusion of isobutyric acid (2R,3S,4R,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-2-azido-3,4-bis-iso-butyryloxy-tetrahydro-furan-2-ylmethyl ester; hydrochloride salt (I) and a polyethylene glycol (PEG)/polypropylene glycol (PPG) block copolymer.
    Type: Grant
    Filed: December 13, 2006
    Date of Patent: September 14, 2010
    Inventors: Hashim A. Ahmed, Thomas Vernon Alfredson, Kondamraj Birudaraj, Michael Thomas Brandl, Wantanee Phuapradit, Navnit Hargovindas Shah, Dimitrios Stefanidis