Patents by Inventor Hassan A. El-Sayad

Hassan A. El-Sayad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel compounds
    Patent number: 4761418
    Abstract: Neuromuscular blocking agents of formula (1) which are useful as skeletal muscle relaxants during surgery are disclosed. ##STR1## and X is an anion, preferably pharmaceutically acceptable.
    Type: Grant
    Filed: July 17, 1985
    Date of Patent: August 2, 1988
    Assignees: Burroughs Wellcome Co., General Hospital Corporation
    Inventors: Roy A. Swaringen, Jr., Hassan A. El-Sayad, David A. Yeowell, John J. Savarese
  • Long duration neuromuscular blocking agents
    Patent number: 4701460
    Abstract: Long duration muscle relaxant compound of formula (I) ##STR1## and its use in producing muscle relaxation in mammals including man.
    Type: Grant
    Filed: January 25, 1985
    Date of Patent: October 20, 1987
    Assignee: Burroughs Wellcome Co.
    Inventors: Hassan A. El-Sayad, Roy A. Swaringen, Jr., David A. Yeowell
  • Method of preparing isomers of bis isoquinolinium compounds
    Patent number: 4491665
    Abstract: This invention provides the neuromuscular blocking agents of formula (I): ##STR1## where B and C are each a group of formula (II) and are meta or para to one another: ##STR2## wherein D is CH.sub.2 CH.sub.2 or CH.dbd.CH (preferably trans); Y is alkyl of 1-4 carbon atoms (methyl, ethyl, propyl or butyl); E and F and H or OCH.sub.3 ; X.sup.- is an anion, preferably pharmaceutically acceptable; and the substituted benzyl and substituted propyl groups are in a trans relationship relative to each other in the nitrogen-containing ring.Methods for preparing the compounds, pharmaceutical formulations containing the compounds, and their use are also described.
    Type: Grant
    Filed: April 13, 1981
    Date of Patent: January 1, 1985
    Assignee: Burroughs Wellcome Co.
    Inventors: Hassan A. El-Sayad, Roy A. Swaringen, Jr., David A. Yeowell