Patents by Inventor Hassan Chaabihi

Hassan Chaabihi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant baculovirus and use thereof in the production of monoclonal antibodies
    Patent number: 6852507
    Abstract: Recombinant baculovirus used as an expression vector in the production of immunoglobulins with an insect cell. The invention is characterized by a first expression cassette comprising a first sequence coding for at least one portion of an immunoglobulin heavy chain, wherein the sequence is transcriptionally controlled by a first baculovirus promoter, and a second expression cassette comprising a second sequence coding for at least one portion of an immunoglobulin light chain, said second sequence being transcriptionally controlled by a second baculovirus promoter. The first and second promoters are two different promoters or derivatives of different promoters, the first and second promoters residing at different loci.
    Type: Grant
    Filed: November 21, 1997
    Date of Patent: February 8, 2005
    Assignees: Le Centre National de la Recherche Scientifique
    Inventors: Martine Cerutti, Hassan Chaabihi, Gerard Devauchelle, Laurent Gauthier, Michel Kaczorek, Marie-Paule LeFranc, Marie-Alix Poul
  • Monoclonal recombinant anti-rhesus D (D7C2) antibody
    Patent number: 6312690
    Abstract: Cloning of DNA fragments which code for the light chain or the heavy chain variable domain of the D7C2 monoclonal antibody within a baculovirus. The invention also concerns the expression of these DNA fragments in insect host cells, the anti-rhesus D recombinant monoclonal antibody so obtained and its use.
    Type: Grant
    Filed: July 1, 1997
    Date of Patent: November 6, 2001
    Assignees: Institut Pasteur, Proteine Performance
    Inventors: Léna Edelman, Christel Margaritte, Michel Kaczorek, Hassan Chaabihi