Patents by Inventor Hassan H. Fakih

Hassan H. Fakih has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TUMOR DELIVERY OF DENDRITIC OLIGONUCLEOTIDES
    Publication number: 20240401042
    Abstract: This disclosure provides compositions, systems, and methods for the delivery of therapeutic oligonucleotides to a tumor. The oligonucleotide is conjugated to a dendron comprising an end group, a phosphate group, and/or a hydrophobic chain.
    Type: Application
    Filed: March 19, 2024
    Publication date: December 5, 2024
    Inventors: Hassan H. Fakih, Hanadi Sleiman, Anastasia Khvorova, John E. Harris, Qi Tang, Ken Okamura
  • DENDRITIC CONJUGATES FOR THE LUNG DELIVERY OF THERAPEUTIC OLIGONUCLEOTIDES
    Publication number: 20240366773
    Abstract: This disclosure provides compositions, systems, and methods for the delivery of therapeutic oligonucleotides to the lung. The oligonucleotide is conjugated to a dendron comprising a hydrophilic end group, a phosphate group, and/or a hydrophobic chain.
    Type: Application
    Filed: March 1, 2024
    Publication date: November 7, 2024
    Inventors: Hassan H. Fakih, Hanadi Sleiman, Anastasia Khvorova, Jonathan K. Watts, Qi Tang, Minwook Shin
  • DENDRITIC CONJUGATES FOR THE BRAIN DELIVERY OF THERAPEUTIC OLIGONUCLEOTIDES
    Publication number: 20240360444
    Abstract: This disclosure provides compositions, systems, and methods for the delivery of therapeutic oligonucleotides to the brain. The oligonucleotide is conjugated to a dendron comprising a hydrophilic end group, a phosphate group, and/or a hydrophobic chain.
    Type: Application
    Filed: March 19, 2024
    Publication date: October 31, 2024
    Inventors: Hassan H. Fakih, Hanadi Sleiman, Anastasia Khvorova, Jonathan K. Watts, Samantha Sarli
  • DENDRITIC CONJUGATES FOR THE SKIN DELIVERY OF THERAPEUTIC OLIGONUCLEOTIDES
    Publication number: 20240350526
    Abstract: This disclosure provides compositions, systems, and methods for the delivery of therapeutic oligonucleotides to the skin. The oligonucleotide is conjugated to a dendron comprising a hydrophilic end group, a phosphate group, and/or a hydrophobic chain.
    Type: Application
    Filed: March 1, 2024
    Publication date: October 24, 2024
    Inventors: Hassan H. Fakih, Hanadi Sleiman, Anastasia Khvorova, Qi Tang, Katherine Gross, John E. Harris, Julia Alterman, Mohammad Zain Ul Abideen, Raymond Furgal
  • TOPICAL DELIVERY OF THERAPEUTIC OLIGONUCLEOTIDES
    Publication number: 20240325546
    Abstract: This disclosure provides compositions, systems, and methods for the topical delivery of therapeutic oligonucleotides with microneedle particles.
    Type: Application
    Filed: March 1, 2024
    Publication date: October 3, 2024
    Inventors: Hassan H. Fakih, Hanadi Sleiman, Anastasia Khvorova, Qi Tang, John E. Harris, Julia Alterman, Mohammad Zain Ul Abideen, Raymond Furgal
  • ULTRABRIGHT DNA NANOSTRUCTURES FOR BIOSENSING
    Publication number: 20230272470
    Abstract: Aspects of this disclosure relate to luminescently labeled nucleic acid nanostructures and methods and compositions for the detection and/or sequencing of one or more target molecules derived from a sample.
    Type: Application
    Filed: October 19, 2022
    Publication date: August 31, 2023
    Inventors: Xinghua Shi, Haidong Huang, Hassan H. Fakih, Hanadi F. Sleiman