Patents by Inventor Hassan Mziauf

Hassan Mziauf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ICA512 COUPLES INSULIN SECRETION AND GENE EXPRESSION IN BETA-CELLS
    Publication number: 20090131309
    Abstract: The present invention relates to a method for stimulating expression of peptide hormones in peptide-hormone secreting endocrine cells or neurons comprising the step of promoting in said cells or neurons the presence or activity (aa) of (i) ICA512; or (ii) a derivative thereof having ICA512 function; or (iii) a fragment of ICA512 that may be cleaved by ?-calpain giving rise to a C-terminal fragment of ICA512 wherein said C-terminal fragment has the capability of being targeted to the nucleus; or (iv) a derivative of said fragment of (iii) that may be cleaved by ?-calpain giving rise to a derivative of said C-terminal fragment of ICA512 wherein said derivative of said C-terminal fragment has the capability of being targeted to the nucleus; or (v) a fragment or derivative of ICA512 that may be cleaved by ?-calpain giving rise to a C-terminal fragment of ICA512 or derivative thereof wherein said C-terminal fragment or derivative thereof has the capability of interacting with a PIAS protein in said cells or neuron
    Type: Application
    Filed: September 2, 2005
    Publication date: May 21, 2009
    Applicant: Technische Universität Dresden Medizinizche Fakultät Carl Gustav Carus
    Inventors: Michele Solimena, Hassan Mziauf, Mirko Trajkovski