Patents by Inventor Hassan Qazzaz

Hassan Qazzaz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATING CANCER WITH CARDIAC GLYCOSIDES
    Publication number: 20110319351
    Abstract: The invention provides methods to treat cancer with cardiac glycosides.
    Type: Application
    Filed: May 10, 2011
    Publication date: December 29, 2011
    Applicant: University of Louisville Research Foundation
    Inventors: Roland Valdes, JR., Kenneth Ihenetu, Rafael Fernandes-Botran, Hassan Qazzaz
  • TREATING CANCER WITH CARDIAC GLYCOSIDES
    Publication number: 20090018088
    Abstract: The invention provides methods to treat cancer with cardiac glycosides.
    Type: Application
    Filed: June 2, 2008
    Publication date: January 15, 2009
    Applicant: University of Louisville Research Foundation
    Inventors: Roland Valdes, JR., Kenneth Ihenetu, Rafael Fernandes-Botran, Hassan Qazzaz
  • Dihydroouabain-like factor and diagnostic & therapeutic compositions and methods
    Publication number: 20050123999
    Abstract: A novel mammalian dihydroouabain-like factor is disclosed which substantially fails to cross-react with mammalian ouabain-like factor (OLF) for binding to anti-OLF antibody, but cross-reacts with plant-related dihydroouabain (dho) for binding to anti-dho antibody, has maximal u.v. absorbance at 196 nm, has a non-peptidic, non-lipidic chemical structure and a fully hydrogenated lactone ring, has a concentration-dependent Na+,K+-ATPase (sodium pump) catalytic inhibitory activity which is 10-fold lower than OLF and 3-fold higher than plant-related dihydroouabain, and a high pressure liquid chromatography elution time about the same as dho. This factor is useful for therapy for congestive heart failure. An antibody and antibody fragments having affinity for mammalian Dh-OLF but not for OLF, and diagnostic and therapeutic methods comprise the antibody and means for quantifying the antibody and are useful for treating a condition caused by high level of OLF or Dh-OLF.
    Type: Application
    Filed: November 15, 2004
    Publication date: June 9, 2005
    Inventors: Roland Valdes, Hassan Qazzaz