Patents by Inventor Hassan Serhan

Hassan Serhan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8425543
    Abstract: A method of removing a nucleus pulposus from an intervertebral disc, involving rotating a distal end head of an instrument so that flexible protrusions thereon will cut nucleus pulposus native material.
    Type: Grant
    Filed: December 14, 2005
    Date of Patent: April 23, 2013
    Assignee: DePuy Acromed
    Inventors: Hassan A. Serhan, Andrew Dooris
  • Publication number: 20130030471
    Abstract: A device intended for the treatment of spinal stenosis. This device is an inter-spinous spacer that is introduced through a single posterior incision. It uses a single piece insertion technique with a unilateral approach. The surgeon does not need to access the opposite side of the spinous process. It allows the user infinite adjustability in distraction height with a single locking mechanism.
    Type: Application
    Filed: July 27, 2012
    Publication date: January 31, 2013
    Inventors: Christopher Ramsay, Christine Rusbarsky, Katherine Selover, Glen Presbrey, Hassan Serhan
  • Patent number: 8361467
    Abstract: The present invention relates to trans-capsularly administering into a diseased joint a high specificity antagonist selected from the group consisting of: i) an inhibitor of a pro-inflammatory interleukin; ii) an inhibitor of TNF-? synthesis; iii) an inhibitor of membrane-bound TNF-?; iv) an inhibitor of a natural receptor of TNF-?; v) an inhibitor of NO synthase, vi) an inhibitor of PLA2 enzyme; vii) an anti-proliferative agent; viii) an anti-oxidant; ix) an apoptosis inhibitor selected from the group consisting of EPO mimetic peptides, EPO mimetibodies, IGF-I, IGF-II, and caspase inhibitors, and x) an inhibitor of MMPs; and xi) an inhibitor of p38 kinase.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: January 29, 2013
    Assignee: DePuy Spine, Inc.
    Inventors: Thomas M. DiMauro, Mohamed Attawia, Hassan Serhan, Martin A. Reynolds, Melissa Grace, Sudhakar Kadiyala, David Urbahns, Scott Bruder, Gregory Collins, Laura J. Brown, Jeff Geesin, Pamela L. Plouhar, Catherine Smith, John Siekierka
  • Patent number: 8333960
    Abstract: The present invention relates to administering autologous uncultured cells into a diseased intervertebral disc.
    Type: Grant
    Filed: October 31, 2008
    Date of Patent: December 18, 2012
    Assignee: DePuy Spine, Inc.
    Inventors: Mohamed Attawia, Hassan Serhan, Thomas M. DiMauro, Melissa Grace, David Urbahns
  • Patent number: 8323294
    Abstract: Various methods and devices are provided for tensioning a tether. In one embodiment, a tether tensioning device is provided and includes a tensioning mechanism adapted to couple to a tether extending along a path between at least two bone anchors implanted in adjacent vertebrae. The tensioning mechanism can be adapted to apply a tensioning force to the tether along the path of the tether to thereby move the tether along the path. The device further includes an actuation mechanism movably coupled to the tensioning mechanism such that the actuation mechanism is adapted to effect movement of the tensioning mechanism to control the tensioning force applied to the tether.
    Type: Grant
    Filed: August 21, 2007
    Date of Patent: December 4, 2012
    Assignee: DePuy Spine, Inc.
    Inventors: Christopher Mickiewicz, Michael A. Slivka, Matthew Hannen, Michael A. Fisher, Hassan A. Serhan, John Riley Hawkins
  • Patent number: 8313512
    Abstract: An S-shaped interspinous spacer having a pair of hooks that, upon lateral insertion between opposed spinous process, bear upon the opposed spinous processes.
    Type: Grant
    Filed: September 26, 2008
    Date of Patent: November 20, 2012
    Assignee: DePuy Spine, Inc.
    Inventors: Seungkyu Daniel Kwak, Mark Gracia, John Riley Hawkins, Lisa Gilman, John Griffin, Martin A. Reynolds, Hassan Serhan
  • Patent number: 8273086
    Abstract: Methods and devices for treating spinal deformities are provided. In one exemplary embodiment, a low-profile spinal anchoring device is provided for receiving a spinal fixation element, such as a tether, therethrough. The device generally includes a staple body that is adapted to seat a spinal fixation element, a fastening element for fixing the staple body to bone, and a locking assembly for coupling a spinal fixation element to the staple body. In one embodiment, the locking assembly includes a washer that is adapted to couple to the staple body such that the spinal fixation is disposed therebetween, and a locking nut that is adapted to engage the staple body to mate the washer to the staple body.
    Type: Grant
    Filed: March 24, 2005
    Date of Patent: September 25, 2012
    Assignee: DePuy Spine, Inc.
    Inventors: Hassan A. Serhan, Michael A. Slivka, Mathew Hannen, Peter Newton, Michael Nilsson
  • Patent number: 8273347
    Abstract: The present invention relates to administering autologous uncultured cells into a diseased intervertebral disc.
    Type: Grant
    Filed: November 14, 2003
    Date of Patent: September 25, 2012
    Assignee: DePuy Spine, Inc.
    Inventors: Mohamed Attawia, Hassan Serhan, Thomas M. DiMauro, Melissa Grace, David Urbahns
  • Patent number: 8267883
    Abstract: An implant comprises a photocatalytic layer on at least one surface and is adapted to act as a sensor. In some embodiments, the photocatalytic layer is a semiconductor oxide that is doped. According to some embodiments, the implant comprises a wave guide. According to some embodiments the implant comprises a light port. According to some embodiments, the implant comprises a reflective material on a surface of the waveguide. According to some embodiments the implant comprises a composite material comprising a first material that has a transmissivity when exposed to a predetermined wavelength of light and a second material that has photocatalytic activity when exposed to the predetermined wavelength of light. According to some embodiments the implant comprises a light source adapted to irradiate the photocatalytic surface.
    Type: Grant
    Filed: June 17, 2010
    Date of Patent: September 18, 2012
    Assignee: DePuy Spine, Inc.
    Inventors: Thomas M. DiMauro, Jeffrey K. Sutton, Mohamed Attawia, Hassan Serhan, John Daniel Malone, Timothy Beardsley
  • Patent number: 8267970
    Abstract: Various devices and methods are provided for spinal augmentation. In particular, the device can includes a connector element having a superior portion and an inferior portion that is adapted to support adjacent superior and inferior vertebrae and a first superior seating member and a second superior seating member associated with the connector element. The first seating member can be adapted to receive a portion of a lamina of the superior vertebra and the second seating member can be adapted to receive a portion of the lamina of the inferior vertebra. The device can have a variety of configurations, including the connector element and the first and second seating members being unitary and the first and second seating members being separately secured to the connector element.
    Type: Grant
    Filed: October 25, 2005
    Date of Patent: September 18, 2012
    Assignee: DePuy Spine, Inc.
    Inventors: Hassan A. Serhan, Michael A. Slivka
  • Patent number: 8133261
    Abstract: A implantable interference device configured for intra-facet placement within a facet joint is provided. The device includes a shank capable of engaging opposing faces of the facet joint. The shank can further include a head extending from a proximal end of the shank wherein the head is configured to engage and/or buttress opposing faces of the joint, and also configured for preventing over-insertion of the device. Optionally, at least a portion of the shank can include or be formed of a fusion-promoting bioactive material. Further, a method for providing fixation of a facet joint by intra-facet placement of an interference device within the facet joint is provided.
    Type: Grant
    Filed: August 22, 2007
    Date of Patent: March 13, 2012
    Assignee: DePuy Spine, Inc.
    Inventors: Michael Alan Fisher, Hassan A. Serhan, Michael J. O'Neil
  • Patent number: 8123749
    Abstract: Methods and devices for treating spinal deformities are provided. In one exemplary embodiment, a low-profile spinal anchoring device is provided for receiving a spinal fixation element, such as a tether, therethrough. The device generally includes a staple body that is adapted to seat a spinal fixation element, a fastening element for fixing the staple body to bone, and a locking assembly for coupling a spinal fixation element to the staple body. In one embodiment, the locking assembly includes a washer that is adapted to couple to the staple body such that the spinal fixation is disposed therebetween, and a locking nut that is adapted to engage the staple body to mate the washer to the staple body.
    Type: Grant
    Filed: March 24, 2005
    Date of Patent: February 28, 2012
    Assignee: DePuy Spine, Inc.
    Inventors: Hassan A. Serhan, Michael A. Slivka, Mathew Hannen, Peter Newton, Michael Nilsson
  • Patent number: 8097037
    Abstract: Method and devices are provided for correction of spinal deformities. The methods and devices are particularly useful for correcting an abnormal curvature of the spine. In one exemplary embodiment, the methods and devices provide a spinal implant that can include a wedged-shape configuration. The wedged implant can be interposed between adjacent vertebrae that form part of an abnormal spinal curvature, thereby realigning the vertebrae and restoring the normal curvature to the spine.
    Type: Grant
    Filed: December 20, 2006
    Date of Patent: January 17, 2012
    Assignee: DePuy Spine, Inc.
    Inventors: Hassan A. Serhan, Michael A. Slivka
  • Publication number: 20120010669
    Abstract: Spinal implants and methods for spinal stabilization and/or fusion are provided. Exemplary implants described herein can be configured for delivery to a facet joint to stabilize and/or fuse the facet joint, and can optionally be anchored within the pedicle for added fixation. The implant can optionally include a fusion-promoting bioactive material thereby providing a single device capable of spinal stabilization and/or fusion. Furthermore, a method of placing such an implant within a facet joint is provided.
    Type: Application
    Filed: July 12, 2010
    Publication date: January 12, 2012
    Applicant: DePuy Spine, Inc.
    Inventors: Michael O'Neil, John R. Hawkins, Michael A. Fisher, Robert M. Hart, Henri Defossez, Richard Fessler, Robert D. Labrom, Hassan A. Serhan, Duncan Betts, Shawn D. Stad
  • Publication number: 20120010662
    Abstract: Spinal implants and methods for spinal stabilization and/or fusion are provided. Exemplary implants described herein can be configured for delivery to a facet joint to stabilize and/or fuse the facet joint, and can optionally be anchored within the pedicle for added fixation. The implant can optionally include a fusion-promoting bioactive material thereby providing a single device capable of spinal stabilization and/or fusion. Furthermore, a method of placing such an implant within a facet joint is provided.
    Type: Application
    Filed: July 12, 2010
    Publication date: January 12, 2012
    Applicant: DePuy Spine, Inc.
    Inventors: Michael O'Neil, John R. Hawkins, Michael A. Fisher, Robert A. Hart, Richard Fessler, Robert D. LaBrom, Hassan A. Serhan, Shawn D. Stad
  • Publication number: 20110319999
    Abstract: An intervertebral fusion device comprising inferior and superior fusion cage devices that provide an ability to correct spondylolisthesis via in-situ adjustment.
    Type: Application
    Filed: June 17, 2011
    Publication date: December 29, 2011
    Inventors: Michael J. O'Neil, Hassan Serhan, Douglas Raymond, John Riley Hawkins
  • Publication number: 20110319940
    Abstract: Methods and devices that utilize segmental fixation between several adjacent vertebrae, thus allowing each vertebrae to be adjusted independently, are provided. In general, the device includes a spinal anchoring element that is adapted to seat at least one spinal fixation element, and a closure mechanism that is adapted to mate to the spinal anchoring element to lock the at least one spinal fixation element in a fixed position relative to the spinal anchoring element.
    Type: Application
    Filed: September 9, 2011
    Publication date: December 29, 2011
    Applicant: DEPUY SPINE, INC.
    Inventors: Michael A. Slivka, Hassan A. Serhan
  • Patent number: 8067397
    Abstract: The present invention relates to administering a doxycycline compound into a diseased intervertebral disc.
    Type: Grant
    Filed: May 14, 2009
    Date of Patent: November 29, 2011
    Assignee: DePuy Spine, Inc.
    Inventors: Mohamed Attawia, Thomas M. DiMauro, Hassan Serhan, Sudhakar Kadiyala, David Urbahns, Gregory Collins, Laura J. Brown, Jeffrey C. Geesin
  • Publication number: 20110288599
    Abstract: A bone anchor assembly includes a bone anchor, a receiver member for receiving a spinal fixation element to be coupled to the bone anchor, and a closure mechanism to fix the spinal fixation element with respect to the receiver member. The bone anchor includes a distal shaft having a distal threaded section and a proximal threaded section. The distal threaded section has a first pitch and a first number of thread starts and the proximal threaded section has a second pitch less than the first pitch and a second number of thread starts greater than the first number of thread starts. The distal threaded section and the proximal threaded section have a constant lead.
    Type: Application
    Filed: May 18, 2011
    Publication date: November 24, 2011
    Inventors: Michael Michielli, Bryan S. Jones, Philip Cormier, Hassan Serhan
  • Patent number: 8034085
    Abstract: Methods and devices that utilize segmental fixation between several adjacent vertebrae, thus allowing each vertebrae to be adjusted independently, are provided. In general, the device includes a spinal anchoring element that is adapted to seat at least one spinal fixation element, and a closure mechanism that is adapted to mate to the spinal anchoring element to lock the at least one spinal fixation element in a fixed position relative to the spinal anchoring element.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: October 11, 2011
    Assignee: DePuy Spine, Inc.
    Inventors: Michael A. Slivka, Hassan A. Serhan