Patents by Inventor Hatem Fessi
Hatem Fessi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11229597Abstract: The present invention relates to a novel pharmaceutical composition comprising doxycycline for topical application, in particular to the eye and eyelids. The invention also relates to this topical composition for use in the treatment of bacterial infections of the skin and mucous membranes.Type: GrantFiled: April 3, 2018Date of Patent: January 25, 2022Assignees: HORUS PHARMA, UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Marion Dubald, Sandrine Bourgeois, Hatem Fessi, Martine Claret
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Publication number: 20210100739Abstract: The present invention relates to a novel pharmaceutical composition comprising doxycycline for topical application, in particular to the eye and eyelids. The invention also relates to this topical composition for use in the treatment of bacterial infections of the skin and mucous membranes.Type: ApplicationFiled: April 3, 2018Publication date: April 8, 2021Inventors: Marion DUBALD, Sandrine BOURGEOIS, Hatem FESSI, Martine CLARET
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Patent number: 8999362Abstract: The present invention relates to novel nanoencapsulated compositions, methods for making such compositions, and methods of repelling insects and other arthropod pests away from animals, including humans. The present invention has particular, though not sole, application to repelling insects including flies and mosquitoes. The inventive compositions may be used to repel arthropods from animals, humans, plants, soil, or building structures. The formulations also prevent illness and disease caused by insect/pest-borne vectors, and provide safer, more effective alternatives to existing repellents.Type: GrantFiled: January 28, 2013Date of Patent: April 7, 2015Assignee: Merial, Inc.Inventors: Jean Delaveau, Audrey Minost, Hatem Fessi, Marie-Alexandrine Bolzinger, Abdelhamid Elaissari
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Publication number: 20140213643Abstract: The present invention relates to novel nanoencapsulated compositions, methods for making such compositions, and methods of repelling insects and other arthropod pests away from animals, including humans. The present invention has particular, though not sole, application to repelling insects including flies and mosquitoes. The inventive compositions may be used to repel arthropods from animals, humans, plants, soil, or building structures. The formulations also prevent illness and disease caused by insect/pest-borne vectors, and provide safer, more effective alternatives to existing repellents.Type: ApplicationFiled: January 28, 2013Publication date: July 31, 2014Applicant: MERIAL LIMITEDInventors: Jean Delaveau, Audrey Minost, Hatem FESSI, Marie-Alexandrine BOLZINGER, Abdelhamid Elaissari
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Patent number: 8414657Abstract: The invention concerns an injection implant for filling up wrinkles, thin lines, skin cracks and scars, for reparative or plastic surgery, aesthetic dermatology, and for filling up gums in dental treatment. The invention concerns the use of biologically absorbable polymer microspheres or microparticles suspended in a gel. The suspension is produced either ready-for-use or freeze-dried. The biological absorbability of the microspheres is controlled and enables the production of implants having well defined persistence and deliberately limited to 3 years.Type: GrantFiled: May 21, 2012Date of Patent: April 9, 2013Assignee: Valeant International BermudaInventors: Jerome Asius, Hatem Fessi, Franck Gouchet, Benedicte Laglenne, Elisabeth Laugher-Laglenne
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Publication number: 20120231046Abstract: The invention concerns an injection implant for filling up wrinkles, thin lines, skin cracks and scars, for reparative or plastic surgery, aesthetic dermatology, and for filling up gums in dental treatment. The invention concerns the use of biologically absorbable polymer microspheres or microparticles suspended in a gel. Said suspension is produced either ready-for-use or freeze-dried. The biological absorbability of the microspheres is controlled and enables the production of implants having well defined persistence and deliberately limited to 3 years.Type: ApplicationFiled: May 21, 2012Publication date: September 13, 2012Applicant: VALEANT INTERNATIONAL (BARBADOS) SRLInventors: Jérôme ASIUS, Hatem FESSI, Franck GOUCHET, Bénédicte LAGLENNE, Elisabeth LAUGHER-LAGLENNE
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Publication number: 20100221684Abstract: The invention concerns an injection implant for filling up wrinkles, thin lines, skin cracks and scars, for reparative or plastic surgery, aesthetic dermatology, and for filling up gums in dental treatment. The invention concerns the use of biologically absorbable polymer microspheres or microparticles suspended in a gel. Said suspension is produced either ready-for-use or freeze-dried. The biological absorbability of the microspheres is controlled and enables the production of implants having well defined persistence and deliberately limited to 3 years.Type: ApplicationFiled: May 10, 2010Publication date: September 2, 2010Applicant: Aventis PharmaceuticalsInventors: Jérôme Asius, Hatem Fessi, Franck Gouchet, Bénédicte Laglenne, Elisabeth Laugier-Laglenne
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Patent number: 7731758Abstract: The invention concerns an injection implant for filling up wrinkles, thin lines, skin cracks and scars, for reparative or plastic surgery, aesthetic dermatology, and for filling up gums in dental treatment. The invention concerns the use of biologically absorbable polymer microspheres or microparticles suspended in a gel. Said suspension is produced either ready-for-use or freeze-dried. The biological absorbability of the microspheres is controlled and enables the production of implants having well defined persistence and deliberately limited to 3 years.Type: GrantFiled: March 26, 2004Date of Patent: June 8, 2010Assignee: Aventis Pharmaceuticals Holdings, Inc.Inventors: Jérôme Asius, Hatem Fessi, Franck Gouchet, Bénedicte Laglenne, Elisabeth Laugier-Laglenne
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Patent number: 7348031Abstract: The invention relates to a process for the preparation of dispersible colloidal systems in the form of nanocapsules whose wall consists of a polymer obtained by the polycondensation of two monomers, ? and ?, and whose core consists of a substance B, characterized in that: (1) a first liquid phase is prepared which consists of a solution of monomer ? in a solvent or solvent mixture and contains one or more surfactants and the substance B in solution or suspension; (2) a second liquid phase is prepared which consists of a non-solvent or non-solvent mixture for the monomer ? and contains the monomer ? and one or more surfactants, the solvent or solvent mixture of the first phase being miscible in all proportions with the non-solvent or non-solvent mixture of the second phase; (3) the first phase is added to the second, with moderate agitation, to give a colloidal suspension of nanocapsules, agitation being maintained until the monomers ? and ? have completely polymerized; and (4) if desired, all or part of thType: GrantFiled: March 2, 2001Date of Patent: March 25, 2008Assignee: Universite Claude Bernard Lyon IInventors: Imed Montasser, Hatem Fessi, Stephanie Briancon, Joseph Lieto
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Patent number: 6884438Abstract: A process for the preparation of nanoparticles for the encapsulation of active constituents, the nanocapsules prepared being dispersible in aqueous phase in colloidal form, non-toxic, biocompatible, stable in colloidal suspension and economical. In the process, two non-oily solvents as used, together with a third, oily solvent.Type: GrantFiled: July 21, 1998Date of Patent: April 26, 2005Assignee: Universite Claude Bernard Lyon IInventors: David Quintanar, Hatem Fessi, Eric Doelker, Eric Allemann
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Publication number: 20040191323Abstract: The invention concerns an injection implant for filling up wrinkles, thin lines, skin cracks and scars, for reparative or plastic surgery, aesthetic dermatology, and for filling up gums in dental treatment. The invention concerns the use of biologically absorbable polymer microspheres or microparticles suspended in a gel. Said suspension is produced either ready-for-use or freeze-dried. The biological absorbability of the microspheres is controlled and enables the production of implants having well defined persistence and deliberately limited to 3 years.Type: ApplicationFiled: March 26, 2004Publication date: September 30, 2004Applicant: Aventis Pharmaceuticals holdings, Inc.Inventors: Jerome Asius, Hatem Fessi, Franck Gouchet, Benedicte Laglenne, Elisabeth Laugier-Laglenne
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Patent number: 6716251Abstract: The invention concerns an injection implant for filling up wrinkles, thin lines, skin cracks and scars, for reparative or plastic surgery, aesthetic dermatology, and for filling up gums in dental treatment. The invention concerns the use of biologically absorbable polymer microspheres or microparticles suspended in a gel. Said suspension is produced either ready-for-use or freeze-dried. The biological absorbability of the microspheres is controlled and enables the production of implants having well defined persistence and deliberately limited to 3 years.Type: GrantFiled: February 8, 1999Date of Patent: April 6, 2004Assignee: Aventis Pharmaceuticals Holdings, Inc.Inventors: Jérôme Asius, Hatem Fessi, Franck Gouchet, Bénédicte Laglenne, Elisabeth Laugier-Laglenne
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Publication number: 20030059473Abstract: The invention relates to a process for the preparation of dispersible colloidal systems in the form of nanocapsules whose wall consists of a polymer obtained by the polycondensation of two monomers, &agr; and &bgr;, and whose core consists of a substance B, characterized in that:Type: ApplicationFiled: October 18, 2002Publication date: March 27, 2003Inventors: Imed Montasser, Hatem Fessi, Stephanie Briancon, Joseph Lieto
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Patent number: 6229009Abstract: A cross-linked copolymer based on at least one non-crosslinked polycarboxylic polysaccharide and at least one second non-crosslinked polycarboxylic polymer which is not a polycarboxylic polysaccharide and a cross-linking agent having at least two amine functions.Type: GrantFiled: February 18, 1999Date of Patent: May 8, 2001Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)Inventors: Nada Lambert, Denis Labarre, Hatem Fessi
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Patent number: 5718905Abstract: A nanoparticulate system prepared by: 1) preparing a liquid phase essentially consisting of a solution of cyclodextrin modified by acyl groups in an organic solvent or solvent mixture, an active molecule being optionally added thereto; 2) preparing a second liquid phase essentially consisting of water or an aqueous mixture optionally containing one or more surfactants, and optionally having an active molecule added thereto; and 3) gently stirring one of the liquid phases resulting from 1) or 2) into the other in order to obtain, almost instantaneously, a colloidal solution of modified cyclodextrin nanospheres. If required, all or part of the solvent and all or part of the water may be removed. The system may be used as a carrier for pharmaceuticals, cosmetics, chemicals, etc.Type: GrantFiled: March 8, 1995Date of Patent: February 17, 1998Assignee: Centre National de la Recherche Scientifique (C.N.R.S.)Inventors: Mohamed Skiba, Denis Wouessidjewe, Antony Coleman, Hatem Fessi, Jean-Philippe Devissaguet, Dominique Duchene, Francis Puisieux
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Patent number: 5174930Abstract: Dispersible colloidal systems of amphiphilic lipids in the form of oligolamellar liposomes of submicron dimensions are prepared by combining a first liquid phase consisting essentially of a solution of the lipids with a greater amount of a second liquid phase consisting essentially of water. The solvent for the first liquid phase is miscible in all proportions with water. If desired, the first liquid phase may also contain a substance A in solution therewith, such as cholesterol. An additional substance B, which is a biologically active substance, may be present in the first phase if it is lipophilic, and in the second phase if it is hydrophilic.Type: GrantFiled: March 6, 1991Date of Patent: December 29, 1992Assignee: Centre National de la Recherche Scientifique (CNRS)Inventors: Serge Stainmesse, Hatem Fessi, Jean-Philippe Devissaguet, Francis Puisieux
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Patent number: 5133908Abstract: The Process according to the invention comprises:(1) the preparation of a liquid phase consisting essentially of a solution of the substance in a solvent or in a mixture of solvents to which may be added one or more surfactants,(2) the preparation of a second liquid phase consisting essentially of a non-solvent of a mixture of non-solvents for the substance and to which may be added one or more surfactants, the non-solvent or the mixture of non-solvents for the substance being miscible in all proportions with the solvent or the mixture of solvents for the substance,(3) the addition of one of the liquid phases prepared in (1) or (2) to the other with moderate stirring so as to produce a colloidal suspension of nanoparticles of the substance and,(4) if desired, the removal of all or part of the solvent or the mixture of solvents for the substance and of the non-solvent or the mixture of non-solvents for the substance so as to produce a colloidal suspension of nanoparticles of the desired concentration or to proType: GrantFiled: June 30, 1989Date of Patent: July 28, 1992Assignee: Centre National de la Recherche Scientifique (CNRS)Inventors: Serge Stainmesse, Hatem Fessi, Jean-Phillppe Devissaguet, Francis Puisieux, Curt Theis
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Patent number: 5049322Abstract: The process according to the invention comprises:(1) the preparation of a liquid phase consisting essentially of a solution of a substance A in a solvent or in a mixture of solvents, and containing the substance B in solution or as a dispersion,(2) the preparation of a second liquid phase consisting essentially of a non-solvent or a mixture of non-solvents for the substances A and B, and supplemented with one or more surfactants, the solvent or mixture of solvents of the first phase being miscible in all proportions with the non-solvent or mixture of non-solvents of the second phase,(3) the addition of the first phase to the second phase with moderate agitation so as to produce a colloidal suspension of nanocapsules, the wall of which is constituted by the substance A and the core by the substance B,(4) if desired, the removal of all or part of the solvent or the mixture of solvents and of the non-solvent or the mixture of non-solvents so as to produce a colloidal suspension of nanocapsules of the desired conType: GrantFiled: December 31, 1987Date of Patent: September 17, 1991Assignee: Centre National de la Recherche Scientifique (C.N.R.S.)Inventors: Jean-Philippe Devissaguet, Hatem Fessi, Francis Puisieux