Patents by Inventor Hatice Akarsu

Hatice Akarsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Influenza A virus with attenuating mutations in NS2 protein
    Patent number: 8507247
    Abstract: The invention provides an isolated attenuated recombinant influenza virus comprising a gene segment comprising a mutant NS2 protein gene, wherein the NS2 protein has at least two substitutions that do not substantially alter the in vitro replication of the virus but are associated with attenuation of the virus in vivo, wherein at least one of the substitutions is a substitution for glutamate.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: August 13, 2013
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Yoshihiro Kawaoka, Hatice Akarsu, Kiyoko Iwatsuki-Horimoto
  • ATTENUATING MUTATIONS IN THE INFLUENZA A VIRUS NEP(=NS2) PROTEIN
    Publication number: 20110081373
    Abstract: The invention provides an isolated attenuated recombinant influenza virus comprising a gene segment comprising a mutant NS2 protein gene, wherein the NS2 protein has at least two substitutions that do not substantially alter the in vitro replication of the virus but are associated with attenuation of the virus in vivo, wherein at least one of the substitutions is a substitution for glutamate.
    Type: Application
    Filed: August 11, 2010
    Publication date: April 7, 2011
    Applicant: WARF - Wisconsin Alumni Research Foundation
    Inventors: Yoshihiro Kawaoka, Hatice Akarsu, Kiyoko Iwatsuki-Horimoto