Patents by Inventor Haukur Johanneson

Haukur Johanneson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of magnetic resonance investigation of a sample using a nuclear spin polarised MR imaging agent
    Patent number: 7346384
    Abstract: The present invention provides a method of contrast enhanced magnetic resonance imaging of a sample, said method comprising: a) administering a hyperpolarised MR contrast agent comprising non-zero nuclear spin nuclei into said sample for fluid dynamic investigations of the vasculature, b) exposing said sample or part of the sample to radiation of a frequency selected to excite nuclear spin transitions in said non-zero nuclear spin nuclei, c) detecting MR signals from said sample using any suitable manipulation method including pulse sequences. The invention also provides novel compounds.
    Type: Grant
    Filed: March 11, 2003
    Date of Patent: March 18, 2008
    Assignee: GE Healthcare AS
    Inventors: Stefan Petersson, Oskar Axelsson, Haukur Johanneson
  • Para-hydrogen labeled agents and their use in magnetic resonance imaging
    Publication number: 20040024307
    Abstract: The invention provides a method of magnetic resonance investigation of a sample, said method comprising: (i) reacting para-hydrogen enriched hydrogen with a hydrogenatable MR imaging agent precursor containing a non-hydrogen non-zero nuclear spin nucleus to produce a hydrogenated MR imaging agent; (ii) administering said hydrogenated MR imaging agent to said sample; (iii) exposing said sample to radiation of a frequency selected to excite nuclear spin transitions of said non-zero nuclear spin nucleus in said hydrogenated MR imaging agent; (v) detecting magnetic resonance signals of said non-zero nuclear spin nucleus from said sample; and (vi) optionally, generating an image or biological functional data or dynamic flow data from said detected signals.
    Type: Application
    Filed: March 24, 2003
    Publication date: February 5, 2004
    Applicant: Amersham Health AS
    Inventors: Klaes Golman, Oskar Axelsson, Haukur Johanneson, Charlotte Olofsson, Sven Mansson, Stefan Petersson
  • Method of magnetic resonance investigation of a sample using a nuclear spin polarised MR imaging agent
    Publication number: 20030212323
    Abstract: The present invention provides a method of contrast enhanced magnetic resonance imaging of a sample, said method comprising: a) administering a hyperpolarised MR contrast agent comprising non-zero nuclear spin nuclei into said sample for fluid dynamic investigations of the vasculature, b) exposing said sample or part of the sample to radiation of a frequency selected to excite nuclear spin transitions in said non-zero nuclear spin nuclei, c) detecting MR signals from said sample using any suitable manipulation method including pulse sequences. The invention also provides novel compounds.
    Type: Application
    Filed: March 11, 2003
    Publication date: November 13, 2003
    Inventors: Stefan Petersson, Oskar Axelsson, Haukur Johanneson
  • Para-hydrogen labelled agents and their use in magnetic resonance imaging
    Patent number: 6574495
    Abstract: The invention provides a method of magnetic resonance investigation of a sample, said method comprising: (i) reacting para-hydrogen enriched hydrogen with a hydrogenatable MR imaging agent precursor containing a non-hydrogen non-zero nuclear spin nucleus to produce a hydrogenated MR imaging agent; (ii) administering said hydrogenated MR imaging agent to said sample; (iii) exposing said sample to radiation of a frequency selected to excite nuclear spin transitions of said non-zero nuclear spin nucleus in said hydrogenated MR imaging agent; (v) detecting magnetic resonance signals of said non-zero nuclear spin nucleus from said sample; and (vi) optionally, generating an image or biological functional data or dynamic flow data from said detected signals.
    Type: Grant
    Filed: May 5, 2000
    Date of Patent: June 3, 2003
    Assignee: Amersham Health AS
    Inventors: Klaes Golman, Oskar Axelsson, Haukur Johanneson, Charlotte Olofsson, Sven Mansson, Stefan Petersson