Patents by Inventor Hava Avraham

Hava Avraham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of detection and treatment of breast cancer
    Publication number: 20030181404
    Abstract: Novel methods of detecting and treating breast cancer are described.
    Type: Application
    Filed: March 14, 2002
    Publication date: September 25, 2003
    Applicant: Beth Israel Deaconess Medical Center
    Inventors: Hava Avraham, Jerome E. Groopman
  • Methods of detection and treatment of breast cancer
    Patent number: 6368796
    Abstract: Novel methods of detecting and treating breast cancer are described.
    Type: Grant
    Filed: May 20, 1999
    Date of Patent: April 9, 2002
    Assignee: Beth Israel Deaconess Medical Center
    Inventors: Hava Avraham, Jerome E. Groopman
  • Neural cell protein marker RR/B and DNA encoding the same
    Patent number: 6066451
    Abstract: The invention contemplates the novel neural cell protein marker RR/B, cDNA encoding RR/B, nucleic acid probes for detection of mRNA encoding RR/B, synthetic polypeptides whose sequences correspond to a portion of RR/B and have a molecular weight equal to less than that of RR/B antibodies specific for RR/B, and methods for detection of RR/B.
    Type: Grant
    Filed: May 23, 1997
    Date of Patent: May 23, 2000
    Assignee: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Shalom Avraham, Hava Avraham, Jerome E. Groopman
  • Agonist murine monoclonal antibody as a stimulant for megakaryocytopoiesis
    Patent number: 5980893
    Abstract: A class of murine monoclonal antibodies that is capable of stimulating megakaryocytopoiesis in vitro has been raised against human megakaryocytic cells. The monoclonal antibody BAH-1 specifically recognizes and demonstrates agonist activity against the c-Mpl receptor on the megakaryocytic cell surface. In therapeutic applications, the BAH-1 and M4 monoclonal antibodies identified to date and similar antibodies (or active portions and chimeric combinations thereof) can stimulate proliferation of primary bone marrow megakaryocytes. Thus, the antibodies of the invention can be used to prepare a composition for treating, e.g., thrombocytopenia. A typical composition comprises a therapeutically effective amount of the BAH-1 monoclonal antibody in association with a pharmaceutically acceptable carrier vehicle.
    Type: Grant
    Filed: July 17, 1997
    Date of Patent: November 9, 1999
    Assignee: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Hava Avraham, Jerome E. Groopman
  • Methods of detection and treatment of breast cancer
    Patent number: 5981201
    Abstract: Novel methods of detecting and treating breast cancer are described.
    Type: Grant
    Filed: June 16, 1997
    Date of Patent: November 9, 1999
    Assignee: Beth Israel Deaconess Medical Center
    Inventors: Hava Avraham, Jerome E. Groopman
  • Neural cell protein marker RR/B and DNA encoding same
    Patent number: 5863744
    Abstract: The invention contemplates the novel neural cell protein marker RR/B, cDNA encoding RR/B, nucleic acid probes for detection of mRNA encoding RR/B, synthetic polypeptides whose sequences correspond to a portion of RR/B and have a molecular weight equal to less than that of RR/B, and methods for detection of RR/B.
    Type: Grant
    Filed: October 3, 1994
    Date of Patent: January 26, 1999
    Assignee: New England Deaconess Hospital Corporation
    Inventors: Shalom Avraham, Hava Avraham, Jerome E. Groopman
  • Differentiated megakaryocyte line producing novel megakaryocyte differentiation factor
    Patent number: 5686576
    Abstract: Differentiated megakaryocytes produced by introducing an activated oncogene into blast-megakaryocytes is disclosed. Also disclosed are novel megakaryocyte differentiation factors and platelets obtained from the differentiated megakaryocytes.
    Type: Grant
    Filed: June 6, 1994
    Date of Patent: November 11, 1997
    Assignee: New England Deaconess Hospital
    Inventors: Hava Avraham, Sally Cowley, Jerome Groopman