Patents by Inventor Havva Yagci Acar
Havva Yagci Acar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20210023239Abstract: The present invention relates to oligonucleotide carriers for oligonucleotide delivery to a subject to provide gene therapy. More particularly, the present invention relates to therapeutic nanoparticles for microRNA (miRNA) delivery to a subject. More particularly, the present invention relates to therapeutic nanoparticles wherein miRNA is bindable to biocompatible nanoparticles using natural gene carrier Argonaute (AGO) protein or a variant thereof. Optionally, therapeutic nanoparticles of the present invention additionally contain targeting moieties for targeting therapeutic nanoparticles to cancer cells and/or chemotherapeutic agents. Optionally, biocompatible nanoparticles are trackable nanoparticles, such as superparamagnetic iron oxide nanoparticles (SPION), to provide multifunctional theranostics.Type: ApplicationFiled: March 10, 2018Publication date: January 28, 2021Applicants: KOC UNIVERSITESI, SABANCI UNIVERSITESI, SABANCI UNIVERSITESI NANOTEKNOLOJI ARASTIRMA VE UYGULAMA MERKEZIInventors: Havva Yagci ACAR, Devrim GOZUACIK, Ali KOSAR, Ozlem UNAL, Muhammed KOCAK, Yunus AKKOC, Merve ZUVIN
-
Patent number: 10815424Abstract: Present invention provides a process for the synthesis of size and composition tunable colloidal PbMgS core and PbMgS/MS core shell quantum dots emitting in the near infrared (NIR) region of the spectrum in a single operation in a continuous flow reactor. M includes at least one of Cd, Mg, Zn and Cu metals.Type: GrantFiled: December 28, 2016Date of Patent: October 27, 2020Assignees: KUANTAG NANOTEKNOLOJILER GELISTIRME VE URETIM A.S., KOC UNIVERSITESIInventors: Leyla Dogan, Pinar Dagtepe, Ibrahim Hocaoglu, Osman Vedat Akgun, Havva Yagci Acar
-
Patent number: 10054565Abstract: The present invention relates to a real time identification method of working/functional fluid products including a specified tagging material and an apparatus which is first capturing and then identifying the tagging material using a concentrator and an optical detector, simultaneously transferring the reading to a smart unit and finally releasing the tagging material.Type: GrantFiled: October 17, 2017Date of Patent: August 21, 2018Assignees: Koc Universitesi, Kuantag Nanoteknolojiler Gelistirme ve Uretim A.S.Inventors: Hakan Urey, Havva Yagci Acar, Caglar Elbuken, Basarbatu Can, Osman Vedat Akgun, Fahri Kerem Uygurmen
-
Publication number: 20180038826Abstract: The present invention relates to a real time identification method of working/functional fluid products including a specified tagging material and an apparatus which is first capturing and then identifying the tagging material using a concentrator and an optical detector, simultaneously transferring the reading to a smart unit and finally releasing the tagging material.Type: ApplicationFiled: October 17, 2017Publication date: February 8, 2018Applicants: KOC UNIVERSITESI, KUANTAG NANOTEKNOLOJILER GELISTIRME VE URETIM A.S.Inventors: HAKAN UREY, HAVVA YAGCI ACAR, CAGLAR ELBUKEN, BASARBATU CAN, OSMAN VEDAT AKGUN, FAHRI KEREM UYGURMEN
-
Patent number: 9791407Abstract: The present invention relates to a real time identification method of working/functional fluid products including a specified tagging material and an apparatus which is first capturing and then identifying the tagging material using a concentrator and an optical detector, simultaneously transferring the reading to a smart unit and finally releasing the tagging material.Type: GrantFiled: October 23, 2012Date of Patent: October 17, 2017Assignees: Koc Universitesi, Kuantag Nanoteknolojiler Gelistirme ve Uretim A.S.Inventors: Hakan Urey, Havva Yagci Acar, Caglar Elbuken, Basarbatu Can, Osman Vedat Akgun, Fahri Kerem Uygurmen
-
Publication number: 20170190967Abstract: Present invention provides a process for the synthesis of size and composition tunable colloidal PbMgS core and PbMgS/MS core shell quantum dots emitting in the near infrared (NIR) region of the spectrum in a single operation in a continuous flow reactor. M includes at least one of Cd, Mg, Zn and Cu metals.Type: ApplicationFiled: December 28, 2016Publication date: July 6, 2017Applicants: KUANTAG NANOTEKNOLOJILER GELISTIRME VE URETIM A.S., KOC UNIVERSITESIInventors: LEYLA DOGAN, PINAR DAGTEPE, IBRAHIM HOCAOGLU, OSMAN VEDAT AKGUN, HAVVA YAGCI ACAR
-
Publication number: 20150300983Abstract: The present invention relates to a real time identification method of working/functional fluid products comprising a specified tagging material (2) and an apparatus which is first capturing and then identifying the tagging material by using concentrator (10) and optical detector (16), simultaneously transferring the reading to the smart unit (18) and finally releasing the tagging material.Type: ApplicationFiled: October 23, 2012Publication date: October 22, 2015Applicants: KOC UNIVERSITESI, KUANTAG NANOTEKNOLOJILER GELISTIRME VE URETIM A.S.Inventors: Hakan UREY, Havva YAGCI ACAR, Caglar ELBUKEN, Basarbatu CAN, Osman Vedat AKGUN, Fahri Kerem UYGURMEN
-
Patent number: 7714095Abstract: Polyether polymers, such as polyetherimides, are prepared by the reaction of a dihydroxy-substituted aromatic hydrocarbon alkali metal salt, such as bisphenol A disodium salt, with a bis(N-(chlorophthalimido))aromatic compound, such as 1,3- and/or 1,4-bis(N-(4-chlorophthalimido))benzene, in a solvent such as o-dichlorobenzene and in the presence of a phase transfer catalyst such as a hexaalkylguanidinium chloride. Several embodiments may be employed to improve the method. They comprise employing substantially dry reagents, employing a high solids level in solvent, beginning with an excess of bis(N-(chlorophthalimido))-aromatic compound and incrementally adding alkali metal salt, employing alkali metal salt of small particle size, and using reagents of high purity.Type: GrantFiled: February 28, 2006Date of Patent: May 11, 2010Assignee: Sabic Innovative Plastics IP B.V.Inventors: Daniel Joseph Brunelle, Havva Yagci Acar, Farid Fouad Khouri, Thomas Link Guggenheim, David Winfield Woodruff, Norman Enoch Johnson
-
Patent number: 7605222Abstract: Copolyetherimides compositions having high glass transition temperatures and outstanding ductility are presented. The copolyetherimides having Mw of at least 40,000 comprising isomeric bis(phthalimide) structural units within a relatively narrow range of isomer proportions exhibited Tgs of at least 240° C. and outstanding Notched Izod values. The copolyetherimides comprise oxydianiline residues and structural units of the formulas (I) and (II) (III).Type: GrantFiled: August 22, 2005Date of Patent: October 20, 2009Assignee: SABIC Innovative Plastics IP B.V.Inventors: Qing Ye, David Bruce Hall, William David Richards, Daniel Joseph Brunelle, Havva Yagci Acar
-
Patent number: 6849706Abstract: Copolyetherimides comprise phthalimide structural units comprising both 3- and 4-linkages, wherein the designations 3-linkage and 4-linkage refer to the isomeric positions on the phthalimide ring in the totality of phthalimide-comprising structural units in the copolymer. The products have excellent properties, including high glass transition and heat distortion temperatures, high ductility and good melt flow properties, and low polydispersity.Type: GrantFiled: August 25, 2003Date of Patent: February 1, 2005Assignee: General Electric CompanyInventors: Daniel Joseph Brunelle, Havva Yagci Acar, Farid Fouad Khouri, William David Richards
-
Patent number: 6797380Abstract: A nanoparticle comprising an inorganic core and a polymerizable outer coating. The inorganic core comprises a substantially crystalline inorganic material such as a superparamagnetic material. In one embodiment, the inorganic core comprises a single crystal mixed spinel ferrite comprising iron in a first oxidation state and at least one metal in a second oxidation state, wherein the second oxidation state is different from the first oxidation state.Type: GrantFiled: July 31, 2002Date of Patent: September 28, 2004Assignee: General Electric CompanyInventors: Peter John Bonitatebus, Jr., Havva Yagci Acar, Michael Larsen
-
Publication number: 20040023030Abstract: A nanoparticle comprising an inorganic core and a polymerizable outer coating. The inorganic core comprises a substantially crystalline inorganic material such as a superparamagnetic material. In one embodiment, the inorganic core comprises a single crystal mixed spinel ferrite comprising iron in a first oxidation state and at least one metal in a second oxidation state, wherein the second oxidation state is different from the first oxidation state.Type: ApplicationFiled: July 31, 2002Publication date: February 5, 2004Applicant: General Electric CompanyInventors: Peter John Bonitatebus, Havva Yagci Acar, Michael Larsen
-
Publication number: 20040022937Abstract: A method of forming a plurality of monodisperse nanoparticles. Each of the nanoparticles comprises a nanocrystalline inorganic core and at least one outer coating comprising an ionizable stabilizing material that substantially covers the core. The method comprises the steps of: combining a nonpolar aprotic organic solvent, an oxidant, and a first surfactant; providing at least one organometallic compound to the combined nonpolar aprotic organic solvent, oxidant, and first surfactant; and heating the combined nonpolar aprotic organic solvent, oxidant, first surfactant, and the at least one organometallic compound under an inert gas atmosphere to a first temperature in a range from about 30° C. to about 400° C.Type: ApplicationFiled: July 31, 2002Publication date: February 5, 2004Applicant: General Electric CompanyInventors: Peter John Bonitatebus, Havva Yagci Acar