Patents by Inventor Hayao Abe

Hayao Abe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and pharmaceutical compositions for treating immunodeficiencies
    Patent number: 5464816
    Abstract: A pharmaceutical composition containing serum thymic factor (FTS) and a method for using FTS containing compositions for treating a variety of immunodeficiencies and autoimmune diseases including multiple sclerosis, Guillain-Barre syndrome, inflammatory neuropathy, polyneuritis and other immunodemyelinating diseases.
    Type: Grant
    Filed: March 26, 1990
    Date of Patent: November 7, 1995
    Assignee: Mitsui Pharmaceuticals Inc.
    Inventors: Yoshitaka Nagai, Hayao Abe, Masanobu Arita
  • Method of treating disease caused by the infection of virus
    Patent number: 5352665
    Abstract: A medicament for prevention and remedy of diseases caused by the infection of viruses is disclosed, which is characterized by containing as an effective ingredient thereof a nonapeptide having the following amino acid configuration:pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn or an ester and an amide at the carboxyl group of the C-terminal of the asparagine or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: July 15, 1993
    Date of Patent: October 4, 1994
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Akira Awaya, Hisashi Kobayashi, Yusaku Ishizuka, Hayao Abe
  • Medicament for prevention and remedy of diseases of the pancreas and others
    Patent number: 5288706
    Abstract: A medicament for prevention and remedy of diseases of pancreas and others is disclosed, which is characterized by containing as an effective ingredient thereof a nonapeptide having the following amino acid configuration:pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asnor an ester and amide at the carboxyl group of the C-terminal of the asparagine or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: February 18, 1993
    Date of Patent: February 22, 1994
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Toshikazu Yamanouchi, Akira Awaya, Hisashi Kobayashi, Yusaku Ishizuka, Hayao Abe
  • Method for treating multiple sclerosis
    Patent number: 5112810
    Abstract: A pharmaceutical composition containing serum thymic factor (FTS) and a method for using FTS containing compositions for treating a variety of immunodeficiencies and autoimmune diseases including multiple sclerosis, Guillain-Barre syndrome, inflammatory neuropathy, polyneuritis and other immunodemyelinating diseases.
    Type: Grant
    Filed: May 15, 1985
    Date of Patent: May 12, 1992
    Assignee: Mitsui Pharmaceuticals, Inc.
    Inventors: Yoshitaka Nagai, Hayao Abe, Masanobu Arita
  • Sialic acid-bonded octapeptide and preparation thereof
    Patent number: 4963653
    Abstract: A sialic acid-bonded octapeptide represented by the following general formula (I): ##STR1## wherein R represents a hydrogen atom or an acetyl group; and R' represents a lower alkyl group, an aralkyl group, a hydrogen atom or an alkali metal atom, is herein disclosed. The peptide chain of the sialic acid-bonded octapeptide is constituted by 8 amino acid molecules on the C-terminus side of FTS and the compounds represented by formula (I) can be obtained by bonding sialic acid to the amino terminus of the peptide chain according to condensation. These octapeptides show excellent physiological activity comparable to FTS and a half life in blood longer than that of FTS and it is expected that the affinity of the peptide to lymphocytes is also enhanced. Thus they can effectively be used as medicines for treating the lowering and abnormality of functions of the thymus.
    Type: Grant
    Filed: June 28, 1989
    Date of Patent: October 16, 1990
    Assignees: Mect Corporation, Mitsui Toatsu Chemical, Inc.
    Inventors: Yoshitaka Nagai, Shohei Shibayama, Masaaki Numata, Shoji Yoshimura, Makoto Tanaka, Masayoshi Ito, Akira Awaya, Hisashi Kobayashi, Hayao Abe, Yusaku Ishizuka, Tomoya Ogawa