Patents by Inventor Hayato Nakagawa

Hayato Nakagawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VDR-silent vitamin D derivative as inhibitors of SREBP and pharmaceutical use thereof
    Patent number: 11932595
    Abstract: Provided are vitamin D3 derivatives of formula (I), pharmaceutical compositions thereof, and pharmaceutical or medical uses thereof for treating metabolic disease, a liver disease, obesity, diabetes, cardiovascular disease, or cancer in a patient in need thereof.
    Type: Grant
    Filed: September 17, 2021
    Date of Patent: March 19, 2024
    Assignee: KYOTO UNIVERSITY, NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY, TEIKYO UNIVERSITY and THE UNIVERSITY OF TOKYO
    Inventors: Motonari Uesugi, Yasushi Takemoto, Kazuo Nagasawa, Atsushi Kittaka, Fumihiro Kawagoe, Hayato Nakagawa
  • Tissue elasticity measurement device and measurement method
    Patent number: 11517287
    Abstract: There is provided a tissue elasticity measurement device 100 and a measurement method that allow for quantitative evaluation of biological changes related to tissue elasticity such as liver fibrosis. The tissue elasticity measurement device 100 has a supersonic wave measuring instrument 100a that measures a pulse waveform corresponding to a blood flow velocity by a pulse wave Doppler method, and an information processor 100b that calculates a deviation index value corresponding to a coefficient of variation from a pulse waveform obtained by the supersonic wave measuring instrument 100a.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: December 6, 2022
    Assignee: THE UNIVERSITY OF TOKYO
    Inventors: Yoko Soroida, Takuma Nakatsuka, Masaya Sato, Hayato Nakagawa, Hitoshi Ikeda, Kazuhiko Koike, Yutaka Yatomi
  • VDR-SILENT VITAMIN D DERIVATIVE AS INHIBITORS OF SREBP AND PHARMACEUTICAL USE THEREOF
    Publication number: 20220081381
    Abstract: Provided are vitamin D3 derivatives of formula (I), pharmaceutical compositions thereof, and pharmaceutical or medical uses thereof for treating metabolic disease, a liver disease, obesity, diabetes, cardiovascular disease, or cancer in a patient in need thereof.
    Type: Application
    Filed: September 17, 2021
    Publication date: March 17, 2022
    Inventors: Motonari Uesugi, Yasushi Takemoto, Kazuo Nagasawa, Atsushi Kittaka, Fumihiro Kawagoe, Hayato Nakagawa, Adil Salih Wakil
  • Tissue Elasticity Measurement Device and Measurement Method
    Publication number: 20200245974
    Abstract: There is provided a tissue elasticity measurement device 100 and a measurement method that allow for quantitative evaluation of biological changes related to tissue elasticity such as liver fibrosis. The tissue elasticity measurement device 100 has a supersonic wave measuring instrument 100a that measures a pulse waveform corresponding to a blood flow velocity by a pulse wave Doppler method, and an information processor 100b that calculates a deviation index value corresponding to a coefficient of variation from a pulse waveform obtained by the supersonic wave measuring instrument 100a.
    Type: Application
    Filed: March 7, 2018
    Publication date: August 6, 2020
    Inventors: Yoko SOROIDA, Takuma NAKATSUKA, Masaya SATO, Hayato Nakagawa, Hitoshi IKEDA, Kazuhiko KOIKE, Yutaka YATOMI
  • Animal model of nash-induced hepatocellular carcinoma and methods for developing specific therapeutics
    Patent number: 10034462
    Abstract: The invention provides a non-human animal model for non-alcoholic steatohepatitis (NASH)-induced heptocellular carcinoma, methods of screening for agents for treating heptocellular carcinoma, methods of screening for targets useful in suppressing NASH progression to heptocellular carcinoma, methods of treating heptocellular carcinoma, and compositions for treating the same.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: July 31, 2018
    Assignee: The Regents of the University of California
    Inventors: Michael Karin, Atsushi Umemura, Hayato Nakagawa
  • ANIMAL MODEL OF NASH-INDUCED HEPATOCELLULAR CARCINOMA AND METHODS FOR DEVELOPING SPECIFIC THERAPEUTICS
    Publication number: 20160360735
    Abstract: The invention provides a non-human animal model for non-alcoholic steatohepatitis (NASH)-induced heptocellular carcinoma, methods of screening for agents for treating heptocellular carcinoma, methods of screening for targets useful in suppressing NASH progression to heptocellular carcinoma, methods of treating heptocellular carcinoma, and compositions for treating the same.
    Type: Application
    Filed: June 10, 2016
    Publication date: December 15, 2016
    Inventors: Michael Karin, Atsushi Umemura, Hayato Nakagawa