Patents by Inventor Haydn Robert Sinclair

Haydn Robert Sinclair has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of cholera toxins by galatooligosaccharides (GOS)
    Patent number: 8202842
    Abstract: The invention relates to nutritional and pharmaceutical compositions comprising non-digestible galactooligosaccharides (GOS) and uses thereof. In particular, it relates to the use of GOS species in preventing or treating disease caused by bacterial toxins. Provided is the use of GOS having a polymerization degree of 5 or higher, preferably 6 or higher, for the manufacture of a nutritional or pharmaceutical composition for the treatment or prevention of an acute or chronic disease associated with or caused by the adhesion and/or uptake of a cholera toxin family member. Also provided is a method for providing a GOS fraction capable of inhibiting cholera toxin (Ctx) binding to GM1 and fractions obtainable thereby.
    Type: Grant
    Filed: October 1, 2007
    Date of Patent: June 19, 2012
    Assignee: Friesland Brands B.V.
    Inventors: Haydn Robert Sinclair, Jaap De Slegte, Gijsbertus Klarenbeek
  • INHIBITION OF CHOLERA TOXINS BY GALATOOLIGOSACCHARIDES (GOS)
    Publication number: 20100069322
    Abstract: The invention relates to nutritional and pharmaceutical compositions comprising non-digestible galactooligosaccharides (GOS) and uses thereof. In particular, it relates to the use of GOS species in preventing or treating disease caused by bacterial toxins. Provided is the use of GOS having a polymerization degree of 5 or higher, preferably 6 or higher, for the manufacture of a nutritional or pharmaceutical composition for the treatment or prevention of an acute or chronic disease associated with or caused by the adhesion and/or uptake of a cholera toxin family member. Also provided is a method for providing a GOS fraction capable of inhibiting cholera toxin (Ctx) binding to GM1 and fractions obtainable thereby.
    Type: Application
    Filed: October 1, 2007
    Publication date: March 18, 2010
    Applicant: FRIESLAND BRANDS B.V.
    Inventors: Haydn Robert Sinclair, Jaap de Slegte, Gijsbertus Klarenbeek