Patents by Inventor Hayley REECE

Hayley REECE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRYSTALLINE FORM OF LINACLOTIDE
    Publication number: 20150361139
    Abstract: Linaclotide is a guanylate cyclase type C receptor (GCC) agonist used in the treatment of gastrointestinal disorders and conditions, including irritable bowel syndrome and chronic constipation. Crystalline form II of Linaclotide is prepared in high purity and yields and shows superior chemical stability in comparison to known crystal or amorphous forms of Linaclotide. A process for the purification of Linaclotide is also provided.
    Type: Application
    Filed: January 28, 2014
    Publication date: December 17, 2015
    Inventors: Marijan STEFINOVIC, Myriam SCANSETTI, Hayley REECE
  • Crystalline Solids of a METAP-2 Inhibitor and Methods of Making and Using Same
    Publication number: 20150018413
    Abstract: The disclosure is in part directed to crystalline forms of 6-O-(4-dimethylaminoethoxy)cinnamoyl fumagillol and variants thereof.
    Type: Application
    Filed: February 12, 2014
    Publication date: January 15, 2015
    Applicant: Zafgen, Inc.
    Inventors: Thomas Crawford, Hayley A. Reece
  • Crystalline solids of a MetAP-2 inhibitor and methods of making and using same
    Patent number: 8735447
    Abstract: The disclosure is in part directed to crystalline forms of 6-O-(4-dimethylaminoethoxy)cinnamoyl fumagillol and variants thereof.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: May 27, 2014
    Assignee: Zafgen, Inc.
    Inventors: Thomas Crawford, Hayley A. Reece
  • Crystalline Solids of a METAP-2 Inhibitor and Methods of Making and Using Same
    Publication number: 20130197078
    Abstract: The disclosure is in part directed to crystalline forms of 6-O-(4-dimethylaminoethoxy)cinnamoyl fumagillol and variants thereof.
    Type: Application
    Filed: November 16, 2012
    Publication date: August 1, 2013
    Inventors: Thomas Crawford, Hayley A. Reece
  • Crystalline solids of a MetAP-2 inhibitor and methods of making and using same
    Patent number: 8349891
    Abstract: The disclosure is in part directed to crystalline forms of 6-O-(4-dimethylaminoethoxy)cinnamoyl fumagillol and variants thereof.
    Type: Grant
    Filed: August 7, 2012
    Date of Patent: January 8, 2013
    Assignee: Zafgen, Inc.
    Inventors: Thomas Crawford, Hayley A. Reece
  • Crystalline Solids of a METAP-2 Inhibitor and Methods of Making and Using Same
    Publication number: 20120316233
    Abstract: The disclosure is in part directed to crystalline forms of 6-O-(4- dimethylaminoethoxy)cinnamoyl fumagillol and variants thereof.
    Type: Application
    Filed: August 7, 2012
    Publication date: December 13, 2012
    Inventors: Thomas Crawford, Hayley A. Reece