Patents by Inventor Hayo de Jonge

Hayo de Jonge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4801608
    Abstract: A new solid bismuth containing composition which is colloidally soluble in water is obtained by spray drying an aqueous ammoniacal colloidal solution of bismuth citrate. The new composition is effective for the treatment of peptic ulcers.
    Type: Grant
    Filed: December 6, 1983
    Date of Patent: January 31, 1989
    Assignee: Gist-Brocades N. V.
    Inventors: Petrus J. H. Bos, Dirk J. C. Engel, Hayo de Jonge
  • Patent number: 4607029
    Abstract: Novel sodium amoxicillin preparations which are easily converted into stable, suitably injectable solutions which are free of allergic reactions-causing chemicals and which contain besides sodium amoxicillin, a small amount of sodium hydroxide and optionally also a small amount of sodium chloride, and a process for their preparation and a process for the preparation of aqueous sodium amoxicillin containing injection solutions. The sodium amoxicillin preparations are prepared by the as fast but gradual addition as possible of an excess of sodium hydroxide to a suspension of amoxicillin trihydrate in water until the amoxicillin has completely dissolved, whereafter optionally a part of the excess of base is immediately neutralized with hydrochloric acid while the temperature is kept between 0.degree.-30.degree. C., followed by sterile filtration of the obtained solution, freezing the solution and freeze drying the obtained solid in flasks or in bulk.
    Type: Grant
    Filed: April 23, 1985
    Date of Patent: August 19, 1986
    Assignee: Gist-Brocades N.V.
    Inventors: Hayo de Jonge, Jan W. Groenendaal, Gerrit J. Sijbrands, Annita Bagerman-Deetman